Results 51 to 60 of about 66,104,498 (114)

The effects of anti-sense interleukin-5 gene transferred by recombinant adeno-associated virus in allergic rats [PDF]

, 2008
The accumulation and infiltration of eosinophils in airways is one of the most important characteristics of asthma, and is mediated partly by secretion of IL-5 from Th2 lymphocytes.
Weining Xiong, Qingfeng Song, Yongjian Xu, Xiansheng Liu, Daxiong Zeng, Yong Cao, Chao Cao   +6 more
core  

Gastric and intestinal barrier impairment in tropical enteropathy and HIV: limited impact of micronutrient supplementation during a randomised controlled trial [PDF]

, 2010
Background Although micronutrient supplementation can reduce morbidity and mortality due to diarrhoea, nutritional influences on intestinal host defence are poorly understood.
Sanderson, IR, Sanderson Ian R, Shawa, T, Tamara Shawa, Shawa Tamara, Barclay G Robin, Stayner Mwanamakondo, G Robin Barclay, Ian R Sanderson, Soko Rose, Mwanamakondo Stayner, Kelly Paul, Mwanamakondo, S, Barclay, GR, Rose Soko, Paul Kelly, Geoff Smith, Smith Geoff, Soko, R, Smith, G, Kelly, P   +20 more
core   +2 more sources

BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemia [PDF]

, 2012
MECOM oncogene expression correlates with chronic myeloid leukaemia (CML) progression. Here we show that the knockdown of MECOM (E) and MECOM (ME) isoforms reduces cell division at low cell density, inhibits colony-forming cells by 34% and moderately ...
Jørgensen, Heather G., Holyoake, T.L., Holyoake, T., Abed El Baky, Mohamed, Bartholomew, C., Melo, Junia V., Roy, P., Melo, J.V., Abed El Baky, M., Roy, S., Jørgensen, H., Jorgensen, H.G., Strathdee, G., Strathdee, Gordon, Melo, J., Roy, Swagata, Holyoake, Tessa L., Roy, Poornima, Bartholomew, Christopher   +18 more
core   +1 more source

A dual origin for Bcr-Abl gene translocation/fusion as dynamics of synergism of the hematopoietic stem cell and hemangioblast in chronic myeloid leukemia [PDF]

, 2015
Contextual BCR-ABL tyrosine kinase over-activity determines in formulated fashion the emergence of proliferation and anti-apoptosis that arise largely as derived phenomena of otherwise homeostatic mechanisms of the c-ABL gene within hematopoietic ...
Agius, Lawrence M.
core   +1 more source

Eosinophilic enteritis requiring differentiation from chronic enteropathy associated with SLCO2A1 gene: A case report. [PDF]

World J Gastroenterol, 2023
Kimura K, Jimbo K, Arai N, Sato M, Suzuki M, Kudo T, Yano T, Shimizu T.   +7 more
europepmc   +1 more source

Genetic variability of the prion protein gene (PRNP) in wild ruminants from Italy and Scotland [PDF]

, 2009
The genetics of the prion protein gene (PRNP) play a crucial role in determining the relative susceptibility to transmissible spongiform encephalopathies (TSEs) in several mammalian species.
Acutis, Pier Luigi, Pier Luigi Acutis, Ezio Ferroglio, Simone Peletto, Hugh W. Reid, Perucchini, Matteo, Serena Robetto, Acin, Cristina, Bozzetta, Elena, Reid, Hugh W., Dalgleish, Mark P., Orusa, Riccardo, Elena Bozzetta, Ferroglio, Ezio, Sacchi, Paola, Paula Stewart, Daniela Meloni, Wilfred Goldmann, Meloni, Daniela, Gennero, Silvia, Riccardo Orusa, Roberto Rasero, Rasero, Roberto, Cristina Acín, Matteo Perucchini, Mark P. Dalgleish, Goldmann, Wilfred, Stewart, Paula, Maria Caramelli, Silvia Gennero, Caramelli, Maria, Robetto, Serena, Peletto, Simone, Paola Sacchi   +33 more
core   +1 more source

Novel IL10 gene family associations with systemic juvenile idiopathic arthritis [PDF]

, 2006
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases.
Woo, P, Samuel, JM, Gutierrez, Ana, Lewis, C M; id_orcid, Lewis, CM, Woo, Patricia, Samuel, J M, Fife, M S, Ogilvie, Emma M., Carmel JW Stock, Fife, MS, Lewis, Cathryn M., Emma M Ogilvie, Ogilvie, EM, Ana Gutierrez, Mack, LF, Fife, Mark S., Samuel, Jane M., Thomson, W, Cathryn M Lewis, Mark S Fife, Mack, L F, Mack, Lisa F., Ogilvie, E M, Gutierrez, A, Jane M Samuel, Stock, CJW, Stock, C J W, Stock, Carmel J W, Wendy Thomson, Thomson, Wendy, Patricia Woo, Lisa F Mack   +32 more
core   +1 more source

Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction [PDF]

, 2003
The diagnostic features and clinical course of three children (aged 1 month to 15 years) with severe functional intestinal obstruction and inflammation of the colonic lamina propria and myenteric plexus are described.
Smith, VV, Lindley, KJ, Milla, PJ, Schappi, MG   +3 more
core  

Protein-losing enteropathy associated with heart disease

, 2018
Protein-losing enteropathy is a rare complication of heart diseases associated with a chronic increase in systemic venous pressure. The most common cardiac cause of protein-losing enteropathy is found in patients after the Fontan operation.
Conall Morgan, Luc Mertens
core   +1 more source

Slco2a1 deficiency exacerbates experimental colitis via inflammasome activation in macrophages: a possible mechanism of chronic enteropathy associated with SLCO2A1 gene. [PDF]

Sci Rep, 2020
Nakata R, Nakamura Y, Hosomi S, Okuda H, Nishida Y, Sugita N, Itani S, Nadatani Y, Otani K, Tanaka F, Kamata N, Taira K, Nagami Y, Tanigawa T, Watanabe T, Yamagami H, Nakanishi T, Fujiwara Y.   +17 more
europepmc   +1 more source