, 2021 Background:: Environmental enteropathy (EE) contributes to growth failure in millions of children worldwide, but its relationship to clinical malnutrition has not been elucidated.
Amadi, B +10 more
core +3 more sources
Molecular Pathways Modulating the Severity of IgE-mediated Anaphylaxis [PDF]
, 2021 Food allergic reactions can involve cardiovascular, respiratory, cutaneous, gastrointestinal (GI) and neurologic organ systems. Clinical and experimental studies have provided corroborative evidence that upon food exposure, dietary antigens cross-link ...
Yamani, Amnah Nezar M
core +1 more source
The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions [PDF]
, 2016 INTRODUCTION: The in vivo fate and effectiveness of a drug depends highly on its absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).
Kovacsics, D., Laczka, Csilla, Patik, I.
core +1 more source
Anti-integrin αvβ6 antibody as a biomarker for diagnosing ulcerative colitis: a nationwide multicenter validation study. [PDF]
J GastroenterolBACKGROUND: A serum biomarker for diagnosing ulcerative colitis (UC) remains to be established. Although we recently reported an anti-integrin αvβ6 antibody (V6 Ab) for diagnosing UC with high sensitivity and specificity, no large-scale validation study ...
Okabe M +41 more
europepmc +3 more sources
Identifizierung neuer therapeutischer Zielstrukturen zur Beeinflussung metabolischer Umbauprozesse bei Herzinsuffizienz [PDF]
, 2022 Die Dissertation untersucht neue therapeutische Zielstrukturen zur Beeinflussung metabolischer Umbauprozesse bei Herzinsuffizienz. Dabei wird die Prolindehydrogenase und deren Effekte in Kardiomyozyten in Modellen für Herzinsuffizienz näher ...
Nitsche, Thilo Wilhelm
core
Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays [PDF]
The prostaglandin transporter (PGT, SLCO2A1) mediates transport of prostanoids (a.o. prostaglandin E2 (PGE2)) into cells and thereby promotes their degradation.
Adriaan P. IJzerman +8 more
core +1 more source
MULTISPECIES EVALUATION OF ANTIRETROVIRAL DISPOSITION IN A PUTATIVE TISSUE RESERVOIR OF HIV: IMPLICATIONS FOR ERADICATION [PDF]
, 2017 Ongoing HIV replication within gut lymphoid tissues may contribute to the persistence of HIV despite treatment with antiretrovirals (ARVs). ARVs may have reduced exposure in certain tissue areas, but current methods for assessing ARV tissue ...
Thompson, Corbin
core +2 more sources
Multiple Ileal and Colonic Stenoses: Is It Always Crohn’s Disease? [PDF]
A 62-year-old woman presented with multiple ileal and colonic stenoses, initially suspected to be Crohn's disease. Despite unremarkable endoscopic biopsies, surgery was performed due to clinical deterioration, and histological analysis confirmed the ...
Allocca, Mariangela +6 more
core +1 more source