Results 121 to 130 of about 2,076,544 (288)
Effective and Safe Pharmacotherapy for Chronic Gastritis
, 2023 The article presents the results of a genotypic study of patients with chronic gastritis in the Bukhara region for the rs1045642 polymorphism of the MDR-1 gene for the C3435T polymorphic marker.
G.S., Ochilova
core
Alimentary Pharmacology &Therapeutics, EarlyView.In this randomized, double‐blind trial in Mexican adults with erosive oesophagitis, tegoprazan did not significantly improve the primary 4‐week ITT healing endpoint versus pantoprazole (88.9% vs. 79.4%; p = 0.33), but produced faster symptom improvement. Encouraging per‐protocol and severe‐oesophagitis findings warrant confirmation.
José M. Remes‐Troche +9 more
wiley +1 more source
Journal of Physiological AnthropologyBackground Chronic gastritis caused by Helicobacter pylori (Hp) infection is a common gastrointestinal disorder. Despite the high prevalence of Hp infection and chronic gastritis in the Tibetan Plateau, there is a lack of studies elucidating the ...
Chunxia Li, Xuehong Wang, Sen Cui
doaj +1 more source
Research Progress of Banxia Xiexin Decoction in the Treatment of Chronic Gastritis
Banxia Xiexin decoction is a representative prescription of the acrid-opening and bitter-descending method, widely used for qi movement disorders and mixed coldheat patterns.
Yahui Huang, Jiayu Zhang
core +1 more source
Eosinophilic Oesophagitis and Incidence of Gastrointestinal Cancer: A Population‐Based Cohort Study
Alimentary Pharmacology &Therapeutics, EarlyView.Among 9115 patients with eosinophilic oesophagitis in Denmark, excess gastrointestinal cancer in the first year after diagnosis most likely reflected diagnostic work‐up. Beyond 1 year, oesophageal adenocarcinoma and hepatocellular carcinoma remained more frequent than expected; most patients with oesophageal cancer had prior Barrett's oesophagus ...
Gencer Kurt +4 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.A large data base of colonoscopies was analysed for mast cells. The data do not show a relationship between diarrhoea and elevated mast cells in the colonic mucosa. This study provides real‐world evidence against the routine diagnostic use of colonic mast cell quantification for the evaluation of diarrhoea.
Marlena Langreiter +2 more
wiley +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Cancer Science, EarlyView.In this prospective cohort study of 60,556 cancer‐free adults with a median follow‐up of 7.44 years, a higher Life's Essential 8 (LE8) score, reflecting better cardiovascular health, was associated with a lower risk of pancreatic cancer (PC). Each 1‐SD increase in LE8 score was associated with an 18% lower PC risk.
Liping Yi +8 more
wiley +1 more source
Cancer Science, EarlyView.Vagal cholinergic neurons promote gastric 5‐HT secretion, which drives gastric precancerous lesions through 5‐HTR1D and TRPV4, highlighting these as candidate targets for early intervention. ABSTRACT Gastric cancer (GC) is a leading lethal malignancy globally. Gastric precancerous lesion (GPL) represents a critical step in GC, but its neural regulatory
Shengli Gao +8 more
wiley +1 more source
Italian Patients Journey for Gene Therapy in Haemophilia A
Haemophilia, EarlyView.ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno +19 more
wiley +1 more source