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Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri +20 more
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A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco +2 more
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Chronic granulomatous disease [PDF]
Chronic granulomatous disease (CGD) is a rare congenital immunodeficiency characterized by recurrent bacterial and fungal infections as well as granuloma formation. The manifestations of this disease can involve single or multiple organ systems. The lungs are the most commonly affected organ; however, lymphatic, hepatic, skeletal, gastrointestinal ...
Alexander J, Towbin, Ian, Chaves
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Objective: To investigate granulomatous inflammation etiology based on clinical history and ancillary tests. Methods: Children aged
Ummühan Cay +4 more
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Chronic granulomatous disease [PDF]
Abstract Chronic granulomatous disease is a hereditable disorder in which polymorphs show diminished capacity for killing bacteria. Defective bactericidal activity results in protracted infection. The lesions of chronic granulomatous disease may affect all systems of the body.
J, Sutcliffe, A R, Chrispin
openaire +4 more sources
Clinical observation of Сhronic granulomatous disease in a 6-year-old child
Chronic granulomatous disease (CGD) is a hereditary disease caused by a genetic defect of violations of oxygen — dependent mechanisms of phagocytosis.
G. A. Kharchenko, O. G. Kimirilova
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Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis [PDF]
Acknowledgements: The authors would like to acknowledge Fraser P. Coxon and Ian Ganley for providing LC3-GFP-mCherry BMDMs. M.S.G. was supported by an FEMS research grant and F.L.v.d.V.
Alonso, M Fernanda +8 more
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Sarcoidosis-associated hepatocellular carcinoma [PDF]
Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma
Aiko, Satoshi +7 more
core +1 more source
Chronic granulomatous disease is an inborn error of immunity due to disrupted function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex.
Julia Scheiermann +22 more
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Chronic Granulomatous Disease: the Experience of Diagnosis and Treatment in Children
Chronic granulomatous disease — primary immunodeficiency with X-linked and autosomal recessive inheritance, characterized by impaired bactericidal function of phagocytic immune system.
L.I. Chernyshova +4 more
doaj +1 more source

