Results 241 to 250 of about 37,007 (288)
Oxidative Stress: Signaling Pathways, Biological Functions, and Disease
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu+4 more
wiley +1 more source
12 dogs with bilateral knee osteoarthritis were treated with either meloxicam or pentoxifylline over 60 days. Pentoxifylline showed superior reductions in inflammatory markers (CRP, IL‐1β, IL‐6, TNF‐α) and improved joint biochemical parameters, particularly hyaluronic acid levels and cartilage oligomeric matrix protein (COMP).
Kurtuluş Parlak+4 more
wiley +1 more source
Following glioblastoma resection with oxidized regenerated cellulose application, a patient developed an intracranial mass histopathologically linked to a microglial foreign body reaction in response to the hemostatic material. Mechanistic studies characterized the cytokine response and reduced viability of microglia, supporting the inflammatory ...
Joshua A. Kra+8 more
wiley +1 more source
Return of a racehorse to racing after iatrogenic lipoid pneumonia
Summary There is a paucity of literature describing equine lipoid pneumonia (LP) caused by inadvertent intrapulmonary administration of liquid paraffin (mineral oil). This case report improves our understanding of LP by describing; (1) the first reported return of a horse to racing after LP, (2) the likely benefits of prolonged dexamethasone ...
S. McCullagh+5 more
wiley +1 more source
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The Lancet, 1969
Abstract Significant abnormality of nitroblue tetrazolium (N.B.T.) oxidation, and of bacterial killing, in the fathers of patients with chronic granulomatous disease suggests a pattern of sex-modified autosomal recessive inheritance. The data suggest that the defect may be much commoner than is at present recognised.
JackC. Bass, StellaB. Kontras
+10 more sources
Abstract Significant abnormality of nitroblue tetrazolium (N.B.T.) oxidation, and of bacterial killing, in the fathers of patients with chronic granulomatous disease suggests a pattern of sex-modified autosomal recessive inheritance. The data suggest that the defect may be much commoner than is at present recognised.
JackC. Bass, StellaB. Kontras
+10 more sources
Pediatric and Developmental Pathology, 2003
CLINICAL SUMMARY A 3-year-old African-American boy presented with limping due to a thigh mass of recent appearance. The lesion was initially painless and nonmobile, without erythema or swelling. There was no fever or other constitutional symptom. Four days before admission, a second tumor appeared on the left parietal region.
Rebecca E. Rosenberg+4 more
openaire +6 more sources
CLINICAL SUMMARY A 3-year-old African-American boy presented with limping due to a thigh mass of recent appearance. The lesion was initially painless and nonmobile, without erythema or swelling. There was no fever or other constitutional symptom. Four days before admission, a second tumor appeared on the left parietal region.
Rebecca E. Rosenberg+4 more
openaire +6 more sources
Pediatric Radiology, 1981
The report describes a ten year old boy with a form of chronic granulomatous disease characterised by hepatic and tibial granulomatous, hilar and broncopulmonar inflammatory processes, and an absolute defect in PMN-mediated ADCC.
F. Bassani+3 more
openaire +3 more sources
The report describes a ten year old boy with a form of chronic granulomatous disease characterised by hepatic and tibial granulomatous, hilar and broncopulmonar inflammatory processes, and an absolute defect in PMN-mediated ADCC.
F. Bassani+3 more
openaire +3 more sources
Pediatric Clinics of North America, 1977
Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
openaire +3 more sources
Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
openaire +3 more sources
Annual Review of Medicine, 1992
Chronic granulomatous disease (CGD) encompasses a group of rare inherited disorders characterized by defects in a phagocyte-specific NADPH-oxidase complex that forms the superoxide radical during the respiratory burst. In this chapter, the protein components and cellular biochemistry of the oxidase are reviewed in light of recent genetic and ...
M C, Dinauer, S H, Orkin
openaire +4 more sources
Chronic granulomatous disease (CGD) encompasses a group of rare inherited disorders characterized by defects in a phagocyte-specific NADPH-oxidase complex that forms the superoxide radical during the respiratory burst. In this chapter, the protein components and cellular biochemistry of the oxidase are reviewed in light of recent genetic and ...
M C, Dinauer, S H, Orkin
openaire +4 more sources