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Chronic Granulomatous Disease in an Adult

Southern Medical Journal, 1987
We have described a 49-year-old man with chronic granulomatous disease. The diagnosis was established by a deficiency of NBT dye reduction by neutrophils, in addition to impairment in 14C-1-glucose utilization, 125I-iodination of zymosan, chemiluminescence, superoxide radical generation, and bactericidal activity toward S aureus.
L S, Nerurkar   +5 more
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The management of chronic granulomatous disease

European Journal of Pediatrics, 1993
Chronic granulomatous disease (CGD) is a primary immunodeficiency disease which results from absence of the NADPH oxidase in the professional phagocytic cells neutrophils, monocytes, macrophages and eosinophils. Deficiency of this oxidase renders the patient liable to infection by bacteria and fungi, and, as the name of the disease suggests, to chronic
A, Fischer   +3 more
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Chronic granulomatous disease in adults

The Lancet, 1996
Chronic granulomatous disease (CGD), an inherited disorder of granulocyte function caused by failure of intracellular superoxide production, normally presents in the first years of life with severe recurrent bacterial and fungal infections.From the files of two children's hospitals we identified 11 CGD patients who were remarkable for an unusually late
J G, Liese   +6 more
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AMANTADINE IN CHRONIC GRANULOMATOUS DISEASE

Pediatric Hematology and Oncology, 2005
Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis.
GRANZOTTO M   +7 more
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Prostatitis in chronic granulomatous disease

The American Journal of Medicine, 1989
On rapporte le premier cas d'abces de la prostate (Ps.
T L, Zach, P G, Quie
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Classification of Chronic Granulomatous Disease

Hematology/Oncology Clinics of North America, 1988
Chronic granulomatous disease is a heterogeneous disorder caused by at least three, and possibly four, types of mutations. Based on recent biochemical and molecular genetic data on this disease, a classification scheme and summary of the various forms of the disease are presented.
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Chronic Granulomatous Disease 1974

JAMA: The Journal of the American Medical Association, 1975
THE office diagnosis of many newly discovered diseases caused by neutrophil dysfunction is now possible with the use of clinical criteria and relatively simple laboratory tests. Through techniques evolved in the course of elucidating rare inborn disorders, it is now feasible to approach commonplace impairments of neutrophil function which occur as ...
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Chronic granulomatous disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
A J, Thrasher   +3 more
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Topics in Chronic Granulomatous Disease

Pediatrics, 1991
To the Editor.— Such phagocytic cells as neutrophils and macrophages are crucial elements in the host defense against bacterial [See table in the PDF file] and fungal infections. Microbicidal activity depends to a large extent on NADPH oxidase system, which can be activated by stimuli (bacteria, fungi) and ...
openaire   +2 more sources

Chronic Granulomatous Disease (CGD): Commonly Associated Pathogens, Diagnosis and Treatment

Microorganisms, 2023
Patrick Eberechi Akpaka   +2 more
exaly  

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