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Chronic Granulomatous Disease in an Adult
Southern Medical Journal, 1987We have described a 49-year-old man with chronic granulomatous disease. The diagnosis was established by a deficiency of NBT dye reduction by neutrophils, in addition to impairment in 14C-1-glucose utilization, 125I-iodination of zymosan, chemiluminescence, superoxide radical generation, and bactericidal activity toward S aureus.
L S, Nerurkar +5 more
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The management of chronic granulomatous disease
European Journal of Pediatrics, 1993Chronic granulomatous disease (CGD) is a primary immunodeficiency disease which results from absence of the NADPH oxidase in the professional phagocytic cells neutrophils, monocytes, macrophages and eosinophils. Deficiency of this oxidase renders the patient liable to infection by bacteria and fungi, and, as the name of the disease suggests, to chronic
A, Fischer +3 more
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Chronic granulomatous disease in adults
The Lancet, 1996Chronic granulomatous disease (CGD), an inherited disorder of granulocyte function caused by failure of intracellular superoxide production, normally presents in the first years of life with severe recurrent bacterial and fungal infections.From the files of two children's hospitals we identified 11 CGD patients who were remarkable for an unusually late
J G, Liese +6 more
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AMANTADINE IN CHRONIC GRANULOMATOUS DISEASE
Pediatric Hematology and Oncology, 2005Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis.
GRANZOTTO M +7 more
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Prostatitis in chronic granulomatous disease
The American Journal of Medicine, 1989On rapporte le premier cas d'abces de la prostate (Ps.
T L, Zach, P G, Quie
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Classification of Chronic Granulomatous Disease
Hematology/Oncology Clinics of North America, 1988Chronic granulomatous disease is a heterogeneous disorder caused by at least three, and possibly four, types of mutations. Based on recent biochemical and molecular genetic data on this disease, a classification scheme and summary of the various forms of the disease are presented.
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Chronic Granulomatous Disease 1974
JAMA: The Journal of the American Medical Association, 1975THE office diagnosis of many newly discovered diseases caused by neutrophil dysfunction is now possible with the use of clinical criteria and relatively simple laboratory tests. Through techniques evolved in the course of elucidating rare inborn disorders, it is now feasible to approach commonplace impairments of neutrophil function which occur as ...
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
A J, Thrasher +3 more
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A J, Thrasher +3 more
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Topics in Chronic Granulomatous Disease
Pediatrics, 1991To the Editor.— Such phagocytic cells as neutrophils and macrophages are crucial elements in the host defense against bacterial [See table in the PDF file] and fungal infections. Microbicidal activity depends to a large extent on NADPH oxidase system, which can be activated by stimuli (bacteria, fungi) and ...
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Chronic Granulomatous Disease (CGD): Commonly Associated Pathogens, Diagnosis and Treatment
Microorganisms, 2023Patrick Eberechi Akpaka +2 more
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