Results 71 to 80 of about 37,007 (288)

A Case of Chronic Granulomatous Disease with a Necrotic Mass in the Bronchus: A Case Report and a Review of Literature

Case Reports in Pulmonology, 2012
Chronic granulomatous disease is a rare phagocytic disorder with recurrent, severe bacterial and fungal infections. We describe an unusual case of chronic granulomatous disease manifesting as an invasive pulmonary aspergillosis with an obstructive ...
Ali Cheraghvandi, Majid Marjani, Saeid Fallah Tafti, Logman Cheraghvandi, Davoud Mansouri   +4 more
doaj   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +2 more sources

BCGiosis as a presenting feature of a child with chronic granulomatous disease

Brazilian Journal of Infectious Diseases, 2011
Bacillus Calmette Guerin (BCG) vaccine, which is administered to all newborns in some regions, could lead to serious complication ranging from local disease (known as BCGitis) to disseminated disease (BCGosis) in a group of patients with primary ...
Zahra Movahedi, Sayna Norouzi, Setareh Mamishi, Nima Rezaei   +3 more
doaj  

Successful Treatment of Pneumothorax in a Dog With Sterile Pleural Fibrosis Caused by Chylothorax [PDF]

, 2019
A 2-year-old, 12 kg, intact male crossbreed dog was presented with respiratory distress, exercise intolerance, and gagging. Plain thoracic radiographs revealed severe pleural effusion.
Gruber, Achim D., Kohn, Barbara, Manchi, George, Rehbein, Sina   +3 more
core   +1 more source

Gut microbiota and tuberculosis

iMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong   +39 more
wiley   +1 more source

Degranulation of leukocytes in chronic granulomatous disease [PDF]

, 1969
Robert L. Baehner, Morris J. Karnovsky, Manfred L. Karnovsky   +2 more
openalex   +2 more sources

Association of Eumycetoma and Schistosomiasis [PDF]

, 2013
Eumycetoma is a morbid chronic granulomatous subcutaneous fungal disease. Despite high environmental exposure to this fungus in certain regions of the world, only few develop eumycetoma for yet unknown reasons.
Belkum, A.F. (Alex) van, Fahal, A.H. (Ahmed), Hellemond, J.J. (Jaap) van, Koelewijn, R. (Rob), Sande, W.W.J. (Wendy) van de, Vaessen, N. (Norbert), Vogel, C.P. (Corné) de, Vonk, A.G. (Alieke)   +7 more
core   +4 more sources

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein, Jakob Ribbing, Moustafa M. A. Ibrahim, Wenhui Zhang, Nastya Kassir   +4 more
wiley   +1 more source

Recent advances in chronic granulomatous disease

Genes and Diseases, 2020
Chronic granulomatous disease (CGD) is an inherited defect of phagocyte function due to defective NADPH oxidase. Patients with CGD are not able to effectively clear the infections because of the defect in the phagocyte production of oxygen free radicals ...
Gummadi Anjani, Pandiarajan Vignesh, Vibhu Joshi, Jitendra Kumar Shandilya, Dharmagat Bhattarai, Jyoti Sharma, Amit Rawat   +6 more
doaj