Results 1 to 10 of about 543,750 (166)

Transcriptional landscape in rat intestines under hypobaric hypoxia [PDF]

PeerJ, 2021
Oxygen metabolism is closely related to the intestinal homeostasis environment, and the occurrence of many intestinal diseases is as a result of the destruction of oxygen gradients.
Liuyang Tian, Zhilong Jia, Zhenguo Xu, Jinlong Shi, XiaoJing Zhao, Kunlun He   +5 more
doaj   +2 more sources

Impacts of the Plateau Environment on the Gut Microbiota and Blood Clinical Indexes in Han and Tibetan Individuals

mSystems, 2020
The intestinal microbiota is significantly affected by the external environment, but our understanding of the effects of extreme environments such as plateaus is far from adequate. In this study, we systematically analyzed the variation in the intestinal
Zhilong Jia, Xiaojing Zhao, Xiaoshuang Liu, Le Zhao, Qian Jia, Jinlong Shi, Xiao Xu, Lijun Hao, Zhenguo Xu, Qin Zhong, Kang Yu, Saijia Cui, Huining Chen, Jianying Guo, Xiang Li, Yang Han, Xinyu Song, Chenghui Zhao, Xiaochen Bo, Yaping Tian, Weidong Wang, Guotong Xie, Qiang Feng, Kunlun He   +23 more
doaj   +3 more sources

The level of NT-proBNP in ambulatory patients with chronic heart failure with preserved ejection fraction of the left ventricle [PDF]

Терапевтический архив, 2018
The prevalence of chronic heart failure (CHF) remains high. Echocardiography is a reliable method of diagnosing heart failure. Determination of brain natriuretic peptide allows to identify patients with the most probable diagnosis of heart failure, which
V V Kirillova, L A Sokolova, V N Meshchaninov, V I Pershanova   +3 more
doaj   +1 more source

Correlation Between Plasma Proteomics and Adverse Outcomes Among Older Men With Chronic Coronary Syndrome

Frontiers in Cardiovascular Medicine, 2022
BackgroundChronic coronary syndrome (CCS) is a newly proposed concept and is hallmarked by more long-term major adverse cardiovascular events (MACEs), calling for accurate prognostic biomarkers for initial risk stratification.MethodsData-independent ...
Yu-Lun Cai, Yu-Lun Cai, Yu-Lun Cai, Ben-Chuan Hao, Ben-Chuan Hao, Ben-Chuan Hao, Jian-Qiao Chen, Jian-Qiao Chen, Jian-Qiao Chen, Yue-Rui Li, Yue-Rui Li, Hong-Bin Liu, Hong-Bin Liu   +12 more
doaj   +1 more source

Acute Lower Respiratory Tract Infection Increased the Risk of Cardiovascular Events and All-Cause Mortality in Elderly Patients With Stable Coronary Artery Disease

Frontiers in Cardiovascular Medicine, 2021
Objective: To investigate the predictors of acute cardiovascular events within 90 days after an acute lower respiratory tract infection (ALRTI) in elderly patients with stable coronary artery disease (sCAD).Methods: Observational analyses were conducted ...
Xiaoqian Zhao, Xiaoqian Zhao, Yuan Liu, Jinping Zhang, Shihui Fu, Chengyun Song, Yongyi Bai, Leiming Luo   +7 more
doaj   +1 more source

Cardiac Adaptation to Prolonged High Altitude Migration Assessed by Speckle Tracking Echocardiography

Frontiers in Cardiovascular Medicine, 2022
ObjectiveExposure to high altitudes represents physiological stress that leads to significant changes in cardiovascular properties. However, long-term cardiovascular adaptions to high altitude migration of lowlanders have not been described. Accordingly,
Xu Chen, Bohan Liu, Yujiao Deng, Feifei Yang, Wenjun Wang, Xixiang Lin, Liheng Yu, Haitao Pu, Peifang Zhang, Zongren Li, Qin Zhong, Qian Jia, Yao Li, Xiao Wang, Wei Chen, Daniel Burkhoff, Kunlun He   +16 more
doaj   +1 more source

Restricted spirometry and cardiometabolic comorbidities: results from the international population based BOLD study

Respiratory Research, 2022
Background Whether restricted spirometry, i.e. low Forced Vital Capacity (FVC), predicts chronic cardiometabolic disease is not definitely known. In this international population-based study, we assessed the relationship between restricted spirometry and
Katarzyna Kulbacka-Ortiz, Filip J. J. Triest, Frits M. E. Franssen, Emiel F. M. Wouters, Michael Studnicka, William M. Vollmer, Bernd Lamprecht, Peter G. J. Burney, Andre F. S. Amaral, Lowie E. G. W. Vanfleteren   +9 more
doaj   +1 more source

Atrial Tissue Pro‐Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B‐Type Natriuretic Peptide

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Atrial tissue fibrosis is linked to inflammatory cells, yet is incompletely understood. A growing body of literature associates peripheral blood levels of the antifibrotic hormone BNP (B‐type natriuretic peptide) with atrial fibrillation (AF).
Chris J. Watson, Nadezhda Glezeva, Stephen Horgan, Joe Gallagher, Dermot Phelan, Ken McDonald, Michael Tolan, John Baugh, Patrick Collier, Mark Ledwidge   +9 more
doaj   +1 more source

Pipersentan: A De Novo Synthetic Endothelin Receptor Antagonist that Inhibits Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension

Frontiers in Pharmacology, 2022
Background: Although major advances have been made in the pathogenesis and management of pulmonary arterial hypertension (PAH), the endothelin system is still considered to play a vital role in the pathology of PAH due to its vasoconstrictive action ...
Zeyu Zhang, Zeyu Zhang, Zeyu Zhang, Chunlei Liu, Chunlei Liu, Yongyi Bai, Xin Li, Xin Li, Xiaojian Gao, Xiaojian Gao, Xiaojian Gao, Chen Li, Chen Li, Ge Guo, Ge Guo, Si Chen, Mingzhuang Sun, Kang Liu, Yang Li, Kunlun He, Kunlun He   +20 more
doaj   +1 more source

Independent and combined effects of hypertension and diabetes on clinical outcomes in patients with COVID‐19: A retrospective cohort study of Huoshen Mountain Hospital and Guanggu Fangcang Shelter Hospital

The Journal of Clinical Hypertension, 2021
It is widely recognized that hypertension is one of the major risk factor for disease severity and mortality in patients with coronavirus disease 2019 (COVID‐19). However, type 2 diabetes mellitus (T2DM) and hypertension are frequent comorbid conditions,
Yuhui Sun, Xizhou Guan, Lijing Jia, Ning Xing, Liuquan Cheng, Bo Liu, Sibing Zhang, Kunlun He   +7 more
doaj   +1 more source