Objective: Although guidelines have recommended standardized drug treatment for heart failure (HF), there are still many challenges in making the correct clinical decisions due to the complicated clinical situations of HF patients.
Yongyi Bai +12 more
doaj +1 more source
Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]
Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H +22 more
core +2 more sources
‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A. +2 more
core +4 more sources
The relation between cardiac 123I-mIBG scintigraphy and functional response 1 year after CRT implantation [PDF]
Cardiac resynchronization therapy (CRT) is a disease-modifying therapy in patients with chronic heart failure (CHF). Current guidelines ascribe CRT eligibility on three parameters only: left ventricular ejection fraction (LVEF), QRS duration, and New ...
de Groot, J R +7 more
core +1 more source
Metabolic and cardiac adaptation to chronic pharmacologic blockade of facilitative glucose transport in murine dilated cardiomyopathy and myocardial ischemia [PDF]
GLUT transgenic and knockout mice have provided valuable insight into the role of facilitative glucose transporters (GLUTs) in cardiovascular and metabolic disease, but compensatory physiological changes can hinder interpretation of these models.
Heitmeier, Monique R. +6 more
core +2 more sources
Activity Theory Analysis of Heart Failure Self-Care [PDF]
The management of chronic health conditions such as heart failure is a complex process emerging from the activity of a network of individuals and artifacts.
Cornet, Victor +2 more
core +1 more source
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Wenbin Gao +36 more
doaj +1 more source
Duration of heart failure and the risk of atrial fibrillation: different mechanisms at different times? [PDF]
Chronic heart failure increases the risk of atrial fibrillation (AF), with the prevalence of AF paralleling the severity of heart failure.1 Factors that underlie this increased susceptibility to AF may include electrical, structural, and neurohumoral ...
A. C. Rankin +10 more
core +1 more source
Novel Targets in a High-Altitude Pulmonary Hypertension Rat Model Based on RNA-seq and Proteomics
High-altitude pulmonary hypertension (HAPH) is a complication arising from an inability to acclimatize to high altitude and is associated with high morbidity and mortality.
Xiang Xu +11 more
doaj +1 more source
Natriuretic Peptides in Chronic Heart Failure
Normal brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) levels are helpful in excluding chronic heart failure in the ambulatory setting, although they have been studied less well and possibly less accurately than in acute care.
Hans-Peter Brunner-La Rocca +1 more
doaj +1 more source

