Results 11 to 20 of about 1,871,268 (358)

Exercise intolerance and fatigue in chronic heart failure: is there a role for group III/IV afferent feedback? [PDF]

, 2020
Exercise intolerance and early fatiguability are hallmark symptoms of chronic heart failure. While the malfunction of the heart is certainly the leading cause of chronic heart failure, the patho-physiological mechanisms of exercise intolerance in these ...
Angius, Luca, Crisafulli, Antonio
core   +2 more sources

Atrial Tissue Pro‐Fibrotic M2 Macrophage Marker CD163+, Gene Expression of Procollagen and B‐Type Natriuretic Peptide

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Atrial tissue fibrosis is linked to inflammatory cells, yet is incompletely understood. A growing body of literature associates peripheral blood levels of the antifibrotic hormone BNP (B‐type natriuretic peptide) with atrial fibrillation (AF).
Chris J. Watson, Nadezhda Glezeva, Stephen Horgan, Joe Gallagher, Dermot Phelan, Ken McDonald, Michael Tolan, John Baugh, Patrick Collier, Mark Ledwidge   +9 more
doaj   +1 more source

Pipersentan: A De Novo Synthetic Endothelin Receptor Antagonist that Inhibits Monocrotaline- and Hypoxia-Induced Pulmonary Hypertension

Frontiers in Pharmacology, 2022
Background: Although major advances have been made in the pathogenesis and management of pulmonary arterial hypertension (PAH), the endothelin system is still considered to play a vital role in the pathology of PAH due to its vasoconstrictive action ...
Zeyu Zhang, Zeyu Zhang, Zeyu Zhang, Chunlei Liu, Chunlei Liu, Yongyi Bai, Xin Li, Xin Li, Xiaojian Gao, Xiaojian Gao, Xiaojian Gao, Chen Li, Chen Li, Ge Guo, Ge Guo, Si Chen, Mingzhuang Sun, Kang Liu, Yang Li, Kunlun He, Kunlun He   +20 more
doaj   +1 more source

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

New England Journal of Medicine, 2022
BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less.
S. Solomon, J. McMurray, B. Claggett, R. D. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, Akshay S. Desai, P. Jhund, J. Bělohlávek, C. Chiang, C. Borleffs, J. Comín-Colet, D. Dobreanu, J. Drożdż, J. Fang, M. Alcocer-Gamba, Waleed Al habeeb, Yaling Han, Jose Walter Cabrera Honorio, S. Janssens, T. Katova, M. Kitakaze, B. Merkely, E. O’Meara, J. Saraiva, S. Tereshchenko, J. Thierer, M. Vaduganathan, O. Vardeny, S. Verma, V. Pham, U. Wilderäng, Natalia Zaozerska, E. Bachus, D. Lindholm, Magnus Petersson, A. Langkilde   +41 more
semanticscholar   +1 more source

Independent and combined effects of hypertension and diabetes on clinical outcomes in patients with COVID‐19: A retrospective cohort study of Huoshen Mountain Hospital and Guanggu Fangcang Shelter Hospital

The Journal of Clinical Hypertension, 2021
It is widely recognized that hypertension is one of the major risk factor for disease severity and mortality in patients with coronavirus disease 2019 (COVID‐19). However, type 2 diabetes mellitus (T2DM) and hypertension are frequent comorbid conditions,
Yuhui Sun, Xizhou Guan, Lijing Jia, Ning Xing, Liuquan Cheng, Bo Liu, Sibing Zhang, Kunlun He   +7 more
doaj   +1 more source

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2012
Authors/Task Force Members: John J.V. McMurray (Chairperson) (UK)*, Stamatis Adamopoulos (Greece), Stefan D. Anker (Germany), Angelo Auricchio (Switzerland), Michael Bohm (Germany), Kenneth Dickstein (Norway), Volkmar Falk (Switzerland), Gerasimos ...
J. McMurray, S. Adamopoulos, S. Anker, A. Auricchio, M. Böhm, K. Dickstein, V. Falk, G. Filippatos, C. Fonseca, M. Gómez-Sánchez, T. Jaarsma, L. Køber, G. Lip, A. Maggioni, A. Parkhomenko, B. Pieske, B. Popescu, P. Rønnevik, F. Rutten, J. Schwitter, P. Seferovic, J. Stȩpińska, P. Trindade, A. Voors, F. Zannad, A. Zeiher, J. Bax, H. Baumgartner, C. Ceconi, V. Dean, C. Deaton, R. Fagard, C. Funck-Brentano, D. Hasdai, A. Hoes, P. Kirchhof, J. Knuuti, P. Kolh, T. McDonagh, C. Moulin, Ž. Reiner, U. Sechtem, P. Sirnes, M. Tendera, A. Torbicki, A. Vahanian, S. Windecker, L. A. Bonet, P. Avraamides, Hisham A. Ben Lamin, M. Brignole, A. Coca, Peter Cowburn, H. Dargie, P. Elliott, F. Flachskampf, Guido Francesco Guida, S. Hardman, B. Iung, B. Merkely, C. Mueller, J. Nanas, O. Nielsen, S. Ørn, J. Parissis, P. Ponikowski   +65 more
semanticscholar   +1 more source

What can we learn from SOCRATES: more questions than answers? [PDF]

, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

Physiological monitoring in the complex multimorbid heart failure patient - Conclusions. [PDF]

, 2019
Comorbidities are increasingly recognized as crucial components of the heart failure syndrome. Main specific challenges are polypharmacy, poor adherence to treatments, psychological aspects, and the need of monitoring after discharge.
Böhm, M, Coats, AJS, Kindermann, I, Rosano, G, Spoletini, I   +4 more
core   +1 more source

A Multi-Task Neural Network Architecture for Renal Dysfunction Prediction in Heart Failure Patients With Electronic Health Records

IEEE Access, 2019
Renal dysfunction, which is associated with bad clinical outcomes, is one of the most common complications of heart failure (HF). Timely prediction of renal dysfunction can help medical staffs intervene early to avoid catastrophic consequences.
Binhua Wang, Yongyi Bai, Zhenjie Yao, Jiangong Li, Wei Dong, Yanhui Tu, Wanguo Xue, Yaping Tian, Yifei Wang, Kunlun He   +9 more
doaj   +1 more source

F2RL3 Methylation in the Peripheral Blood as a Potential Marker for the Detection of Coronary Heart Disease: A Case-Control Study

Frontiers in Genetics, 2022
Background and Aims: Previous work has shown the association between blood-based methylation of coagulation factor II receptor-like 3 gene (F2RL3) and cardiovascular mortality in Caucasians.
Xiaojing Zhao, Xiaojing Zhao, Liya Zhu, Qiming Yin, Zhenguo Xu, Zhenguo Xu, Qian Jia, Qian Jia, Rongxi Yang, Kunlun He, Kunlun He   +10 more
doaj   +1 more source