Results 41 to 50 of about 1,218,074 (349)

Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts

Frontiers in Cell and Developmental Biology, 2019
Fusobacterium nucleatum (F. nucleatum) is a crucial periodontal pathogen and human gingival fibroblasts (GFs) are the first line of defense against oral pathogens.
Wenyan Kang, Wenyan Kang, Zhilong Jia, Zhilong Jia, Di Tang, Xiaojing Zhao, Xiaojing Zhao, Jinlong Shi, Qian Jia, Qian Jia, Kunlun He, Kunlun He, Qiang Feng, Qiang Feng   +13 more
doaj   +1 more source

Elevated circulating levels of tumor necrosis factor in severe chronic heart failure.

New England Journal of Medicine, 1990
BACKGROUND AND METHODS Although cachexia often accompanies advanced heart failure, little is known about the causes of the cachectic state. To assess the potential role of tumor necrosis factor in the pathogenesis of cardiac cachexia, we measured serum ...
B. Levine, J. Kalman, L. Mayer, H. Fillit, M. Packer   +4 more
semanticscholar   +1 more source

Distinct Circulating Expression Profiles of Long Noncoding RNAs in Heart Failure Patients With Ischemic and Nonischemic Dilated Cardiomyopathy

Frontiers in Genetics, 2019
Ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM), with distinct long-term prognosis and responses to treatment, are two major problems that lead to heart failure (HF) ultimately. In this study, we investigated the long noncoding RNA (lncRNA)
Fang Lin, Fang Lin, Fang Lin, Xin Gong, Ping Yu, Aixue Yue, Qingshu Meng, Qingshu Meng, Qingshu Meng, Liang Zheng, Liang Zheng, Liang Zheng, Tian Chen, Lu Han, Lu Han, Hao Cao, Jianhong Cao, Xiaoting Liang, Xiaoting Liang, Hao Hu, Yuan Li, Yuan Li, Zhongmin Liu, Zhongmin Liu, Zhongmin Liu, Zhongmin Liu, Zhongmin Liu, Zhongmin Liu, Xiaohui Zhou, Xiaohui Zhou, Xiaohui Zhou, Huimin Fan, Huimin Fan, Huimin Fan, Huimin Fan, Huimin Fan, Huimin Fan   +36 more
doaj   +1 more source

Creation of registers as one of the mechanisms for improving medical care for patients with chronic heart failure. Problem state

Терапевтический архив, 2023
The annual mortality of patients with clinically pronounced symptoms of chronic heart failure in the Russian Federation reaches 2629%, i.e., from 880 to 986 thousand patients with heart failure die in the country in one year, which is comparable to the ...
Oleg M. Reitblat, Anna A. Airapetian, Natalia V. Lazareva, Evgeny M. Mezhonov, Evgeny V. Sorokin, Iuliia Sh. Prints, Zoya N. Blankova, Olga N. Svirida, Fail T. Ageev, Igor V. Zhirov, Sergey N. Tereshchenko, Sergey A. Boytsov   +11 more
doaj   +1 more source

Anemia in Chronic Heart Failure [PDF]

Congestive Heart Failure, 2009
Anemia is frequently observed in patients with chronic heart failure and is increasingly recognized as an important and treatable condition. The present review will summarize the current knowledge of the prevalence, causative factors, and pathophysiologic correlates of anemia in chronic heart failure.
Maria Anastasiou-Nana, Konstantinos Malliaras, John N. Nanas, Stavros G. Drakos   +3 more
openaire   +3 more sources

Mechanism of tonifying-kidney Chinese herbal medicine in the treatment of chronic heart failure

Frontiers in Cardiovascular Medicine, 2022
According to traditional Chinese medicine (TCM), chronic heart failure has the basic pathological characteristics of “heart-kidney yang deficiency.” Chronic heart failure with heart- and kidney-Yang deficiency has good overlap with New York Heart ...
Lizhen Chen, Dayun Yu, Shuang Ling, Jin-Wen Xu   +3 more
doaj   +1 more source

JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure　- Digest Version.

Circulation Journal, 2019
J-STAGE Advance Publication released online September 10, 2019 Mailing address: Scientific Committee of the Japanese Circulation Society, 18F Imperial Hotel Tower, 1-1-1 Uchisaiwai-cho, Chiyoda-ku, Tokyo 100-0011, Japan. E-mail: meeting@j-circ.or.jp This
H. Tsutsui, M. Isobe, Hiroshi Ito, Hiroshi Ito, K. Okumura, M. Ono, M. Kitakaze, K. Kinugawa, Y. Kihara, Y. Goto, I. Komuro, Y. Saiki, Yoshihiko Saito, Y. Sakata, N. Sato, Y. Sawa, A. Shiose, W. Shimizu, H. Shimokawa, Y. Seino, K. Node, T. Higo, A. Hirayama, M. Makaya, T. Masuyama, T. Murohara, S. Momomura, M. Yano, K. Yamazaki, Kazuhiro Yamamoto, T. Yoshikawa, M. Yoshimura, Masatoshi Akiyama, T. Anzai, S. Ishihara, T. Inomata, T. Imamura, Y. Iwasaki, T. Ohtani, K. Onishi, T. Kasai, Mahoto Kato, M. Kawai, Y. Kinugasa, S. Kinugawa, T. Kuratani, Shigeki Kobayashi, Y. Sakata, Atsushi Tanaka, K. Toda, T. Noda, Kotaro Nochioka, M. Hatano, T. Hidaka, T. Fujino, S. Makita, O. Yamaguchi, Uichi Ikeda, Takeshi Kimura, S. Kohsaka, M. Kosuge, M. Yamagishi, A. Yamashina   +62 more
semanticscholar   +1 more source

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

New England Journal of Medicine, 2022
BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less.
S. Solomon, J. McMurray, B. Claggett, R. D. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, Akshay S. Desai, P. Jhund, J. Bělohlávek, C. Chiang, C. Borleffs, J. Comín-Colet, D. Dobreanu, J. Drożdż, J. Fang, M. Alcocer-Gamba, Waleed Al habeeb, Yaling Han, Jose Walter Cabrera Honorio, S. Janssens, T. Katova, M. Kitakaze, B. Merkely, E. O’Meara, J. Saraiva, S. Tereshchenko, J. Thierer, M. Vaduganathan, O. Vardeny, S. Verma, V. Pham, U. Wilderäng, Natalia Zaozerska, E. Bachus, D. Lindholm, Magnus Petersson, A. Langkilde   +41 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Cardiorenal relationships in patients with chronic heart failure with preserved ejection fraction

Лечащий Врач, 2023
The combination of heart and kidney diseases caused by chronic heart failure and aggravated by kidney damage, called cardiorenal syndrome, is increasingly recognized as a critical pathological unit, leading to a worsening of the prognosis in patients ...
Yu. N. Panina, V. I. Vishnevsky
doaj   +1 more source