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The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment.
Jang, Jae Young, Chung, Raymond T.
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Chronic hepatitis C: future treatment
Astrid Wendt, Xavier Adhoute, Paul Castellani, Valerie Oules, Christelle Ansaldi, Souad Benali, Marc BourlièreDepartment of Hepato-Gastroenterology, Hôpital Saint-Joseph, Marseille, FranceAbstract: The launch of first-generation protease ...
Wendt A +6 more
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Treatment of chronic hepatitis C genotype 1 with triple therapy comprising telaprevir or boceprevir [PDF]
Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma worldwide. Two first-generation protease inhibitors, telaprevir and boceprevir, have recently been approved for the treatment of
Darius Moradpour +2 more
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Hepatitis C (HCV) is a common viral infection of the liver. It affects approximately 1.6% of the US population. Screening in the appropriate populations is essential as signs and symptoms of the disease are generally absent. In addition, there are multiple new treatments for HCV which are extremely effective and very well tolerated. In this chapter, we
Sadia Iqbal +5 more
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Hepatitis C infection is a treatable disease.1 Generally, people with chronic hepatitis C are relatively asymptomatic but risk progression over time to cirrhosis and its complications. Combination antiviral therapy with pegylated interferon and ribavirin achieves sustained virological response rates of 42-80% depending on genotype.2 In August 2006 the ...
Kosh, Agarwal +2 more
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The burden of hepatitis C virus in the world, China, India, and the United States from 1990 to 2019
Background and aimHepatitis C virus infection can lead to an enormous health burden worldwide. Investigating the changes in HCV-related burden between different countries could provide inferences for disease management.
Jia Yang +7 more
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Different profiles of neurocognitive impairment in patients with hepatitis B and C virus infections
The direct impact of chronic hepatitis B and hepatitis C on neurocognition remains elusive due to the frequent comorbidities, and the domains of the neurocognitive functions affected have rarely been investigated comprehensively.
Chun-Hsiang Tan +9 more
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Quality of life in patients with chronic hepatitis C [PDF]
Introduction. Hepatitis C virus often causes chronic liver disease reducing physical, mental and social functions in these patients. Objective. The aim of this investigation was analysis of the quality of life in chronic hepatitis C patients compared ...
Pavić Slađana +3 more
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Clinical and psychopathological features of the course and outcome of the first psychotic episode.
Recently it has been established that cytokines are involved in the regulation of the body’s defense reactions in response to a pathogen and form an independent system for regulating homeostasis.
Yuri Bazhora +4 more
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A CURE FOR RECENTLY ACQUIRED HEPATITIS C [PDF]
Chronic hepatitis C is a global health threat. Most individuals infected with the hepatitis C virus (HCV) will inevitably progress to chronic infection, leading to cirrhosis and hepatocellular carcinoma.
Radka Komitova +2 more
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