Decrease in health-related quality of life associated with awareness of hepatitis C virus infection among people who inject drugs in Scotland [PDF]
, 2013 Chronic hepatitis C virus (HCV) infection can significantly reduce health-related quality of life (QoL), but it is not clear if reduction is associated with the infection or with being aware of one's infection status.
Hutchinson, Sharon +6 more
core +4 more sources
, 2004 We examined correlates of antinuclear antibody (ANA) positivity (ANA+) in individuals with chronic hepatitis C virus (HCV) infection and the effect of positivity on clinical outcome of HCV. Pretreatment sera from 645 patients from three centres in Sweden
Marshall, S +22 more
core +1 more source
Adding low-dose antidepressants to interferon alpha treatment for chronic hepatitis C improved psychiatric tolerability in a patient with schizoaffective psychosis [PDF]
, 2000 Treatment of chronic hepatitis C with interferon alpha (IFN-alpha) is relatively contraindicated in patients with psychiatric disorders because of possible severe psychiatric side effects.
Amann, B. +5 more
core +1 more source
Costs of Treatment, Follow-Up, and Complications of Chronic Hepatitis B and Hepatitis C Infections
Balkan Medical Journal, 2013 Background: Few studies have addressed the indirect costs of chronic hepatitis B and C, and none has assessed the real costs of these conditions, including indirect costs caused by loss of work, in Turkey. Aims: This study therefore analysed the costs of
Fatma Banu Karahasanoğlu +3 more
doaj +1 more source
Журнал инфектологии, 2014 Blood markers of endothelial activation (sVCAM-1, vWF: Ag) in patients with chronic hepatitis C in the presence of insulin resistance, metabolic syndrome and its components had been evaluated.
T. V. Antonova +2 more
doaj +1 more source
Eltrombopag in chronic hepatitis C
World Journal of Gastroenterology, 2014 Chronic hepatitis C is a public health problem worldwide. Unfortunately, not all patients may benefit from antiviral therapy due to thrombocytopenia. Its causes are represented by portal hypertension and platelet sequestration in the spleen, decreased serum levels or activity of thrombopoietin, the bone marrow suppression induced by hepatitis C virus ...
Romeo-Gabriel, Mihăilă +1 more
openaire +2 more sources
Hepatitis C prevalence in Denmark -an estimate based on multiple national registers
BMC Infectious Diseases, 2012 Background A national survey for chronic hepatitis C has not been performed in Denmark and the prevalence is unknown. Our aim was to estimate the prevalence of chronic hepatitis C from public registers and the proportion of these patients who received ...
Christensen Peer +8 more
doaj +1 more source
Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]
, 2011 Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Nashwa Abousamra +5 more
core
Interferon signalling in the liver : implications for the natural course and therapy of hepatitis C [PDF]
, 2012 Hepatitis C virus is a global health concern, estimated to infect 2-3% of the world's population. Inter-individual differences in the course of infection and response to therapy, highlighted by recent genomewide association studies, point to the crucial ...
Makowska, Zuzanna
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source