Results 41 to 50 of about 1,109,482 (395)

Raised serum transaminases during treatment with pegylated interferon for chronic hepatiti C [PDF]

, 2016
Introduction : Serum transaminases rose significantly in 7 patients with chronic hepatitis C, genotypes 2 and 3, who were treated with pegylated interferon and ribavirin. Methods : 219 patients with chronic hepatitis C, genotypes 2 and 3, were treated
Datta, S., Mandalou, P., Mills, P.R., Spence, E.   +3 more
core   +1 more source

CHRONIC HEPATITIS “C”;

The Professional Medical Journal, 2013
OBJECTIVE: To find spectrum of various dermatological manifestations during hepatitis “C” virus infection in localpopulation of hyderabad. METHODS: This descriptive study was conducted in medicine department of Isra University HospitalHyderabad from January 2011 to June 2012. A total of 325 anti-HCV positive patients were enrolled.
ATIF SITWAT HAYAT, MUHAMMAD ADNAN BAWANY, TARIQ ZAFAR SHAIKH, Adnan Ali Khahro, Shireen Rahat Khanzada   +4 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Treatment of Chronic Hepatitis C with High Dose Interferon Therapy Experience From Pertamina Central Hospital Jakarta [PDF]

, 2002
Background: Until several years ago, interferon alfa was the only drug with proven benefit for the treatment of chronic Hepatitis C. Several therapy categories such as fixed-dose regimens, induction-dose regimens and escalation-dose regimens are already ...
Simanjuntak, W. (Waldemar)
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The influence of hepatic steatosis on the success of antiviral therapy for chronic hepatitis C [PDF]

Vojnosanitetski Pregled, 2017
Background/Aim. Chronic hepatitis C and liver steatosis often appear simultaneously in the same person, and steatosis can lead to worsening of liver disease and reducing the success of the treatment of chronic hepatitis C.
Preveden Tomislav, Ružić Maja, Pete Maria   +2 more
doaj   +1 more source

Interferon alfa subtypes and levels of type I interferons in the liver and peripheral mononuclear cells in patients with chronic hepatitis C and controls [PDF]

, 1999
Viral infections stimulate the transcription of interferon type I, which includes IFN-alfa (IFN-alpha) (13 subtypes) and IFN-beta (a single substance).
Boya, P. (Patricia), Castelruiz, Y. (Yurdana), Civeira, M.P. (María Pilar), Larrea, E. (Esther), Prieto, J. (Jesús)   +4 more
core   +1 more source

Breakthroughs in hepatitis C research: from discovery to cure

Nature reviews: Gastroenterology & hepatology, 2022
In the 1970s, an unknown virus was suspected for documented cases of transfusion-associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious transmissible agent was identified and named hepatitis C virus (HCV) and, soon ...
M. Manns, B. Maasoumy
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]

, 2018
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core   +1 more source