Results 101 to 110 of about 2,450,341 (179)

Measurement of IL-12 (p40, p35), IL-23p19, and IFN-gamma mRNA in Duodenal Biopsies of Cats with Inflammatory Enteropathy

, 2014
BackgroundDietary hypersensitivity and inflammatory bowel disease (IBD) are important causes of chronic vomiting and diarrhea in cats. IL-23 has been recently found to be a key factor in the immunopathogenesis of IBD in humans but the involvement in IBD ...
Gruffydd-Jones, T. J., Peters, I. R., Waly, N. E., Bailey, M., Day, M. J., Stokes, C. R.   +5 more
core   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Canine adipose-derived mesenchymal stromal cells inhibit the growth of canine hematologic malignancy cell lines

Regenerative Therapy
Introduction: Intestinal lymphoma may be latent in some dogs with chronic inflammatory enteropathy. Mesenchymal stromal cells (MSCs) have potential therapeutic applications for refractory chronic inflammatory enteropathy, but their impact on the ...
Yuyo Yasumura, Takahiro Teshima, Tomokazu Nagashima, Masaki Michishita, Hiroki Shigechika, Yoshiaki Taira, Ryohei Suzuki, Hirotaka Matsumoto   +7 more
doaj   +1 more source

Review Article: Accelerating Coeliac Disease Clinical Trials—Beyond Celiac Meeting With Industry, Academics, Patients and the FDA

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 890-896, October 2026.
A 2024 multi‐stakeholder meeting examined how to accelerate coeliac disease drug trials, highlighting key considerations in endpoint selection, symptom–histology alignment and feasibility. Progress requires patient‐centred trials showing symptomatic and intestinal improvement, appropriate gluten challenge, and early regulatory engagement, including ...
Lisa M. Fahey, Robert Anderson, Edwin Liu, Joseph A. Murray, Marie E. Robert, Jocelyn Anne Silvester, Kate Avery, Nelson Cheinquer, Kristie Grebe, Bhargav Tulabandula, Daniel A. Leffler, Beyond Celiac Coalition   +11 more
wiley   +1 more source

Chronic Enteropathy In Canines: Prevalence, Impact And Management Strategies

Veterinary Medicine: Research and Reports, 2019
Julien Rodolphe Samuel Dandrieux , Caroline Sarah Mansfield Department of Veterinary Clinical Sciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Werribee, Victoria, AustraliaCorrespondence ...
Dandrieux JRS, Mansfield CS
doaj  

Successful Management of a Dog with Protein-Losing Enteropathy and Concurrent Protein-Losing Nephropathy with Repeated Fecal Microbiota Transplantation

Pets
Protein-losing enteropathy (PLE) is a spectrum of gastrointestinal disorders in which protein loss occurs through the gastrointestinal tract. One of the underlying causes is chronic inflammatory enteropathy (CIE).
Alexander Schreiber, Chih-Chun Chen, Jan S. Suchodolski, Betty Chow   +3 more
doaj   +1 more source

Atypical hemolytic uremic syndrome in a patient with protein-losing enteropathy

Journal of International Medical Research, 2019
Atypical hemolytic uremic syndrome (aHUS) is an ultra-rare disease induced by many triggers, all of which produce a common end phenotype of microangiopathic hemolysis and thrombotic microangiopathy.
Ramy M. Hanna, Huma Hasnain, Lama Abdelnour, Beshoy Yanny, Richard M. Burwick   +4 more
doaj   +1 more source

Faecal Microbiota Transplantation Reduces Lesion Severity and Medication Use in Canine Atopic Dermatitis: A Randomised, Placebo‐Controlled, Double‐Blinded Clinical Trial

Veterinary Dermatology, Volume 37, Issue 5, Page 735-744, October 2026.
Background: Faecal microbiota transplantation (FMT) is an established therapy for gastrointestinal disease, yet its role in canine atopic dermatitis (cAD) remains unclear. Hypothesis/Objectives: We hypothesised that adjunctive FMT improves clinical severity and reduces symptomatic medication use in dogs with cAD.
Vera Felten, Erin Asley West, Franco Martini, Claude Favrot, Stefan Unterer, Jan Suchodolski, Michael Scharl, Harald Renz, Nina Maria Fischer, Ana Rostaher   +9 more
wiley   +1 more source

Study protocol to investigate the effects of testosterone therapy as an adjunct to exercise rehabilitation in hypogonadal males with chronic heart failure [PDF]

, 2006
Testosterone deficiency is a common occurrence in men with chronic heart failure (CHF) and may underpin features of advanced disease, including reduced skeletal muscle mass and fatigue.
Mathur, Atish, Zwierska, Irena, Saxton, John, Saxton, John M, Channer, Kevin S, Channer, Kevin   +5 more
core   +1 more source

Case Report: Monoclonal gammopathy associated enteropathy: a potential MGCS related phenotype with response to plasma cell directed therapy

Frontiers in Medicine
BackgroundChronic inflammatory diarrhea with preserved mucosal architecture remains diagnostically challenging when inflammatory bowel disease, autoimmune enteropathy, and infection are excluded.
Guo Chen, Li He, Yuan Yuan Chen, Peng Yang, Jing Tan   +4 more
doaj   +1 more source