Results 51 to 60 of about 2,522,978 (266)

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

Advanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li, Kelly Yichen Li, Chiara Nicoletti, Stephen Kwok‐Wing Tsui, Pier Lorenzo Puri, Qin Cao, Kevin Y. Yip   +6 more
wiley   +1 more source

Small cell lung cancer associated small bowel obstruction, a diagnostic conundrum: A case report

Clinical Case Reports
Key clinical message Small cell lung cancer (SCLC), a neuroendocrine aggressive subtype of lung cancer, is associated with paraneoplastic disorders in about 9% of patients.
Mohammad Ayoub, Mohannad Natheef AbuHaweeleh, Nabil Mahmood, Colin Clelland, Malak Mohammad Ayoub, Harman Saman   +5 more
doaj   +1 more source

Severe chronic bowel obstruction associated with brown bowel syndrome

SAGE Open Medical Case Reports, 2020
A 61-year-old alcoholic male with history of cholecystectomy presented with a 20-year history of recurrent bowel obstruction and a 30 lb weight loss. After numerous attempts at conservative management, exploratory laparotomy was performed, which showed ...
Yan Chen Wongworawat, Robert Propst, Anwar Raza, Bonnie Rohweller, Lourdes Swentek, Craig William Zuppan, Camilla Cobb   +6 more
doaj   +1 more source

Pediatric intestinal pseudo-obstruction: Role of histopathology

Journal of Pediatric Surgery Case Reports, 2020
Pediatric intestinal pseudo-obstruction (PIPO) is a rare and debilitating clinical disorder characterized by gastrointestinal motility dysfunction, resulting in symptoms suggestive of total or partial intestinal obstruction in the absence of any lumen ...
Ana Luiza Melo dos Santos, Rafaela Wander Almeida Braga, Heinrich Bender Kohnert Seidler, Rodrigo Pinheiro de Abreu Miranda, Ivânia Itália Teixeira Salvador, Elisa de Carvalho   +5 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Chronic intestinal pseudo-obstruction due to

, 2018
We report a case of chronic intestinal pseudo-obstruction due to a generalized visceral autonomic neuropathy in an immune-competent patient infected ...
Helmstetter, Nicholas, Greenberg, Joshua C, Greenberg, Jenna   +2 more
core   +1 more source

Spontaneous transverse colon volvulus in a patient with Duchenne muscular dystrophy: An unreported complication

Radiology Case Reports, 2023
A 22-year-old male patient with Duchenne muscular dystrophy (DMD) and chronic constipation presents to the emergency room with severe abdominal pain and hive closed to feces and gas.
Pietro Pitrone, MD, Antonino Cattafi, MD, Francesca Magnani, MD, Maria Ludovica Carerj, MD, Italo Giuseppe Bellone, MD, Giuseppe Nirta, MD, Enrico Monsù, MD, Dora Bonanno, MD, Renato Trimarchi, MD, Alessandro La Face, MD, Maria Adele Marino, MD, Carmelo Sofia, MD   +11 more
doaj   +1 more source

Caecal volvulus in a patient with chronic intestinal pseudo-obstruction

, 2011
Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder characterised by recurrent symptoms and signs of intestinal obstruction without an underlying mechanical cause.
C El-Khatib, M Tatterton
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source