Results 61 to 70 of about 9,190 (242)

Chronic Intestinal Pseudo-Obstruction and Lymphoproliferative Syndrome as a Novel Phenotype Associated With Tetratricopeptide Repeat Domain 7A Deficiency

Frontiers in Immunology, 2019
Mutations in the tetratricopeptide repeat domain 7A (TTC7A) gene cause very early onset inflammatory bowel diseases (VOIBD) or multiple intestinal atresia associated with immune deficiency of various severities, ranging from combined immune deficiency to
Marie-Thérèse El-Daher, Marie-Thérèse El-Daher, Julie Lemale, Julie Bruneau, Julie Bruneau, Claire Leveau, Claire Leveau, Frédéric Guerin, Frédéric Guerin, Nathalie Lambert, Jean-Sébastien Diana, Bénédicte Neven, Fernando E. Sepulveda, Fernando E. Sepulveda, Fernando E. Sepulveda, Aurore Coulomb-L'Hermine, Thierry Molina, Thierry Molina, Capucine Picard, Capucine Picard, Capucine Picard, Alain Fischer, Alain Fischer, Alain Fischer, Geneviève de Saint Basile, Geneviève de Saint Basile, Geneviève de Saint Basile   +26 more
doaj   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

Caring for the Technology Dependent Child – a Case Study

Nursing Praxis in Aotearoa New Zealand, 1998
Matthew is six years old and is an identical twin.  He and his brother Sam were born prematurely and are the first children of Kay and Robert.  The boys also have a younger sister, Bridget.  Matthew has chronic idiopathic intestinal pseudo-obstruction, a
Taima Campbell
doaj  

Paraneoplastic syndrome with intestinal pseudo-obstruction in a patient with small cell lung carcinoma: a case report and literature review

Journal of International Medical Research
Paraneoplastic chronic intestinal pseudo-obstruction (CIPO) is a rare manifestation associated with small cell lung carcinoma and other malignancies. In this report, we present a challenging case involving a 60-year-old man with small cell lung carcinoma
Xiao-Jun Ren, Zhao-Hong Shi, Ying-Xia Cheng, Yun Luo   +3 more
doaj   +1 more source

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

A report of chronic intestinal pseudo-obstruction related to systemic lupus erythematosus

Open Medicine, 2018
Chronic intestinal pseudo-obstruction (CIPO) is a functional gastrointestinal disorder with symptoms of ileus. CIPO can either be idiopathic or secondary to other diseases such as systemic lupus erythematosus (SLE).
Wang Ruiqiang, Zheng Bowen, Wang Biyue, Ma Pupu, Chen Fengmei, Tang Lin   +5 more
doaj   +1 more source

Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and EpigenomicsSummary

Cellular and Molecular Gastroenterology and Hepatology, 2019
Background & Aims: A generalized human pacemaking syndrome, chronic atrial and intestinal dysrhythmia (CAID) (OMIM 616201), is caused by a homozygous SGO1 mutation (K23E), leading to chronic intestinal pseudo-obstruction and arrhythmias.
Jessica Piché, Natacha Gosset, Lisa-Marie Legault, Alain Pacis, Andrea Oneglia, Maxime Caron, Philippe Chetaille, Luis Barreiro, Donghai Liu, Xioyan Qi, Stanley Nattel, Séverine Leclerc, Mélanie Breton-Larrivée, Serge McGraw, Gregor Andelfinger, Gregor Andelfinger, Jeroen Bakkers, Bart Loeys, Michel Pucéat   +18 more
doaj   +1 more source

Myotonic dystrophy type 1 and pseudo-obstruction in a child with smooth muscle α-actin deficiency and eosinophilic myenteric plexitis

The Turkish Journal of Gastroenterology, 2018
Myotonic dystrophy (MD) frequently involves the gastrointestinal tract, where it can manifest as chronic intestinal pseudo-obstruction (CIPO), particularly in adults. This manifestation is quite uncommon in children.
Gloria Pelizzo, Valeria Calcaterra, Vincenzo Villanacci, Giovanni Battista Mura, Gabrio Bassotti   +4 more
doaj   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Chronic intestinal pseudo-obstruction associated with enteric ganglionitis in a Persian cat

Journal of Feline Medicine and Surgery Open Reports, 2016
Case summary A 7-year-old neutered male Persian cat was presented for acute vomiting and inappetence. Physical examination revealed severe abdominal distension.
Jeremy Mortier, Estelle Elissalt, Sophie Palierne, Marie Odile Semin, Maxence Delverdier, Armelle Diquélou   +5 more
doaj   +1 more source