Results 91 to 100 of about 2,747,113 (394)

Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]

, 2018
Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean, Halliday, Christopher, Jahagirdar, Ravi, Johansson, Jan O, Kalantar-Zadeh, Kamyar, Kulikowski, Ewelina, Robson, Richard, Stotz, Stephanie C, Sweeney, Michael, Tsujikawa, Laura M, Wasiak, Sylwia, Wong, Norman C   +11 more
core   +2 more sources

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Telomere Attrition in Chronic Kidney Diseases [PDF]

, 2023
Tina Levstek, Katarina Trebušak Podkrajšek   +1 more
openalex   +1 more source

Managing the cardiovascular complications of chronic kidney disease [PDF]

, 2008
Patients with chronic kidney disease have risk factors for cardiovascular disease which are additional to those found in the general population. Many patients will die of cardiovascular disease before they require dialysis for their kidney disease. While
Johnson, David W., Tan, Ken-Soon
core   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Emphysematous pyelonephritis in a diabetic child: a case report and review of the literature

Journal of Medical Case Reports
Introduction Emphysematous pyelonephritis is a life-threatening condition characterized by gas accumulation within the kidney and the surrounding tissues, often resulting in tissue necrosis.
Behnaz Bazargani, Mastaneh Moghtaderi, Hassan Esfandiary, Fatemeh Ghanbarian, Noosha Samieefar   +4 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Asuhan Keperawatan Pada Tn. S Dengan Gangguan Sistem Perkemihan: Chronic Kidney Disease Di Ruang Gladiol Atas Rumah Sakit Umum Daerah Sukoharjo [PDF]

, 2015
Background : An increasingly consumerist attitudes of humans towards food containing foreign substance harmful to the body the more damning work of the kidney causing disease chronic kidney disease.
, Fahrun Nur Rosid, S.Kep., Ns., M.Kes ., LISTIANI, IDA   +1 more
core  

Gout and risk of chronic kidney disease and nephrolithiasis meta-analysis of observational studies [PDF]

, 2015
ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis.
Belcher, J, Mallen, CD, Roddy, E
core   +2 more sources

Retrospective analysis of crescent score in clinical prognosis of IgA nephropathy

Open Medicine, 2022
The scoring of crescents (Cs) was recently added to the Oxford classification for IgA nephropathy (IgAN). Because of the short-term use of the C score in clinical practice, its validity and applicability need to be verified. We, retrospectively, analyzed
Chen Ying, Yang Yiya, Liang Yumei, Liu Manting, Xiao Wei, Hu Xiaofang   +5 more
doaj   +1 more source