Results 21 to 30 of about 2,456,607 (422)

Efficacy of rituximab therapy in children with nephrotic syndrome: a 10-year experience from an Iranian pediatric hospital

open access: yesBMC Pediatrics, 2022
Background There are controversy results in the optimal management of children with steroid-dependent and steroid-resistant nephrotic syndrome (SDNS, SRNS).
Behnaz Bazargani   +8 more
doaj   +1 more source

Synergistic effect between the KCNQ1 haplotype and alcohol consumption on the development of type 2 diabetes mellitus in Korean cohorts

open access: yesScientific Reports, 2021
Potassium voltage-gated channel subfamily Q member 1 (KCNQ1) is one of the strongest susceptibility genes for type 2 diabetes mellitus (T2DM). Association studies between KCNQ1 genetic variants and T2DM have been reported. The multifactorial disease T2DM
Ji Young Park   +4 more
doaj   +1 more source

Chronic kidney disease:Insights from social and genetic epidemiology [PDF]

open access: yes, 2020
Chronic kidney disease is a major global health burden, caused by the complex interplay between environmental and genetic factors. The results in this thesis provide valuable insights into these causes. First, I corroborate the existence of socioeconomic
Thio, C. H. L.
core   +2 more sources

Chronic Kidney Disease [PDF]

open access: yesAmerican Journal of Kidney Diseases, 2007
A 68 year old man sees you after you sent him a letter saying that the results of blood tests done over the past year to monitor hypertension show that he has chronic kidney disease (CKD). He is worried, as he thought that high blood pressure was his only medical problem. Useful resources Department of Health. The national service framework for
Eleanor, Lederer, Rosemary, Ouseph
openaire   +5 more sources

The effect of the association between CETP variant type and alcohol consumption on cholesterol level differs according to the ALDH2 variant type

open access: yesScientific Reports, 2022
Alcohol consumption is associated with a high increased lipid profile and this association may depend on genetic risk factors. In this study, we aimed to assess the effects of genetic variation associated with alcohol consumption on lipid profiles using ...
Min-Gyu Yoo   +3 more
doaj   +1 more source

Hypertension Management in Patients with Chronic Kidney Disease [PDF]

open access: yes, 2022
Hypertension and chronic kidney disease are closely linked. Patients with chronic kidney disease have hypertension almost universally and uncontrolled hypertension accelerates the decline in kidney function. The pathophysiology of hypertension in chronic
Hebert, Sean A, Ibrahim, Hassan N
core   +2 more sources

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.

open access: yesNew England Journal of Medicine, 2020
BACKGROUND Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced albuminuria in short-term trials involving patients with chronic kidney disease (CKD) and type 2 diabetes.
G. Bakris   +10 more
semanticscholar   +1 more source

ACE2 deficiency exacerbates obesity-related glomerulopathy through its role in regulating lipid metabolism

open access: yesCell Death Discovery, 2022
Obesity-related glomerulopathy is a secondary glomerular disease and its incidence has been increased globally in parallel with the obesity epidemic. ORG emerged as a growing cause of end-stage renal disease in recent years.
Yin-Yin Chen   +5 more
doaj   +1 more source

Diabetes Management in Chronic Kidney Disease: A Consensus Report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO)

open access: yesDiabetes Care, 2022
People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent clinical trials support new approaches to treat diabetes and CKD.
I. D. de Boer   +8 more
semanticscholar   +1 more source

Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis

open access: yesArthritis Research & Therapy, 2022
Background Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions.
Ning An   +11 more
doaj   +1 more source

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