Results 21 to 30 of about 2,747,113 (394)
Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes.
New England Journal of Medicine, 2020 BACKGROUND Finerenone, a nonsteroidal, selective mineralocorticoid receptor antagonist, reduced albuminuria in short-term trials involving patients with chronic kidney disease (CKD) and type 2 diabetes.
G. Bakris +10 more
semanticscholar +1 more source
Circulation Research, 2023 The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and regulating vascular integrity. In patients with chronic kidney disease, protective endothelial cell functions are impaired due to the proinflammatory, prothrombotic ...
C. Baaten, Sonja Vondenhoff, H. Noels
semanticscholar +1 more source
Climate change and the kidney [PDF]
, 2019 The worldwide increase in temperature has resulted in a marked increase in heat waves (heat extremes) that carries a markedly increased risk for morbidity and mortality.
Butler-Dawson, Jaime +12 more
core +1 more source
BMC Pediatrics, 2022 Background There are controversy results in the optimal management of children with steroid-dependent and steroid-resistant nephrotic syndrome (SDNS, SRNS).
Behnaz Bazargani +8 more
doaj +1 more source
Is “chronic kidney disease” a disease? [PDF]
Journal of Evaluation in Clinical Practice, 2018 AbstractSeveral philosophers of medicine have attempted to answer the question “what is disease?” In current clinical practice, an umbrella term “chronic kidney disease” (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end‐stage renal disease requiring transplant or dialysis to ...
Smart, B, Stevens, R, Verbakel, J
openaire +3 more sources
Scientific Reports, 2021 Potassium voltage-gated channel subfamily Q member 1 (KCNQ1) is one of the strongest susceptibility genes for type 2 diabetes mellitus (T2DM). Association studies between KCNQ1 genetic variants and T2DM have been reported. The multifactorial disease T2DM
Ji Young Park +4 more
doaj +1 more source
Global Prevalence of Chronic Kidney Disease – A Systematic Review and Meta-Analysis
PLoS ONE, 2016 Chronic kidney disease (CKD) is a global health burden with a high economic cost to health systems and is an independent risk factor for cardiovascular disease (CVD).
N. Hill +6 more
semanticscholar +1 more source
Association between urinary sodium, creatinine, albumin, and long term survival in chronic kidney disease [PDF]
, 2014 Dietary sodium intake is associated with hypertension and cardiovascular risk in the general population. In patients with chronic kidney disease, sodium intake has been associated with progressive renal disease, but not independently of proteinuria.
Fox, Jonathan G. +6 more
core +1 more source
Bisphenol A in Chronic Kidney Disease [PDF]
International Journal of Nephrology, 2013 Phenols are uremic toxins of intestinal origin formed by bacteria during protein metabolism. Of these molecules, p-cresol is the most studied and has been associated with renal function impairment and vascular damage. Bisphenol A (BPA) is a molecule with structural similarity with phenols found in plastic food and beverage containers as well as in some
González Parra, Emilio José +5 more
openaire +4 more sources
The Podocyte in Diabetic Kidney Disease
The Scientific World Journal, 2009 Approaching epidemic levels, diabetic kidney disease (DKD) is now the leading cause of end-stage renal disease (ESRD). Microalbuminuria is an early clinical marker of DKD that results from damage to the glomerular filtration barrier at the level of the ...
Erin Stitt-Cavanagh +2 more
doaj +1 more source