Results 31 to 40 of about 7,300,383 (289)

Antiplatelet therapy for the prevention of atherosclerosis in chronic kidney disease (ALTAS-CKD) patients: study protocol for a randomized clinical trial

Trials, 2021
Background Cardiovascular disease (CVD) is the most common complication and the leading cause of death in patients with chronic kidney disease (CKD).
Jiachuan Xiong, Ting He, Zhikai Yu, Ke Yang, Feng Chen, Jingbo Cheng, Yu Shi, Yinghui Huang, Yu Qiao, Haiyang Li, Yunzhu Shen, Jinghong Zhao   +11 more
doaj   +1 more source

Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]

, 2005
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders, Ninichuk, Volha, Anders, Hans-Joachim, Volha Ninichuk   +3 more
core   +1 more source

Impact of hemodialysis solutions containing different levels of molecular hydrogen (H2) on the patient-reported outcome of fatigue

Renal Replacement Therapy, 2022
Background Reportedly, dialysis solutions containing molecular hydrogen (H2) might ameliorate patient-reported fatigue in hemodialysis (HD) patients. However, it is unknown whether its impact might differ with different H2 levels. Method This single-arm,
Susumu Uemura, Yoshitaka Kegasa, Keigo Tada, Taichi Tsukahara, Shigeru Kabayama, Tae Yamamoto, Mariko Miyazaki, Joji Takada, Masaaki Nakayama   +8 more
doaj   +1 more source

Hepatitis B and C co-Infection are independent predictors of progressive kidney disease in HIV-positive, antiretroviral-treated adults [PDF]

, 2012
Chronic kidney disease (CKD) is an important cause of morbidity and mortality in HIV-positive individuals. Hepatitis C (HCV) co-infection has been associated with increased risk of CKD, but prior studies lack information on potential mechanisms.
Bickel, M, ESPRIT Study Group, Amanda Mocroft, Christina M Wyatt, Ross, Michael J., Aleksandra Szymczak, ESPRIT Study Group, Daniel Grint, Jens Lundgren, Ryom, Lene, Lene Ryom, Neuhaus, Jacqueline, Bickel, Markus, Szymczak, A, Peters, L, Jacqueline Neuhaus, Ross, MJ, Michael J Ross, Koirala, J, Neuhaus, J, Szymczak, Aleksandra, Mocroft, Amanda, Peters, Lars, Grint, D, Markus Bickel, Grint, Daniel, Wyatt, CM, Janak Koirala, INSIGHT SMART Study Group, Lundgren, Jens, Ross, Michael J, Koirala, Janak, Ryom, L, Mocroft, A, Lars Peters, Lundgren, J, Wyatt, Christina M, Wyatt, Christina M.   +37 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

韩国2型糖尿病患者谷氨酸升高与纤溶酶原水平升高有关

Journal of Diabetes, 2023
Background Glutamate is a major neurotransmitter, although it causes cytotoxicity and inflammation in nonneuronal organs. This study aimed to investigate the metabolic disorders in which glutamate, associated with type 2 diabetes onset, is induced in the
Hyo Jung Lee, Jeong Won Yeom, Ji Ho Yun, Han Byul Jang, Min‐Gyu Yoo, Hyo‐Jin Kim, Soo Kyung Koo, Hye‐Ja Lee   +7 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

BMC Molecular and Cell Biology, 2020
Background Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to
Yan Li, Yong Liu, Kailong Wang, Yinghui Huang, Wenhao Han, Jiachuan Xiong, Ke Yang, Mingying Liu, Tangli Xiao, Chi Liu, Ting He, Xianjin Bi, Jingbo Zhang, Bo Zhang, Jinghong Zhao   +14 more
doaj   +1 more source

Relationship between lysosomal dyshomeostasis and progression of diabetic kidney disease

Cell Death and Disease, 2021
Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular material circulation. They play a key role in the maintenance of cellular physiological homeostasis.
Man Wu, Minjie Zhang, Yaozhi Zhang, Zixian Li, Xingyu Li, Zejian Liu, Huafeng Liu, Xiaoyu Li   +7 more
doaj   +1 more source