Results 31 to 40 of about 6,876,919 (290)

The prevalence and identification of chronic kidney disease in Switzerland [PDF]

, 2015
BACKGROUND: Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. Patients in early CKD stages are often asymptomatic or show non-specific symptoms.
Tomonaga, Yuki
core   +1 more source

The effect of the association between CETP variant type and alcohol consumption on cholesterol level differs according to the ALDH2 variant type

Scientific Reports, 2022
Alcohol consumption is associated with a high increased lipid profile and this association may depend on genetic risk factors. In this study, we aimed to assess the effects of genetic variation associated with alcohol consumption on lipid profiles using ...
Min-Gyu Yoo, Ji Ho Yun, Soo Kyung Koo, Hye-Ja Lee   +3 more
doaj   +1 more source

AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model

European Journal of Medical Research, 2022
Hyperuricemia can induce acute and chronic kidney damage, but the pathological mechanism remains unclear. The potential role of AMP-activated protein kinase (AMPK) α2 in hyperuricemia-induced renal injury was investigated in this study. Acute and chronic
Chen Yang, Hong-yong Su, Ning An, Hong-luan Wu, Xiao-yan Guo, Zhi-hang Li, Xiao-cui Chen, Shao-ping Zhu, Dan Wu, Hui-yuan Li, Qing-jun Pan, Dong Liang, Hua-feng Liu   +12 more
doaj   +1 more source

The cost of implementing UK guidelines for the management of chronic kidney disease [PDF]

, 2007
Background. Chronic kidney disease (CKD) is a major public health problem. In the UK, guidelines have been developed to facilitate case identification and management.
B. Klebe, Stevens, PE, H. Hobbs, Lamb, EJ, Cooley, R, Hobbs, Helen, Irving, J, John, Ian, Hobbs, H, D. J. O'Donoghue, Farmer, CKT, J. New, Klebe, Bernhard, Middleton, R, S. de Lusignan, Klebe, B, Middleton, Rachel, J. Irving, O'Donoghue, DJ, John, I, R. Middleton, I. John, Stevens, Paul E., P. E. Stevens, New, John, Cooley, Roger, Lamb, Edmund J., R. Cooley, O'Donoghue, Donal J., Farmer, Chris, de Lusignan, S, New, J, Irving, Jean, de Lusignan, Simon, C. K.T. Farmer, E. J. Lamb   +35 more
core   +2 more sources

Blockage of the lysosome-dependent autophagic pathway contributes to complement membrane attack complex-induced podocyte injury in idiopathic membranous nephropathy

Scientific Reports, 2017
Dysregulation of autophagy-mediated podocyte homeostasis is proposed to play a role in idiopathic membranous nephropathy (IMN). In the present study, autophagic activity and lysosomal alterations were investigated in podocytes of IMN patients and in ...
Wei Jing Liu, Zhi-hang Li, Xiao-cui Chen, Xiao-lu Zhao, Zhen Zhong, Chen Yang, Hong-luan Wu, Ning An, Wei-yan Li, Hua-feng Liu   +9 more
doaj   +1 more source

Hydroxychloroquine administration exacerbates acute kidney injury complicated by lupus nephritis

Arthritis Research & Therapy, 2022
Background Hydroxychloroquine (HCQ) has been recommended as a basic treatment for lupus nephritis (LN) during this decade based on its ability to improve LN-related renal immune-mediated inflammatory lesions.
Ning An, Chen Yang, Hong-Luan Wu, Yun Guo, Xi-Jie Huang, Tong-Sheng Huang, Zhi-Hong Wu, Jing Xue, Rui-Hong Chen, Zhi-Hang Li, Qing-Jun Pan, Hua-Feng Liu   +11 more
doaj   +1 more source

Kidney disease management in UK primary care: guidelines, incentives and Information Technology [PDF]

, 2007
The last few years have seen new developments to understand and tackle the significant public health issue posed by chronic kidney disease (CKD). Established renal disease currently consumes 2% of the UK National Health Service budget and predictions are
O'Donoghue, Donal J., Middleton, Rachel, Newport, John, Farmer, Chris, de Lusignan, Simon, Klebe, Bernhard, Stevens, Paul E., Cooley, Roger   +7 more
core   +1 more source

Serum klotho level as an indicator for predicting the progression of renal function in chronic kidney disease stages 3~5

Di-san junyi daxue xuebao, 2020
Objective To investigate the association of serum klotho level with renal function deterioration and whether serum klotho level can be used as a predictor of progression of chronic kidney disease (CKD) into renal end point events.
YANG Jiangxin, XIONG Jiachuan, YANG Ke, ZHAO Jinghong   +3 more
doaj   +1 more source

ACE2 deficiency exacerbates obesity-related glomerulopathy through its role in regulating lipid metabolism

Cell Death Discovery, 2022
Obesity-related glomerulopathy is a secondary glomerular disease and its incidence has been increased globally in parallel with the obesity epidemic. ORG emerged as a growing cause of end-stage renal disease in recent years.
Yin-Yin Chen, Han Hong, Yu-Ting Lei, Jia Zou, Yi-Ya Yang, Li-Yu He   +5 more
doaj   +1 more source

Bone Disease in Chronic Kidney Disease and Kidney Transplant

Nutrients, 2022
Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) comprises alterations in calcium, phosphorus, parathyroid hormone (PTH), Vitamin D, and fibroblast growth factor-23 (FGF-23) metabolism, abnormalities in bone turnover, mineralization, volume, linear growth or strength, and vascular calcification leading to an increase in bone fractures and ...
Bellorin-Font, Ezequiel, Rojas, Eudocia, Martin, Kevin J.   +2 more
openaire   +2 more sources