Results 21 to 30 of about 1,268,979 (296)

Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]

, 2018
Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean, Halliday, Christopher, Jahagirdar, Ravi, Johansson, Jan O, Kalantar-Zadeh, Kamyar, Kulikowski, Ewelina, Robson, Richard, Stotz, Stephanie C, Sweeney, Michael, Tsujikawa, Laura M, Wasiak, Sylwia, Wong, Norman C   +11 more
core   +2 more sources

Phenotype standardization for drug-induced kidney disease. [PDF]

, 2015
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda, Cerda, Jorge, Chakaravarthi, Raj, Davenport, Andrew, Goldstein, Stuart L, Holden, Arthur L, Macedo, Etienne, Mehta, Ravindra L, Murray, Patrick T   +8 more
core   +2 more sources

Chronic Kidney Disease Progression [PDF]

Journal of the American Society of Nephrology, 2006
Whether we like it or not, nephrologists around the world have been called to action. Our mission is to attenuate the growth of chronic kidney disease (CKD). Several conditions will need to gel for us to succeed.
Allison A, Eddy, Eric G, Neilson
openaire   +2 more sources

The Podocyte in Diabetic Kidney Disease

The Scientific World Journal, 2009
Approaching epidemic levels, diabetic kidney disease (DKD) is now the leading cause of end-stage renal disease (ESRD). Microalbuminuria is an early clinical marker of DKD that results from damage to the glomerular filtration barrier at the level of the ...
Erin Stitt-Cavanagh, Laura MacLoed, Chris R.J. Kennedy   +2 more
doaj   +1 more source

The effect of the association between CETP variant type and alcohol consumption on cholesterol level differs according to the ALDH2 variant type

Scientific Reports, 2022
Alcohol consumption is associated with a high increased lipid profile and this association may depend on genetic risk factors. In this study, we aimed to assess the effects of genetic variation associated with alcohol consumption on lipid profiles using ...
Min-Gyu Yoo, Ji Ho Yun, Soo Kyung Koo, Hye-Ja Lee   +3 more
doaj   +1 more source

Gout and risk of chronic kidney disease and nephrolithiasis meta-analysis of observational studies [PDF]

, 2015
ntroduction To determine the prevalence of chronic kidney disease and nephrolithiasis in people with gout, and the association between gout and prevalent or incident chronic kidney disease and nephrolithiasis.
Belcher, J, Mallen, CD, Roddy, E
core   +2 more sources

AMP-activated protein kinase α2 contributes to acute and chronic hyperuricemic nephropathy via renal urate deposition in a mouse model

European Journal of Medical Research, 2022
Hyperuricemia can induce acute and chronic kidney damage, but the pathological mechanism remains unclear. The potential role of AMP-activated protein kinase (AMPK) α2 in hyperuricemia-induced renal injury was investigated in this study. Acute and chronic
Chen Yang, Hong-yong Su, Ning An, Hong-luan Wu, Xiao-yan Guo, Zhi-hang Li, Xiao-cui Chen, Shao-ping Zhu, Dan Wu, Hui-yuan Li, Qing-jun Pan, Dong Liang, Hua-feng Liu   +12 more
doaj   +1 more source

Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup [PDF]

, 2017
Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice.
A Dewitte, A Ishani, A Ishani, A Morden, AB Pai, AG Schneider, AJ Lewington, Alexander Zarbock, AM Patel, AS Levey, Azra Bihorac, B Rodriguez-Iturbe, B Rodriguez-Iturbe, BB Newsome, BJ Philips, BS Moffett, C Mudumbai, C Ronco, C Vinsonneau, C-T Chao, CC Shiao, CJ Kirwan, Claudio Ronco, CM Bell, CM Horkan, CY Hsu, CY Hsu, D Korenkevych, D Ponce, D Schnell, David Bittleman, Dinna Cruz, DM Thomas, DW Brown, E Wang, EA Coleman, EA Hoste, EA Hoste, EA Hoste, ED Siew, ED Siew, ED Siew, ED Siew, ED Siew, Edward D. Siew, Eric Hoste, ES Kirkendall, Etienne Macedo, F Lapi, FG Brivet, GV do Nascimento, H de Geus, H Graf, H Schiffl, HL Smets, I Benz-de Bretagne, I Koulouridis, I Nachtigall, ID Bucaloiu, IH Khan, J Bouchard, J Bouchard, J Herrera, J Herrera, J Kaufman, J Zavada, JA Kellum, JA Kellum, JA Kellum, JA Kellum, Jay Koyner, JF Platt, JJ Dixon, JO Friedrich, John A. Kellum, JP Bosch, JP Nicholson, JR Brown, JR Brown, JR Prowle, JW Pickering, JW Pickering, K Doi, K Solez, Kathleen D. Liu, KD Liu, KR Pechman, L Cox, LA Tomlinson, Lakhmir S. Chawla, LJ Hickson, LS Chawla, LS Chawla, LS Chawla, LS Chawla, LS Chawla, Lui Forni, M Carlier, M Darmon, M Heung, M Heung, M Huber, M James, M Jun, M Monseu, M Xie, MA Onuigbo, Marlies Ostermann, MB Kwong, ME Matheny, Mitchell Rosner, Mitra Nadim, MM Chrymko, MM Sood, MT James, MT James, N Pannu, N Srisawat, Neesh Pannu, P Sharma, PA Duran, Patrick Murray, Paul M. Palevsky, PH van der Voort, PK Tao Li, PM Palevsky, PM Palevsky, R Cartin-Ceba, R Chu, R Jelliffe, R Rivosecchi, R Wald, R Wald, RA Parker, Ravindra Mehta, Rinaldo Bellomo, RK Basu, RL Amdur, RL Mehta, Robert L. Fitzgerald, Ron Wald, S Chen, S Ftouh, S Ninet, S Perinel, S Uchino, S Uchino, SA Silver, Sandra L. Kane-Gill, SC Gautam, Sean M. Bagshaw, SG Coca, SG Coca, SL Goldstein, SL Goldstein, SL Hu, SL Kane-Gill, SM Bagshaw, SM Handler, SM Jang, SM Lee, SM Moran, SP Kelleher, Stuart L. Goldstein, TJ Pianta, TY Wu, VC Wu, VC Wu, W Picard, Z Harel, ZH Endre, ZH Endre, ZL Cox, Zoltan Endre   +173 more
core   +2 more sources

Serum klotho level as an indicator for predicting the progression of renal function in chronic kidney disease stages 3~5

Di-san junyi daxue xuebao, 2020
Objective To investigate the association of serum klotho level with renal function deterioration and whether serum klotho level can be used as a predictor of progression of chronic kidney disease (CKD) into renal end point events.
YANG Jiangxin, XIONG Jiachuan, YANG Ke, ZHAO Jinghong   +3 more
doaj   +1 more source

Fluctuations of estimated glomerular filtration rate outside kidney disease improving global outcomes diagnostic criteria for acute kidney injury in end-stage liver disease outpatients and outcome postliver transplantation [PDF]

, 2017
Background. Renal dysfunction in end-stage liver disease (ESLD) results fromsystemic conditions that affect both liver and kidney with activation of vasoconstrictor systems.
Berloco, Pasquale Bartolomeo, Cappoli, Andrea, Fiacco, Federica, GINANNI CORRADINI, Stefano, Melandro, Fabio, Merli, Manuela, Mitterhofer, Anna Paola, Nofroni, Italo, Poli, Edoardo, Rossi, Massimo, Tinti, Francesca, Umbro, Ilaria, Zavatto, Assunta   +12 more
core   +1 more source