Thiazides in advanced chronic kidney disease—time for a randomized controlled trial? [PDF]
, 2015 Purpose of review: Chronic kidney disease is common, associated with increased cardiovascular risk, and frequently complicated by hypertension, requiring multiple agents for control.
Agarwal, Rajiv, Sinha, Arjun D.
core +1 more source
Relationship between lysosomal dyshomeostasis and progression of diabetic kidney disease
Cell Death and Disease, 2021 Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular material circulation. They play a key role in the maintenance of cellular physiological homeostasis.
Man Wu +7 more
doaj +1 more source
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells
BMC Molecular and Cell Biology, 2020 Background Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to
Yan Li +14 more
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Erratum: Evans M, Grams ME, Sang Y, et al., for the Chronic Kidney Disease Prognosis Consortium. Risk factors for prognosis in patients with severely decreased GFR. Kidney Int Rep. 2018;3:625-637. [PDF]
, 2018 [This corrects the article DOI: 10.1016/j.ekir.2018.01.002.]
Chronic Kidney Disease Prognosis Consortium
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Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Paediatric chronic kidney disease
South African Medical Journal, 2015 Doctors use various guidelines on paediatric chronic kidney disease (CKD) for managing their patients according to the availability of resources. As with adolescent and adult patients, CKD in children can also progress to end-stage renal failure - the time course being influenced by several modifiable factors.
Van Biljon, I., Meyers, A.M.
openaire +6 more sources
Patient Activation with Knowledge, Self-Management, and Confidence in Chronic Kidney Disease [PDF]
, 2015 Background Chronic kidney disease is a growing health problem on a global scale. The increasing prevalence of chronic kidney disease presents an urgent need to better understand the knowledge, confidence and engagement in self-managing the disease ...
Hertzog, Melody +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
Is “chronic kidney disease” a disease? [PDF]
Journal of Evaluation in Clinical Practice, 2018 AbstractSeveral philosophers of medicine have attempted to answer the question “what is disease?” In current clinical practice, an umbrella term “chronic kidney disease” (CKD) encompasses a wide range of kidney health states from commonly prevalent subclinical, asymptomatic disease to rare end‐stage renal disease requiring transplant or dialysis to ...
Smart, B, Stevens, R, Verbakel, J
openaire +3 more sources
Alleles of CYP3A5 and their association with renal function in chronic kidney disease [PDF]
PeerJBackground The cytochrome P450 family 3 subfamily A polypeptide 5 (CYP3A5) gene plays an important role in renal function through its product’s involvement in metabolizing endogenous substances and drugs, including immunosuppressants used following ...
Onnapa Kongphan +7 more
doaj +2 more sources