Results 11 to 20 of about 596,348 (255)

Oroxylin A ameliorates AKI-to-CKD transition through maintaining PPARα-BNIP3 signaling-mediated mitochondrial homeostasis

open access: yesFrontiers in Pharmacology, 2022
Background: Acute kidney injury (AKI) occurs in approximately 7–18% of all hospitalizations, but there are currently no effective drug therapy for preventing AKI or delaying its progression to chronic kidney disease (CKD).
Mengying Yao   +12 more
doaj   +1 more source

A Novel Mutation of UMOD in a Chinese Family with IgA Nephropathy: A Case Report

open access: yesCase Reports in Nephrology and Dialysis, 2023
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with varying clinical presentations. The hereditary susceptibility to IgAN is rather complex. In this report, a Chinese case of IgAN was recruited. Renal biopsy showed the
Furong Li   +5 more
doaj   +1 more source

Visit-to-visit ultrafiltration volume variability predicts all-cause mortality in patients receiving hemodialysis

open access: yesRenal Failure, 2023
Purpose Little is known about the effect of visit-to-visit ultrafiltration volume (UV) variability on the outcome. In this study, we investigated the association between visit-to-visit UV variability and all-cause mortality in patients receiving ...
Quanchao Zhang   +9 more
doaj   +1 more source

Klotho protects against chronic kidney disease-associated atherosclerotic plaque vulnerability in

open access: yesDi-san junyi daxue xuebao, 2020
Objective To explore the effects of chronic kidney disease (CKD) on the instability of atherosclerotic plaques and investigate the role of Klotho in this pathological process.
BI Xianjin   +4 more
doaj   +1 more source

Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration

open access: yesNature Communications, 2023
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the mechanisms underlying this intricate molecular crosstalk remain elusive.
Chi Liu   +13 more
doaj   +1 more source

Chronic Kidney Disease [PDF]

open access: yesAnnals of Internal Medicine, 2009
This issue provides a clinical overview of chronic kidney disease, focusing on prevention, diagnosis, treatment, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment ...
Paul, Drawz, Mahboob, Rahman
openaire   +2 more sources

The molecular mechanisms and intervention strategies of mitophagy in cardiorenal syndrome

open access: yesFrontiers in Physiology, 2022
Cardiorenal syndrome (CRS) is defined as a disorder of the heart and kidney, in which acute or chronic injury of one organ may lead to acute or chronic dysfunction of the other.
Mengying Yao   +8 more
doaj   +1 more source

Association between the Triglyceride Glucose Index and All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury

open access: yesKidney Diseases, 2023
Introduction: The triglyceride glucose (TyG) index is a reliable alternative biomarker of insulin resistance, but the association between the TyG index and acute kidney injury (AKI) in critically ill patients remains unclear.
Liangjing Lv   +4 more
doaj   +1 more source

Up-regulation of GCLM alleviates ferroptosis in renal tubular epithelial cells induced by hypoxia reoxygenation injury

open access: yes陆军军医大学学报, 2023
Objective To explore the role and mechanism of glutamate-cysteine ligase modifier subunit (GCLM) in alleviation of hypoxia reoxygenation (HR) injury in renal tubular epithelial cells.
GONG Shuiqin   +2 more
doaj   +1 more source

Adiponectin in Chronic Kidney Disease [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is present in the kidneys, mainly in the arterial endothelium and smooth muscle cells, as well as in the capillary endothelium, and might be considered as a marker of many negative ...
Jarosław Przybyciński   +4 more
openaire   +2 more sources

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