Results 11 to 20 of about 596,348 (255)
Background: Acute kidney injury (AKI) occurs in approximately 7–18% of all hospitalizations, but there are currently no effective drug therapy for preventing AKI or delaying its progression to chronic kidney disease (CKD).
Mengying Yao +12 more
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A Novel Mutation of UMOD in a Chinese Family with IgA Nephropathy: A Case Report
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with varying clinical presentations. The hereditary susceptibility to IgAN is rather complex. In this report, a Chinese case of IgAN was recruited. Renal biopsy showed the
Furong Li +5 more
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Purpose Little is known about the effect of visit-to-visit ultrafiltration volume (UV) variability on the outcome. In this study, we investigated the association between visit-to-visit UV variability and all-cause mortality in patients receiving ...
Quanchao Zhang +9 more
doaj +1 more source
Klotho protects against chronic kidney disease-associated atherosclerotic plaque vulnerability in
Objective To explore the effects of chronic kidney disease (CKD) on the instability of atherosclerotic plaques and investigate the role of Klotho in this pathological process.
BI Xianjin +4 more
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Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration
Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the mechanisms underlying this intricate molecular crosstalk remain elusive.
Chi Liu +13 more
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This issue provides a clinical overview of chronic kidney disease, focusing on prevention, diagnosis, treatment, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment ...
Paul, Drawz, Mahboob, Rahman
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The molecular mechanisms and intervention strategies of mitophagy in cardiorenal syndrome
Cardiorenal syndrome (CRS) is defined as a disorder of the heart and kidney, in which acute or chronic injury of one organ may lead to acute or chronic dysfunction of the other.
Mengying Yao +8 more
doaj +1 more source
Introduction: The triglyceride glucose (TyG) index is a reliable alternative biomarker of insulin resistance, but the association between the TyG index and acute kidney injury (AKI) in critically ill patients remains unclear.
Liangjing Lv +4 more
doaj +1 more source
Objective To explore the role and mechanism of glutamate-cysteine ligase modifier subunit (GCLM) in alleviation of hypoxia reoxygenation (HR) injury in renal tubular epithelial cells.
GONG Shuiqin +2 more
doaj +1 more source
Adiponectin in Chronic Kidney Disease [PDF]
Adiponectin is the adipokine associated with insulin sensitization, reducing liver gluconeogenesis, and increasing fatty acid oxidation and glucose uptake. Adiponectin is present in the kidneys, mainly in the arterial endothelium and smooth muscle cells, as well as in the capillary endothelium, and might be considered as a marker of many negative ...
Jarosław Przybyciński +4 more
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