Results 31 to 40 of about 465,591 (312)

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease

, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer, Christian Fork (70601), Brandes, Ralf P., Brandes, Ralf, Schäfer, Liliana, Pavenstädt, Hermann, Kerstin Amann, Felix Jansen, Kerstin Sander (481042), Jung, Oliver, Ralf P Brandes, Holger Stark, Hermann Pavenstädt, Löhn, Matthias, Oliver Plettenburg (481045), Plettenburg, Oliver, Hartmut Ruetten (481044), Felix Jansen (362745), Holger Stark (4694), Christoph Daniel (282746), Liliana Schäfer (481043), Kerstin Amann (186160), Oliver Jung (362744), Ralf P. Brandes (362753), Kerstin Sander, Oliver Jung, Fork, Christian, Babelova, Andrea, Matthias Löhn, Hermann Pavenstädt (108698), Sander, Kerstin, Ruetten, Hartmut, Oliver Plettenburg, Hartmut Ruetten, Jansen, Felix, Andrea Babelova, Christian Fork, Stark, Holger, Christoph Daniel, Matthias Löhn (171195), Andrea Babelova (362749), Daniel, Christoph, Amann, Kerstin   +42 more
core   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Frequency-reduction strategy of roxadustat in patients undergoing peritoneal dialysis: a multi-center retrospective cohort study

Frontiers in Medicine
BackgroundAlthough dose reduction is the guideline-recommended tapering strategy for roxadustat to maintain target hemoglobin levels in peritoneal dialysis (PD) patients during the maintenance phase, reducing the administration frequency represents ...
Xi Mi, Xi Mi, Xi Mi, Xi Mi, Xi Mi, Guanying Lin, Guanying Lin, Guanying Lin, Guanying Lin, Guanying Lin, Yijing Fang, Yijing Fang, Yijing Fang, Yijing Fang, Yijing Fang, Lu Zhu, Yanhong Lin, Yanhong Lin, Yanhong Lin, Yanhong Lin, Yanhong Lin, Tingting Zhang, Tingting Zhang, Tingting Zhang, Tingting Zhang, Tingting Zhang, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaoyan Su, Xiaoyan Su, Xianrui Dou, Jun Ai, Jun Ai, Jun Ai, Jun Ai, Jun Ai   +38 more
doaj   +1 more source

Management of hyperkalaemia in acute kidney injury in a heart failure patient with patiromer

ESC Heart Failure, 2020
Aims One prevalent comorbidity of chronic heart failure (CHF) is chronic kidney disease(CKD). Hyperkalemia is associated with both CHF and CKD, which often leads to withdrawal of heart failure medications in clinical praxis. Methods and results A patient
Jonathan Slawik, Juliane Dederer, Ingrid Kindermann, Michael Böhm   +3 more
doaj   +1 more source

APOL1 Genotype, Proteinuria, and the Risk of Kidney Failure: A Secondary Analysis of the AASK (African American Study of Kidney Disease and Hypertension) and CRIC (Chronic Renal Insufficiency Cohort) StudiesPlain-Language Summary

Kidney Medicine, 2022
Rationale & Objective: Patients with a high-risk Apolipoprotein L1 (APOL1) genotype are more likely to develop chronic kidney disease and kidney failure. It is unclear whether this increased risk is entirely mediated by the development of proteinuria.
Anthony Nguyen, Sze-chuan Suen, Eugene Lin   +2 more
doaj   +1 more source

Chronic Kidney Disease – Where Next? : Predicting Outcomes And Planning Care Pathways [PDF]

, 2014
Peer ...
Marks, Angharad, Black, Corri, Fluck, Nicholas, Angharad Marks, Nicholas Fluck, Corri Black   +5 more
core  

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Respiratory failure: A rare complication of chronic kidney disease mineral and bone disorder

, 2019
Background: Disordered metabolism of bone and minerals is a problem frequently encountered in patients with chronic kidney disease. Early biochemical changes include altered calcium and phosphate balance, while advanced disease produces reduced bone ...
Yaxley, J, Scott, T
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

A new outlook towards kidney injuries

, 2012
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Mahesh Satwekar, Abhijeet Satwekar
core   +1 more source