Results 111 to 120 of about 690,557 (312)

Acute-on-chronic liver failure: a review

, 2014
Luis Eduardo Zamora Nava,1 Jonathan Aguirre Valadez,2 Norberto C Chávez-Tapia,3 Aldo Torre21Department of Endoscopy, 2Department of Gastroenterology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, 3Obesity and ...
Zamora Nava LE, Torre A, Aguirre Valadez J, Chávez-Tapia NC   +3 more
core  

Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma

, 2011
Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies ...
Polta, Andreas, Kronenberger, Bernd, Peveling-Oberhag, Jan, Bernd Kronenberger, Haupenthal Jörg, Susser, Simone, Andreas Polta, Susser Simone, Welker, Martin, Piiper, Albrecht, Trojan Jörg, Jörg Trojan, Forestier, Nicole, Radeke, Heinfried H., Peveling-Oberhag Jan, Heinfried H Radeke, Verena Bihrer, Jan Peveling-Oberhag, Heinfried H. Radeke, Welker, Martin-Walter, Polta Andreas, Radeke Heinfried H., Nicole Forestier, von Wagner Michael, Kronenberger Bernd, Stefan Zeuzem, Friedrich-Rust Mireen, Oliver Waidmann, Friedrich-Rust, Mireen, Michael von Wagner, Sarrazin, Christoph, Radeke, Heinfried H, Zeuzem Stefan, Christoph Sarrazin, Martin Welker, Shi Ying, Jörg Haupenthal, von Wagner, Michael, Simone Susser, Forestier Nicole, Piiper Albrecht, Bihrer Verena, Bihrer, Verena, Haupenthal, Jörg, Welker Martin, Sarrazin Christoph, Shi, Ying, Peveling-Oberhag, Jan Franz-Josef, Mireen Friedrich-Rust, Waidmann Oliver, Waidmann, Oliver, Albrecht Piiper, Trojan, Jörg, Ying Shi, Wagner, Michael von, Zeuzem, Stefan   +55 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Proposal of a new diagnostic algorithm for hepatocellular carcinoma based on the Japanese guidelines but adapted to the Western world for patients under surveillance for chronic liver disease

, 2016
To date, despite many scientific evidences, the guidelines of the principal hepatological societies, such as the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association ...
Bologna Liver Oncology Group (BLOG), Renzulli, Matteo, Golfieri, Rita   +2 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

PATHOPHYSIOLOGY, CLINICAL FEATURES, AND MANAGEMENT OF CHILDREN WITH CHRONIC INFECTIOUS DISEASES

, 2009
Children with chronic diseases Chronic viral hepatitis Among human hepatitis viruses, hepatitis B (HBV) and C (HCV) viruses are able to persist in the host for years and thereby causing chronic hepatitis.
Giannattasio, Antonietta
core  

Love in the Time of Corona [PDF]

Hospital Practices and Research, 2020
Seyed Mohammadreza Hashemian, Amir Vahedian Azimi, Mohamad Amin Pourhoseingholi   +2 more
doaj   +1 more source

Microbial Translocation in Chronic Liver Diseases

International Journal of Microbiology, 2012
The intestinal microflora is not only involved in the digestion of nutrients, but also in local immunity, forming a barrier against pathogenic microorganisms.
Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, Giuseppe Nunnari   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Secondary Hepatosiderosis in Chronic Liver Diseases Based on the Results of Morphological Examination of Hepatobiopsy Specimens

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to identify the frequency of secondary hepatosiderosis not related to hereditary hemochromatosis, depending on the etiology of chronic diffuse liver disease, in a retrospective study based on the results of morphological examination of liver ...
V. V. Stelmakh, V. K. Kozlov, I. A. Samusenko   +2 more
doaj   +1 more source