Results 101 to 110 of about 1,722,968 (253)

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

The APLC expert consensus recommendations on the management of chronic lymphocytic leukaemia in Asia

Annals, Academy of Medicine, Singapore
Introduction: Targeted therapies have significantly transformed the management of chronic lymphocytic leukaemia (CLL), yet most recommendations continue to reflect Western practice patterns.
Shin Yeu Ong, Thomas Chan, Eric Wai Choi Tse, Stephen Mulligan, Ping Chong Bee, Koji Izutsu, Jin Seok Kim, Bor Sheng Ko, Jianyong Li, Soo Chin Ng, Lalita Norasetthada, Lugui Qiu, Thanawat Rattanathammethee, Constantine Tam, Shuhua Yi, Huayuan Zhu, Yeow Tee Goh   +16 more
doaj   +1 more source

Chronic Lymphocytic Leukaemia

, 2009
Chronic lymphocytic leukaemia remains the most common adult leukaemia in Western countries. In this review we tried to give an overview of the important prognostic markers and the developments in this field.
Lust, SofieUZGent001997411367801001805974976801969901F6F2FC5C-F0ED-11E1-A9DE-61C894A0A6B4, Boelens, Jerina, Offner, Fritz, Lust, Sofie, Vanhoecke, Barbara, Boelens, JerinaGE32UZGent0019962313048010017667700000-0003-2282-819400EBF70E-F0EE-11E1-A9DE-61C894A0A6B4, Vanhoecke, BarbaraUGent001992330486801001624102976635044217F66B2D68-F0ED-11E1-A9DE-61C894A0A6B4, Offner, FritzGE35UZGent0019605016558010005976190000-0003-4690-3603F42CD592-F0ED-11E1-A9DE-61C894A0A6B4   +7 more
core  

Coexistence of immunophenotypically normal and aberrant mast cells in patients with clonal mast cell diseases associates with more indolent subtypes and less severe disease characteristics

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky, Kees Meijer, Marije Nijk, Saskia K. Klein, Hanneke N. G. Oude Elberink, Ido P. Kema, André B. Mulder   +6 more
wiley   +1 more source

Chronic lymphocytic leukaemia genetics overview

, 2007
Although the familial aspect of chronic lymphocytic leukaemia (CLL) has been appreciated for decades, it is only with the recent confluence of improved molecular and gene technologies and world-wide collaborative networks that accelerated progress has ...
Christoph Plass, Raveche, E, Plass, C, Mcmaster, Mary Lou, Caporaso, N, Raveche, Elizabeth, George Calin, Goldin, L, Caporaso, Neil, Ola Landgren, Calin, G, Marti, G, NG, David, Slager, Susan, McMaster, ML, Neil Caporaso, Susan Slager, Landgren, O,, Plass, Christoph, Marti, Gerald, Calin, George, Landgren, Ola, Bauer, S, Mary Lou McMaster, Gerald Marti, Ng, D, Bauer, Steven, Goldin, Lynn, Steven Bauer, Elizabeth Raveche, David Ng, Lynn Goldin, Landgren, Carl   +32 more
core   +1 more source

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

Two rare diagnoses during chronic lymphocytic leukaemia follow-up: Kaposi’s sarcoma and Merkel cell carcinoma

, 2016
Chronic lymphocytic leukaemia often has a clinical presentation characterised by increased neoplastic lymphocytes which are mostly mature looking due to B lymphocytes.
Keskin, Ali, Hacıoğlu, Sibel, Dogu, M.H., Hacioglu, Sibel, SARI, İSMAİL, Sarı, Hakan İsmail, Degirmencioğlu, Serkan, Şen, Nilay, Dogu, Mehmet H.   +8 more
core   +1 more source

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings, Orrin Koepke, Jason E. Love, Alireza Torabi, Lianqun Qiu, Jonathan R. Fromm, Sindhu Cherian, Afshin Shameli   +7 more
wiley   +1 more source

Immune failure, infection and survival in chronic lymphocytic leukemia

Haematologica, 2018
Kyle R. Crassini, O. Giles Best, Stephen P. Mulligan   +2 more
doaj   +1 more source