Results 181 to 190 of about 46,203 (306)

Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1. [PDF]

Nat Commun
Cocomazzi PG, Iatrou A, Minici C, Gounari M, Linder AT, Akpınaroğlu C, Patrone M, Broggini L, Frenquelli M, Sarrigeorgiou I, Lymberi P, Petrakis G, Koletsa T, Scarfò L, Agathangelidis A, Jumaa H, Maity PC, Ghia P, Stamatopoulos K, Degano M.   +19 more
europepmc   +1 more source

Blue‐Gray Papules on the Chest and Face

JEADV Clinical Practice, EarlyView.
Sanjana Likki, Kevin Lee, Priyadharsini Nagarajan, Doina Ivan, Woo Cheal Cho, Fiorinda Muhaj   +5 more
wiley   +1 more source

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

Rare Metals, EarlyView.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang, Jiatong Lin, Yi Peng, Zehua Wu, Yingying Liu, Wei Duan, Qiaolin Wei, Jia‐Wei Shen, Jiang‐Xing Chen, Yong Guo   +9 more
wiley   +1 more source

Re-emergence of circulating non-malignant B cells as a prognostic biomarker in chronic lymphocytic leukaemia. [PDF]

Sci Rep
Lim YJ, Duckworth A, Clarke K, Oates M, Karpha I, Gornall M, Kalakonda N, Slupsky J, Pettitt A.   +8 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Matching-adjusted indirect comparisons of efficacy and safety for zanubrutinib versus the combination of fixed-duration venetoclax and ibrutinib in patients with treatment-naïve chronic lymphocytic leukaemia. [PDF]

Br J Haematol
Munir T, Mohseninejad L, Rakonczai P, Dobi B, Xu S, Yang K, Vezan R, Calle NM.   +7 more
europepmc   +1 more source

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

VIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng, Jiayun Yang, Shouzhi Yang, Ayizekeranmu Yiming, Wenjun Yu, Yuewei Zhao, Chunmeng Ding, Kexin Meng, Si Gao, Yang Li, Nan Dan, Dandan Feng, Yunhua Xu, Lin Huang, Yongxia Qiao   +14 more
wiley   +1 more source

Outcomes of allogeneic haemopoietic transplant for chronic lymphocytic leukaemia in the modern era. [PDF]

Intern Med J
Barge L, Tran S, Kennedy G, Ritchie D, Gottlieb D, Milliken S, Spencer A, Purtill D, Perera T, Doocey R, Larsen S, Butler A, Bardy P, Greenwood M, Durrant S, Curley C, Stewart C, Tam C, Balendran S, Di Ciaccio PR, Patil S, Han MH, Hamad N.   +22 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

CD19 CAR T-Cell Therapy in Richter Transformation: A Multicentre Retrospective Analysis by the European Research Initiative on Chronic Lymphocytic Leukaemia. [PDF]

J Cell Mol Med
Beyar-Katz O, Benjamini O, Delgado J, Ruella M, Ram R, Grisariu S, Visentin A, Vandenberghe E, Gentile M, Avigdor A, Shimoni A, Shouval R, Marcus R, Schuster SJ, Ortiz-Maldonado V, Ghilardi G, Paruzzo L, Zuckerman T, Tadmor T, Fineman R, Amit O, Martinez-Cibrian N, Gabrielli G, Avni B, Minga E, Shem-Tov N, Scarfo L, Yerushalmi R, Nagler A, Leiba R, Danylesko I, Stamatopoulos K, Chatzikonstantinou T, Ghia P, Herishanu Y.   +34 more
europepmc   +1 more source