Albumin activates the AKT signalling pathway and protects B-chronics lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis [PDF]
Anderson, RJ +10 more
core
Outcomes following exposure to drug interactions with ibrutinib in patients with chronic lymphocytic leukaemia. [PDF]
Hoang T +10 more
europepmc +1 more source
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
Adjudication of Adverse Cardiovascular Events in Patients with Chronic Lymphocytic Leukaemia Treated with Ibrutinib: Deaths in GLOW or Blowing in the Wind? [PDF]
Esposito R +4 more
europepmc +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
wiley +1 more source
Should the current diagnostic criteria for CLL be reconsidered? A reply to Johnstone et al. "De-diagnosing chronic lymphocytic leukaemia: An ethical and scientific case for changing diagnostic criteria". [PDF]
Matos DM.
europepmc +1 more source
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche +8 more
wiley +1 more source
An 80-year-old female with multiple mononeuropathy: neuroleukemiosis a rare complication of chronic lymphocytic leukaemia. [PDF]
Morgan C +3 more
europepmc +1 more source

