Results 121 to 130 of about 1,913,070 (304)

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Treating the elderly patient with chronic lymphocytic leukemia: current and emerging options

, 2014
Zahra Mozaheb Department of Hematology-Oncology, Imam-Reza Hospital, Mashhad University of Medical Science, Mashhad, Iran Abstract: Management of cancer in the elderly is an increasingly common problem.
Mozaheb Z
core  

Risk of Developing Subsequent Primary Colorectal Cancers Among Non‐Colorectal Cancer Survivors: Implications for Prevention and Screening

International Journal of Cancer, EarlyView.
ABSTRACT Cancer survivors have an elevated risk of developing subsequent primary cancers, including colorectal cancer (CRC), and may benefit from tailored screening approaches to reduce incidence and morbidity. A retrospective cohort of adults diagnosed with cancer (excluding CRC) in Alberta, Canada from 2000 to 2021 who survived at least 6 months was ...
Dylan E. O'Sullivan, Robert J. Hilsden, Hannah Harsanyi, Matthew T. Warkentin, Kareem Jamani, Huiming Yang, Darren R. Brenner, Safiya Karim, Winson Y. Cheung, Yibing Ruan   +9 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Central nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature

Journal of Medical Case Reports
Background Central nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous system involvement in chronic lymphocytic leukemia. This article aims to analyze the diagnosis and treatment
Li-Yuan Qin, Ye Geng, Jian-Feng Mu, Wen-Jun Wang, Cai-Xia Zhang, Yi-Nan Gao, Jian-Xia He   +6 more
doaj   +1 more source

Interferon Alfa in the treatment of B-cell chronic lymphocytic leukemia [PDF]

, 1994
Knauf, W. U., Maubach, P. A., Adolf, D., Mitrou, P. S., Emmerich, B., Ziegle-Heitbrock, H. W. L., Thiel, E., Langenmayer, Irmgard, Bergmann, L., Dietzfelbinger, H., Nerl, C.   +10 more
core   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Obinutuzumab in chronic lymphocytic leukemia: design, development and place in therapy

, 2017
Othman Al-Sawaf, Kirsten Fischer, Anja Engelke, Natali Pflug, Michael Hallek, Valentin Goede German CLL Study Group, Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany Abstract: For decades, treatment of chronic ...
Hallek M, Engelke A, Al-Sawaf O, Goede V, Fischer K, Pflug N   +5 more
core  

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

CD5-induced apoptosis of B cells in some patients with chronic lymphocytic leukemia

, 2001
Although B chronic lymphocytic leukemia (B-CLL) is characterized by prolonged survival of CD5+ B cells in vivo, these cells apoptose spontaneously in vitro. The effect of CD5 ligation on apoptosis was studied in 27 newly diagnosed patients with B-CLL, in
Berthou, C., Le Calvez, G., Abgrall, J.F., Youinou, P.Y., Burdjanadze, N., Jamin, C., Pers, J.O., Lydyard, P.M., Porakishvili, N.   +8 more
core   +1 more source