Results 11 to 20 of about 73,500 (260)

Determinants of Time-to-Death of Chronic Lymphocytic Leukemia Patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia

Cancer Informatics, 2023
Background: Leukemia is a group of cancers that usually begin in the bone marrow and results in a large number of abnormal white blood cells. Chronic Lymphocytic Leukemia is the most prevalent leukemia in Western countries, with an estimated incidence ...
Gedam Derbew Addisia, Awoke Seyoum Tegegne, Denekew Bitew Belay, Mahider Abere Kassaw, Mitiku Wale Muluneh, Koyachew Bitew Abebe, Bezanesh Melese Masresha, Solomon Sisay Mulugeta, Setegn Muche Fentaw, Dejen Gedamu Damtie   +9 more
doaj   +1 more source

Case report: Identification of atypical mantle cell lymphoma with CCND3 rearrangement by next-generation sequencing

Frontiers in Oncology, 2023
The t(11;14) (q13;q32) translocation resulting in overexpression of cyclin D1 is the major oncogenic mechanism in mantle cell lymphoma (MCL). Most MCLs can be diagnosed based on morphological features, cyclin D1 expression, and IGH/CCND1 rearrangement ...
Luomengjia Dai, Luomengjia Dai, Luomengjia Dai, Han Zhang, Wen Chen, Yi Xia, Yi Xia, Yi Xia, Shuchao Qin, Shuchao Qin, Shuchao Qin, Yang Shao, Jianyong Li, Jianyong Li, Jianyong Li, Yi Miao, Yi Miao, Yi Miao, Bingzong Li, Huayuan Zhu, Huayuan Zhu, Huayuan Zhu   +21 more
doaj   +1 more source

Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification

Frontiers in Microbiology, 2018
Recombinant protein expression has become an invaluable tool in basic and applied research. The accumulated knowledge in this field allowed the expression of thousands of protein targets in a soluble, pure, and homogeneous state, essential for ...
Claudia Ortega, Claudia Ortega, Daniel Prieto, Daniel Prieto, Cecilia Abreu, Cecilia Abreu, Pablo Oppezzo, Pablo Oppezzo, Agustín Correa, Agustín Correa   +9 more
doaj   +1 more source

Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia: New Insights into Leukemic Progression

Molecules, 2017
Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. Due to its catalytic activity, LPL is involved in metabolic pathways exploited by various solid and hematologic malignancies to provide an extra energy source to the tumor cell.
Daniel Prieto, Pablo Oppezzo
doaj   +1 more source

The contribution of CD200 to the diagnostic accuracy of Matutes score in the diagnosis of chronic lymphocytic leukemia in limited resources laboratories.

PLoS ONE, 2021
Flow cytometry immunophenotyping has an essential role in distinguishing chronic lymphocytic leukemia from other B-chronic lymphoproliferative disorders. Recently, CD200 is considered as a relatively consistent marker in chronic lymphocytic leukemia.
Sana Dlawar Jalal
doaj   +1 more source

Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk

Haematologica, 2017
The importance of the tumor microenvironment in chronic lymphocytic leukemia is widely accepted. Nevertheless, the understanding of the complex interplay between the various types of bystander cells and chronic lymphocytic leukemia cells is incomplete ...
Martijn HA van Attekum, Eric Eldering, Arnon P Kater   +2 more
doaj   +1 more source

Elevated risk of chronic lymphocytic leukemia and other indolent non-Hodgkin’s lymphomas among relatives of patients with chronic lymphocytic leukemia

Haematologica, 2009
Background Previous studies have shown increased familial risk for chronic lymphocytic leukemia. In the most comprehensive study to date, we evaluated risk of chronic lymphocytic leukemia and lymphoproliferative disorders among first-degree relatives of ...
Lynn R. Goldin, Magnus Björkholm, Sigurdur Y. Kristinsson, Ingemar Turesson, Ola Landgren   +4 more
doaj   +1 more source

Expression of COBLL1 encoding novel ROR1 binding partner is robust predictor of survival in chronic lymphocytic leukemia

Haematologica, 2018
Chronic lymphocytic leukemia is a disease with up-regulated expression of the transmembrane tyrosine-protein kinase ROR1, a member of the Wnt/planar cell polarity pathway. In this study, we identified COBLL1 as a novel interaction partner of ROR1. COBLL1
Hana Plešingerová, Pavlína Janovská, Archana Mishra, Lucie Smyčková, Lucie Poppová, Antonín Libra, Karla Plevová, Petra Ovesná, Lenka Radová, Michael Doubek, Šárka Pavlová, Šárka Pospíšilová, Vítězslav Bryja   +12 more
doaj   +1 more source

Cyclosporine A therapy of chronic lymphoblastic leukemia‐related pancytopenia: A case report

Clinical Case Reports, 2022
To explore the clinical characteristics, diagnosis, and treatment of chronic lymphocytic leukemia with secondary pancytopenia. Here, a case of pancytopenia secondary to chronic lymphocytic leukemia is reported.
Mengying Wang, Ruoyu Meng, Yan Gao, Junxia Huang, Tianlan Li, Chunxia Mao, Shanshan Liu, Yujie Xu, Han Xu, Xianqi Feng   +9 more
doaj   +1 more source

Familial chronic lymphocytic leukemia [PDF]

Current Opinion in Hematology, 2010
Families with multiple individuals affected with chronic lymphocytic leukemia (CLL) and other related B-cell tumors have been described in the literature and strong familial aggregation has been seen in population studies. However, predisposing germline mutations have not been identified.
Lynn R, Goldin, Susan L, Slager, Neil E, Caporaso   +2 more
openaire   +2 more sources