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Chronic lymphocytic leukemia [PDF]
Chronic lymphocytic leukemia (CLL) is the commonest type of leukemia seen in Western countries. It affects an older group of individuals than most other varieties of leukemia, and men more often than women, in a ratio of 2:1. The incidence of CLL is significantly increased in some families.
R. Wayne Rundles, Joseph O. Moore
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Chronic Lymphocytic Leukemia [PDF]
This Special Issue of Cancers, made up of nine articles (four original papers, four reviews, and a brief report), is dedicated to chronic lymphocytic leukemia (CLL) [...]
Vaisitti T., Arruga F., Ferrajoli A.
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Chronic Lymphocytic Leukemia [PDF]
Abstract This update of early stage B-cell chronic lymphocytic leukemia (B-CLL) embraces current information on the diagnosis, biology, and intervention required to more fully develop algorithms for management of this disease. Emphasis on early stage is based on the rapid advancement in our understanding of the disease parameters and our
Kay, Neil E. +7 more
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Chronic Lymphocytic Leukemia [PDF]
AbstractCLL is a rare indication for HCT/Cellular Therapy since it usually follows an indolent course. Allogeneic HCT is considered as standard of care in eligible high-risk patients who have failed at least two classes of modern pathway inhibitor-based therapy, and in select patients with CLL transformed in to an aggressive B-cell lymphoma (Richter ...
Johannes Schetelig, Peter Dreger
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Chronic Lymphocytic Leukemia [PDF]
AbstractThe diagnosis and management of chronic lymphocytic leukemia (CLL) is reviewed, including the basic aspects of epidemiology, molecular biology, and cytogenetics with clinical relevance. The importance of immunophenotype in the differential diagnosis of other lymphoproliferative disorders related to CLL, staging, prognostic factors, promising ...
Bruce D. Cheson, Nelson Kalil
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Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification
Recombinant protein expression has become an invaluable tool in basic and applied research. The accumulated knowledge in this field allowed the expression of thousands of protein targets in a soluble, pure, and homogeneous state, essential for ...
Claudia Ortega +9 more
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Difficulties of anemia diagnosis in patients with B-cell chronic lymphocytic leukemia
Cytopenia commonly occurs in case of chronic lymphocytic leukemia. It can either precede the diagnosis of chronic lymphocytic leukemia or appear at any time during the disease.
I. S. Piskunova +4 more
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Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. Due to its catalytic activity, LPL is involved in metabolic pathways exploited by various solid and hematologic malignancies to provide an extra energy source to the tumor cell.
Daniel Prieto, Pablo Oppezzo
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Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk
The importance of the tumor microenvironment in chronic lymphocytic leukemia is widely accepted. Nevertheless, the understanding of the complex interplay between the various types of bystander cells and chronic lymphocytic leukemia cells is incomplete ...
Martijn HA van Attekum +2 more
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Flow cytometry immunophenotyping has an essential role in distinguishing chronic lymphocytic leukemia from other B-chronic lymphoproliferative disorders. Recently, CD200 is considered as a relatively consistent marker in chronic lymphocytic leukemia.
Sana Dlawar Jalal
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