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Chronic lymphocytic leukemia [PDF]

open access: bronzeCancer, 1978
Chronic lymphocytic leukemia (CLL) is the commonest type of leukemia seen in Western countries. It affects an older group of individuals than most other varieties of leukemia, and men more often than women, in a ratio of 2:1. The incidence of CLL is significantly increased in some families.
R. Wayne Rundles, Joseph O. Moore
openalex   +4 more sources

Chronic Lymphocytic Leukemia [PDF]

open access: yesCancers, 2020
This Special Issue of Cancers, made up of nine articles (four original papers, four reviews, and a brief report), is dedicated to chronic lymphocytic leukemia (CLL) [...]
Vaisitti T., Arruga F., Ferrajoli A.
openaire   +6 more sources

Chronic Lymphocytic Leukemia [PDF]

open access: yesHematology, 2002
Abstract This update of early stage B-cell chronic lymphocytic leukemia (B-CLL) embraces current information on the diagnosis, biology, and intervention required to more fully develop algorithms for management of this disease. Emphasis on early stage is based on the rapid advancement in our understanding of the disease parameters and our
Kay, Neil E.   +7 more
  +9 more sources

Chronic Lymphocytic Leukemia [PDF]

open access: yesHemaSphere, 2018
AbstractCLL is a rare indication for HCT/Cellular Therapy since it usually follows an indolent course. Allogeneic HCT is considered as standard of care in eligible high-risk patients who have failed at least two classes of modern pathway inhibitor-based therapy, and in select patients with CLL transformed in to an aggressive B-cell lymphoma (Richter ...
Johannes Schetelig, Peter Dreger
  +9 more sources

Chronic Lymphocytic Leukemia [PDF]

open access: yesThe Oncologist, 1999
AbstractThe diagnosis and management of chronic lymphocytic leukemia (CLL) is reviewed, including the basic aspects of epidemiology, molecular biology, and cytogenetics with clinical relevance. The importance of immunophenotype in the differential diagnosis of other lymphoproliferative disorders related to CLL, staging, prognostic factors, promising ...
Bruce D. Cheson, Nelson Kalil
openaire   +3 more sources

Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification

open access: yesFrontiers in Microbiology, 2018
Recombinant protein expression has become an invaluable tool in basic and applied research. The accumulated knowledge in this field allowed the expression of thousands of protein targets in a soluble, pure, and homogeneous state, essential for ...
Claudia Ortega   +9 more
doaj   +1 more source

Difficulties of anemia diagnosis in patients with B-cell chronic lymphocytic leukemia

open access: yesОнкогематология, 2021
Cytopenia commonly occurs in case of chronic lymphocytic leukemia. It can either precede the diagnosis of chronic lymphocytic leukemia or appear at any time during the disease.
I. S. Piskunova   +4 more
doaj   +1 more source

Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia: New Insights into Leukemic Progression

open access: yesMolecules, 2017
Lipoprotein lipase (LPL) is a central enzyme in lipid metabolism. Due to its catalytic activity, LPL is involved in metabolic pathways exploited by various solid and hematologic malignancies to provide an extra energy source to the tumor cell.
Daniel Prieto, Pablo Oppezzo
doaj   +1 more source

Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk

open access: yesHaematologica, 2017
The importance of the tumor microenvironment in chronic lymphocytic leukemia is widely accepted. Nevertheless, the understanding of the complex interplay between the various types of bystander cells and chronic lymphocytic leukemia cells is incomplete ...
Martijn HA van Attekum   +2 more
doaj   +1 more source

The contribution of CD200 to the diagnostic accuracy of Matutes score in the diagnosis of chronic lymphocytic leukemia in limited resources laboratories.

open access: yesPLoS ONE, 2021
Flow cytometry immunophenotyping has an essential role in distinguishing chronic lymphocytic leukemia from other B-chronic lymphoproliferative disorders. Recently, CD200 is considered as a relatively consistent marker in chronic lymphocytic leukemia.
Sana Dlawar Jalal
doaj   +1 more source

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