Results 191 to 200 of about 95,190 (307)

Real-World Treatment Patterns and Outcomes of Zanubrutinib in Chronic Lymphocytic Leukemia and Small Lymphocytic Leukemia (CLL/SLL). [PDF]

open access: yesCancer Med
Krackeler ML   +11 more
europepmc   +1 more source

Malignant lymphoma supervening in chronic lymphocytic leukemia and related disorders. Richter's syndrome: A study of 25 cases [PDF]

open access: bronze, 1981
Jean‐Luc Harousseau   +5 more
openalex   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Unveiling Cell‐Type‐Specific Immune Reactions in Human Blood Following Varied Fruit and Vegetable Blends Interventions

open access: yesMolecular Nutrition &Food Research, EarlyView.
Paired peripheral‐blood RNA‐seq from MiBLEND was deconvolved with CIBERSORTx to profile leukocyte composition and cell‐type‐specific transcriptomic responses to seven fruit‐and‐vegetable blends. Deconvolution yielded 22 leukocyte subtypes that correlated with laboratory WBC reports (R = 0.886, p ≤ 0.01).
Yueqin He   +3 more
wiley   +1 more source

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