Results 231 to 240 of about 281,573 (395)

The Role of Tumor Microenvironment and Targeted Therapy in Chronic Lymphocytic Leukemia. [PDF]

open access: yesCurr Issues Mol Biol
Saleh K   +13 more
europepmc   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, EarlyView.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Fludarabine: a new agent with major activity against chronic lymphocytic leukemia [PDF]

open access: bronze, 1989
MJ Keating   +9 more
openalex   +1 more source

Delving Into the Dialogue between Epigenetic Modifications and Immunometabolism in Cancer

open access: yesAdvanced Genetics, EarlyView.
Epigenetic modifications—including DNA, histone, and RNA modifications—and their interplay play pivotal roles in tumorigenesis and progression. The crosstalk between tumor immunometabolism and epigenetic regulation has garnered significant attention, as metabolites serve as epigenetic modulators to modulate immune cell activation, differentiation, and ...
Xiaowen Xie   +5 more
wiley   +1 more source

Expression of HERV-K and embryonic genes in chronic lymphocytic leukemia and their association with therapy regimens. [PDF]

open access: yesBlood Adv
Matteucci C   +19 more
europepmc   +1 more source

Malignant lymphoma supervening in chronic lymphocytic leukemia and related disorders. Richter's syndrome: A study of 25 cases [PDF]

open access: bronze, 1981
Jean‐Luc Harousseau   +5 more
openalex   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

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