Results 21 to 30 of about 281,573 (395)

Chronic Lymphocytic Leukemia [PDF]

open access: yesThe Oncologist, 1999
AbstractThe diagnosis and management of chronic lymphocytic leukemia (CLL) is reviewed, including the basic aspects of epidemiology, molecular biology, and cytogenetics with clinical relevance. The importance of immunophenotype in the differential diagnosis of other lymphoproliferative disorders related to CLL, staging, prognostic factors, promising ...
Bruce D. Cheson, Nelson Kalil
openaire   +3 more sources

T LYMPHOCYTE SUBSETS STUDIED IN A PATIENT WITH TWO ASSOCIATED HEMATOLOGIC NEOPLASIAS – CHRONIC LYMPHOCYTIC LEUKEMIA B AND CHRONIC MYELOID LEUKEMIA [PDF]

open access: yesRomanian Journal of Medical Practice, 2019
Quantification of various cellular subpopulations facilitates the monitoring of hematological diseases, including chronic lymphocytic leukemia. Variations in the proportions of regulatory T cells in peripheral blood have been described in patients with
Georgiana Ene   +3 more
doaj   +1 more source

Determinants of Time-to-Death of Chronic Lymphocytic Leukemia Patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia

open access: yesCancer Informatics, 2023
Background: Leukemia is a group of cancers that usually begin in the bone marrow and results in a large number of abnormal white blood cells. Chronic Lymphocytic Leukemia is the most prevalent leukemia in Western countries, with an estimated incidence ...
Gedam Derbew Addisia   +9 more
doaj   +1 more source

Case report: Identification of atypical mantle cell lymphoma with CCND3 rearrangement by next-generation sequencing

open access: yesFrontiers in Oncology, 2023
The t(11;14) (q13;q32) translocation resulting in overexpression of cyclin D1 is the major oncogenic mechanism in mantle cell lymphoma (MCL). Most MCLs can be diagnosed based on morphological features, cyclin D1 expression, and IGH/CCND1 rearrangement ...
Luomengjia Dai   +21 more
doaj   +1 more source

Chronic lymphocytic leukemia and the central nervous system: a clinical and pathological study. [PDF]

open access: yes, 1996
Chronic lymphocytic leukemia is the most common human leukemia but infrequently causes neurologic symptoms. We have reviewed all previously reported cases of chronic lymphocytic leukemia in the CNS along with three new cases; one patient was diagnosed ...
Cramer, SC   +3 more
core   +2 more sources

Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

open access: yesNature Network Boston, 2022
Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. We characterized the whole genome,
F. Nadeu   +51 more
semanticscholar   +1 more source

Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution

open access: yesFrontiers in Immunology, 2017
Efficient and accurate high-throughput DNA sequencing of the adaptive immune receptor repertoire (AIRR) is necessary to study immune diversity in healthy subjects and disease-related conditions.
Stefano Vergani   +7 more
doaj   +1 more source

Multi-Compartment and Multi-Host Vector Suite for Recombinant Protein Expression and Purification

open access: yesFrontiers in Microbiology, 2018
Recombinant protein expression has become an invaluable tool in basic and applied research. The accumulated knowledge in this field allowed the expression of thousands of protein targets in a soluble, pure, and homogeneous state, essential for ...
Claudia Ortega   +9 more
doaj   +1 more source

Difficulties of anemia diagnosis in patients with B-cell chronic lymphocytic leukemia

open access: yesОнкогематология, 2021
Cytopenia commonly occurs in case of chronic lymphocytic leukemia. It can either precede the diagnosis of chronic lymphocytic leukemia or appear at any time during the disease.
I. S. Piskunova   +4 more
doaj   +1 more source

A Case of Hyperkalemia Versus Pseudohyperkalemia in Chronic Lymphocytic Leukemia [PDF]

open access: yes, 2020
Introduction: Both hyperkalemia and pseudohyperkalemia occur in the emergency department. True hyperkalemia necessitates emergent treatment while pseudohyperkalemia requires recognition to prevent inappropriate treatment.
Geary, Sean P., Le, Rachel D.
core   +1 more source

Home - About - Disclaimer - Privacy