Results 111 to 120 of about 2,728,064 (259)

Metacognition and headache: which Is the role in childhood and adolescence? [PDF]

open access: yes, 2017
Headache, in particular migraine, is one of the most frequent neurological symptoms in children and adolescents and it affects about 60% of children and adolescents all over the world.
Calderoni, D   +5 more
core   +2 more sources

Galcanezumab in chronic migraine

open access: yesNeurology, 2018
Objective To evaluate the efficacy and safety of galcanezumab, a humanized monoclonal antibody that selectively binds to calcitonin gene-related peptide, in the preventive treatment of chronic migraine.
H. Detke   +5 more
semanticscholar   +1 more source

Increase in trigeminal ganglion neurons that respond to both CGRP and PACAP in mouse models of chronic migraine and post-traumatic headache.

open access: yesPain, 2020
A large body of animal and human studies indicate that blocking peripheral calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide (PACAP) signaling pathways may prevent migraine episodes and reduce headache ...
Zhaohua Guo   +3 more
semanticscholar   +1 more source

Understanding migraine using dynamical network biomarkers [PDF]

open access: yesarXiv, 2014
Background: Mathematical modeling approaches are becoming ever more established in clinical neuroscience. They provide insight that is key to understand complex interactions of network phenomena, in general, and interactions within the migraine generator network, in particular.
arxiv  

Assessment of acute headache in adults - what the general physician needs to know. [PDF]

open access: yes, 2018
Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal   +9 more
core   +1 more source

Effects of add-on ultramicronized n-palmitol ethanol amide in patients suffering of migraine with aura. a pilot study [PDF]

open access: yes, 2018
Background: Palmitoyl ethanol amide (PEA) is an endogenously produced substance showing anti-nociceptive effect through both receptor and non-receptor mediated effects at the level of different cellular and tissue sites.
Caroleo, Mc   +9 more
core   +2 more sources

Bistable dynamics underlying excitability of ion homeostasis in neuron models [PDF]

open access: yes, 2013
When neurons fire action potentials, dissipation of free energy is usually not directly considered, because the change in free energy is often negligible compared to the immense reservoir stored in neural transmembrane ion gradients and the long-term energy requirements are met through chemical energy, i.e., metabolism.
arxiv   +1 more source

Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

open access: yesArquivos de Neuro-Psiquiatria
Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital.
Mariana Tedeschi Benatto   +6 more
doaj   +1 more source

Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease) [PDF]

open access: yes, 2018
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and chronic diseases(hypertension,dyslipidaemia,diabetes mellitus,chronic kidney disease,cardiovascular disease ...
arxiv   +1 more source

Neural plasticity in common forms of chronic headaches [PDF]

open access: yes, 2015
Headaches are universal experiences and among the most common disorders. While headache may be physiological in the acute setting, it can become a pathological and persistent condition.The mechanisms underlying the transition from episodic to chronic ...
Chen, Wei-Ta   +5 more
core   +4 more sources

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