Results 101 to 110 of about 98,841 (309)

Compromised PGF2α signaling in the paraventricular hypothalamic nucleus contributes to the central sensitization of the nitroglycerin-induced chronic migraine in male mice

The Journal of Headache and Pain
Impaired descending inhibitory controls are now understood to exacerbate central sensitization of chronic migraine, yet the underlying neural and molecular mechanisms remain largely elusive.
Xianrong Hu, Lunquan Wu, Li Wang, Congxue Peng, Yunyun Tian, Qian Zhu, Hongwei Zhu, Liang Nie, Li Yin, Yuehui Zhang, Jiang Bian   +10 more
doaj   +1 more source

Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

Arquivos de Neuro-Psiquiatria
Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital.
Mariana Tedeschi Benatto, Lidiane Lima Florencio, Gabriela Ferreira Carvalho, Fabíola Dach, Marcelo Eduardo Bigal, Thaís Cristina Chaves, Débora Bevilaqua-Grossi   +6 more
doaj   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Management of Chronic Migraine in Children and Adolescents: Where are We in 2022?

Pediatric Health, Medicine and Therapeutics, 2022
Robert C Gibler,1 Kaelynn E Knestrick,1 Brooke L Reidy,1,2 Daniel N Lax,3,4 Scott W Powers1,2,4 1Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA; 2Department of Pediatrics ...
Gibler RC, Knestrick KE, Reidy BL, Lax DN, Powers SW   +4 more
doaj  

Migraine generator network and spreading depression dynamics as neuromodulation targets in episodic migraine

, 2013
Migraine is a common disabling headache disorder characterized by recurrent episodes sometimes preceded or accompanied by focal neurological symptoms called aura. The relation between two subtypes, migraine without aura (MWoA) and migraine with aura (MWA)
Dahlem, Markus A.
core   +1 more source

Genes and primary headaches: discovering new potential therapeutic targets [PDF]

, 2013
Genetic studies have clearly shown that primary headaches (migraine, tension-type headache and cluster headache) are multifactorial disorders characterized by a complex interaction between different genes and environmental factors.
De Martino, Paola, Gai, Annalisa, Gentile, Salvatore, Paemeleire, Koen, Pinessi, Lorenzo, Rainero, Innocenzo, Rubino, Elisa, Sarchielli, Paola, Vacca, Alessandro   +8 more
core   +3 more sources

Percutaneous Closure of Patent Foramen Ovale in a Patient With Incomplete Cor Triatriatum Sinister: A Case Report

Journal of Clinical Ultrasound, EarlyView.
We present the case of a 55‐year‐old male who experienced a cryptogenic ischemic stroke, likely due to a patent foramen ovale (PFO) in the setting of an incomplete cor triatriatum sinister (CTS) and a 30 mm GORE Cardioform Septal Occluder was successfully implanted.
Anastasios Apostolos, Maria Drakopoulou, Elias Tolis, Georgios Trantalis, Ioannis Kachrimanidis, Panayotis Vlachakis, Konstantinos Tsioufis, Konstantinos Toutouzas, Konstantina Aggeli   +8 more
wiley   +1 more source

Familial aggregation of migraine and depression: Insights from a large Australian twin sample [PDF]

, 2016
Free to read\ud \ud Objectives: This research examined the familial aggregation of migraine, depression, and their co-occurrence.\ud \ud Methods: Diagnoses of migraine and depression were determined in a sample of 5,319 Australian twins.
Heath, Andrew C, Madden, Pamela A. F, Martin, Nicholas G, Nyholt, Dale R, Yang, Yuanhao, Zhao, Huiying   +5 more
core   +3 more sources

Generative Artificial Intelligence–Driven Clinical Case Simulation in Temporomandibular Disorder Education: ChatGPT Versus Real Patients

Journal of Dental Education, EarlyView.
ABSTRACT Background Temporomandibular disorders (TMDs) and orofacial pain (OFP) demand advanced diagnostic and clinical reasoning skills in dental education. Traditional simulations with real patients face limitations in availability and standardization.
Paula Rodrigues‐Pereira, Maria Amália Pereira Dias‐Calças, Alex Moreira Mélo, Melissa de Oliveira Melchior, Lucas Gaspar Ribeiro, Antônio Pazin‐Filho, Jardel Francisco Mazzi‐Chaves, Laís Valencise Magri   +7 more
wiley   +1 more source

Clinical diagnosis and computer analysis of headache symptoms [PDF]

, 1984
The headache histories obtained from clinical interviews of 600 patients were analysed by computer to see whether patients could be separated systematically into clinical categories and to see whether sets of symptoms commonly reported together differed ...
Drummond, P.D., Lance, J.W.
core   +2 more sources