Results 81 to 90 of about 57,892 (307)

Reducing Exposure Before Birth: An Interrupted Time Series Study of Prenatal Exposure to Fetotoxic Medications Under Risk Management Plans in Canada

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Canada's 2009 risk management plan (RMP) framework has not been evaluated for prenatal exposure impact. Conversely, widely used drugs such as nonsteroidal anti‐inflammatory drugs (NSAIDs) lack RMPs. We assessed first‐trimester exposure to RMP‐regulated medications following regulatory interventions and to NSAIDs following safety publications.
Nahiyan Saiyara Khan   +4 more
wiley   +1 more source

Tackling chronic migraine: current perspectives

open access: yes, 2014
Francisco Javier Carod-Artal Neurology Department, Raigmore Hospital, Inverness, UK; Universitat Internacional de Catalunya, Barcelona, Spain Abstract: In the last decade, several diagnostic criteria and definitions have been proposed for chronic ...
Carod-Artal FJ
core  

Epidemiology of Intensive Nutritional Interventions and Restraints in Hospitalizations for Anorexia Nervosa: Annual National Trends of the United States

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Despite the clinical relevance of enteral and parenteral tube feeding and restraint use in anorexia nervosa (AN), national‐level data on their use have remained limited, particularly for total parenteral nutrition (TPN) and percutaneous endoscopic gastrostomy (PEG).
Hiroyasu Ino   +3 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

open access: yesEpilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni   +5 more
wiley   +1 more source

Compromised PGF2α signaling in the paraventricular hypothalamic nucleus contributes to the central sensitization of the nitroglycerin-induced chronic migraine in male mice

open access: yesThe Journal of Headache and Pain
Impaired descending inhibitory controls are now understood to exacerbate central sensitization of chronic migraine, yet the underlying neural and molecular mechanisms remain largely elusive.
Xianrong Hu   +10 more
doaj   +1 more source

Cutaneous allodynia is more frequent in chronic migraine, and its presence and severity seems to be more associated with the duration of the disease

open access: yesArquivos de Neuro-Psiquiatria
Objective To evaluate cutaneous allodynia among patients with chronic and episodic migraine in a tertiary headache clinic. Methods 80 subjects with episodic migraine and 80 with chronic migraine were assessed in a tertiary hospital.
Mariana Tedeschi Benatto   +6 more
doaj   +1 more source

Motion sickness and migraine: optokinetic stimulation increases scalp tenderness, pain sensitivity in the fingers and photophobia

open access: yes, 2002
The aim of this study was to determine whether scalp tenderness and photophobia, two well-recognized symptoms of migraine, develop during the motion sickness induced by optokinetic stimulation.
Drummond, P.D.
core  

Implications of therapy interruption on monthly migraine days and modified migraine disability assessment in patients treated with erenumab for chronic and episodic migraine: SQUARE study interim results. [PDF]

open access: yes
BACKGROUND There are limited real-world data in Switzerland examining the impact of erenumab, a fully human IgG2 monoclonal antibody targeting the calcitonin gene-related peptide (CGRP) receptor, on migraine-related quality of life.
Meyer, Ina   +29 more
core   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini   +9 more
wiley   +1 more source

Management of Chronic Migraine in Children and Adolescents: Where are We in 2022?

open access: yesPediatric Health, Medicine and Therapeutics, 2022
Robert C Gibler,1 Kaelynn E Knestrick,1 Brooke L Reidy,1,2 Daniel N Lax,3,4 Scott W Powers1,2,4 1Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA; 2Department of Pediatrics ...
Gibler RC   +4 more
doaj  

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