Results 61 to 70 of about 51,838 (261)

1H-MRS reveals abnormal energy metabolism and excitatory-inhibitory imbalance in a chronic migraine-like state induced by nitroglycerin in mice

The Journal of Headache and Pain
Background Chronic migraine is closely related to the dysregulation of neurochemical substances in the brain, with metabolic imbalance being one of the proposed causes of chronic migraine.
Jinggui Gao, Da Wang, Chenlu Zhu, Jian Wang, Tianxiao Wang, Yunhao Xu, Xiao Ren, Kaibo Zhang, Cheng Peng, Jisong Guan, Yonggang Wang   +10 more
doaj   +1 more source

Epidemiology of Intensive Nutritional Interventions and Restraints in Hospitalizations for Anorexia Nervosa: Annual National Trends of the United States

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Despite the clinical relevance of enteral and parenteral tube feeding and restraint use in anorexia nervosa (AN), national‐level data on their use have remained limited, particularly for total parenteral nutrition (TPN) and percutaneous endoscopic gastrostomy (PEG).
Hiroyasu Ino, Nancy S. Jecker, Yoshiyuki Takimoto, Eisuke Nakazawa   +3 more
wiley   +1 more source

Adapting to life with chronic migraine: a qualitative study of lived experiences among multi-ethnic Asian patients

Frontiers in Pain Research
BackgroundChronic migraine is associated with greater disability, productivity losses and reduced quality of life compared to episodic migraine. Limited research has explored the multi-faceted burden of chronic migraine from patients' perspectives and ...
Yasmin Idu Jion, Jun Ying Hor, Jun Zhi Teh, Yi Jing Zhao, Chai Ching Ng, Jiao Jiao Dang, Nijanth Manohararaj, Chew Seah Tan, Sungwon Yoon, Sungwon Yoon   +9 more
doaj   +1 more source

A Multicenter, Open‐Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST)

American Journal of Hematology, EarlyView.
Kenneth I. Ataga, Pablo Bartolucci, Santosh L. Saraf, Vimal K. Derebail, Adlette Inati, Jeffrey D. Lebensburger, Laurie DeBonnett, Rodolfo D. Cancado, Claire C. Sharpe   +8 more
wiley   +1 more source

Facilitating the timely diagnosis of Lennox–Gastaut syndrome: A checklist to support clinical practice

Epileptic Disorders, EarlyView.
Abstract Objective To develop and evaluate a simple‐to‐use checklist to support physicians with the timely diagnosis of Lennox–Gastaut syndrome (LGS). Methods A panel of 10 pediatric and adult epileptologists used the International League Against Epilepsy (ILAE) criteria for LGS classification and definition to develop seven questions for the checklist,
Nicola Specchio, Alexis Arzimanoglou, Stéphane Auvin, Antonio Gil‐Nagel, Lieven Lagae, Rima Nabbout, Susanne Schubert‐Bast, Adam Strzelczyk, Eugen Trinka, J. Helen Cross   +9 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

Epilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni, Karine Brochu, Paolo Federico, Walter Hader, Julia W. Y. Kam, Fady Girgis   +5 more
wiley   +1 more source

From transformation to chronification of migraine: pathophysiological and clinical aspects

The Journal of Headache and Pain, 2020
Chronic migraine is a neurological disorder characterized by 15 or more headache days per month of which at least 8 days show typical migraine features.
M. Torres-Ferrús, F. Ursitti, A. Alpuente-Ruiz, F. Brunello, D. Chiappino, T. de Vries, S. Di Marco, S. Ferlisi, L. Guerritore, N. Gonzalez-Garcia, A. Gonzalez-Martinez, D. Khutorov, M. Kritsilis, A. Kyrou, T. Makeeva, A. Minguez-Olaondo, L. Pilati, A. Serrien, O. Tsurkalenko, D. Van den Abbeele, W. S. van Hoogstraten, C. Lampl, On behalf of School of Advanced Studies of European Headache Federation (EHF-SAS)   +22 more
doaj   +1 more source

Epileptogenic lesions in the Australian epilepsy project: A harmonized 3‐T magnetic resonance imaging protocol and its diagnostic yield

Epilepsia, EarlyView.
Abstract Objective Detection of epilepsy‐causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy‐directed multisite harmonized 3‐T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the ...
David N. Vaughan, David F. Abbott, Amanda Anderson, Greg Fitt, Suyi Ooi, Heath Pardoe, Donna Parker, Yuliya Perchyonok, Eric Pierre, Chris Kokkinos, Robert E. Smith, Michael Stewart, Bahman Tahayori, Chris Tailby, Graeme D. Jackson, the Australian Epilepsy Project Investigators, Zanfina Ademi, Patrick Kwan, Karen Oliver, Mangor Pedersen   +19 more
wiley   +1 more source

Compromised PGF2α signaling in the paraventricular hypothalamic nucleus contributes to the central sensitization of the nitroglycerin-induced chronic migraine in male mice

The Journal of Headache and Pain
Impaired descending inhibitory controls are now understood to exacerbate central sensitization of chronic migraine, yet the underlying neural and molecular mechanisms remain largely elusive.
Xianrong Hu, Lunquan Wu, Li Wang, Congxue Peng, Yunyun Tian, Qian Zhu, Hongwei Zhu, Liang Nie, Li Yin, Yuehui Zhang, Jiang Bian   +10 more
doaj   +1 more source

Components of generalized onset seizures with focal evolution progressing to bilateral tonic–clonic seizures using quantitative electroencephalography in children: Focal or generalized?

Epilepsia, EarlyView.
Abstract Absence seizures evolving to bilateral tonic–clonic seizures may have focal or asymmetric clinical features. Using quantitative electroencephalography (EEG) may evaluate this phenomenon and the involved neuronal network. We conducted a retrospective chart review of pediatric patients with generalized epilepsy and normal brain magnetic ...
Juan Toro‐Perez, Erick Sell, Asif Doja, Ana Suller‐Marti, Katherine Muir, Sarah Healy, Srinivas Bulusu, Sharon Whiting, Roberto Caraballo   +8 more
wiley   +1 more source