Results 41 to 50 of about 55,496 (259)

Patient self rated pain: headache versus migraine a retrospective chart review

Head & Face Medicine
Background The International Classification of Headache Disorders (ICHD-3) uses moderate or severe pain intensity in the diagnostic criterion for migraine.
Elizabeth Toigo, Erin Pellot, Hannah Lyons, Peter McAllister, Martin Taylor   +4 more
doaj   +1 more source

The state of the art in treating patients with a dual diagnosis of chronic migraine and medication-overuse headache

Headache Medicine, 2023
Migraine is a common, highly prevalent genetic neurological disorder. Its most burdensome form is the chronic migraine, which is clinically defined by the presence of headache on ≥15 days/month for longer than three months, with eight or more typical ...
Carla Jevoux, Abouch Krymchantowski, Raimundo Pereira Silva-Néto, Ana Gabriela Krymchantowski, Ervin Michelstaedter Cotrik   +4 more
doaj   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

The botox paradox: beyond episodic and chronic migraine and theneed for a new nomenclature for treatment-induced remission

Headache Medicine
The International Classification of Headache Disorders, 3rd edition (ICHD-3), distinguishes episodic from chronic migraine mainly by headache frequency.
Marcelo Moraes Valença
doaj   +1 more source

Effect of galcanezumab on severity and symptoms of migraine in phase 3 trials in patients with episodic or chronic migraine

The Journal of Headache and Pain, 2021
Background Galcanezumab, a humanized monoclonal antibody that binds calcitonin gene-related peptide, has demonstrated a significant reduction in monthly migraine headache days compared with placebo. Here, we analyze data from 3 randomized clinical trials
Michael Ament, Kathleen Day, Virginia L Stauffer, Vladimir Skljarevski, Mallikarjuna Rettiganti, Eric Pearlman, Sheena K. Aurora   +6 more
doaj   +1 more source

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal

The Journal of Headache and Pain, 2018
Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in peripheral blood samples as a biomarker of chronic migraine.
Mi Ji Lee, Sook-Yeon Lee, Soohyun Cho, Eun-Suk Kang, Chin-Sang Chung   +4 more
doaj   +1 more source

Defining the Differences Between Episodic Migraine and Chronic Migraine [PDF]

Current Pain and Headache Reports, 2011
Chronic migraine (CM) and episodic migraine (EM) are part of the spectrum of migraine disorders, but they are distinct clinical entities. Population-based studies have shown that those with CM demonstrate higher individual and societal burden because they are significantly more disabled than those with EM and have greater impaired quality of life both ...
Katsarava, Zaza, Buse, Dawn C., Manack, Aubrey N., Lipton, Richard B.   +3 more
openaire   +2 more sources

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

OnabotulinumtoxinA in the treatment of patients with chronic migraine: clinical evidence and experience

Therapeutic Advances in Neurological Disorders, 2017
Chronic migraine is a debilitating neurobiological disorder that affects approximately 1.4–2.2% of the population worldwide. Patients with chronic migraine have 15 or more headache days per month, with at least 8 days per month that meet the criteria for
Chia-Chun Chiang, Amaal J. Starling
doaj   +1 more source