Results 51 to 60 of about 57,892 (307)
Treatment of resistant chronic migraine with anti-CGRP monoclonal antibodies: a systematic review
European Journal of Medical Research, 2022 Background Resistant chronic migraine is a highly disabling condition which is very difficult to treat. The majority of the treatments for migraine prophylaxis are nonspecific and present weak safety profiles, leading to low adherence and discontinuation.
Hugo Sevivas, Paula Fresco
doaj +1 more source
Late Response to Anti-CGRP Monoclonal Antibodies in Migraine
, 2023 Objectives: To assess the frequency and characteristics of late responders (>12 weeks) to monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP).
Torelli, Paola +15 more
core +1 more source
Advanced Science, EarlyView.Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo +10 more
wiley +1 more source
Chronic Migraine: Epidemiology, Mechanisms, and Treatment
, 2018 Chronic migraine is a debilitating primary headache disorder associated with high personal, familial, and social impact. The diagnosis is made when there are at least 15 headache days monthly including 8 migraine days per month for at least 3 months. The
Teshamae S. Monteith +1 more
core +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo +3 more
wiley +1 more source
The Journal of Headache and Pain, 2022 Background The pathogenesis of migraine chronification remains unclear. Functional and structural magnetic resonance imaging studies have shown impaired functional and structural alterations in the brains of patients with chronic migraine. The cerebellum
Wei Wang +11 more
doaj +1 more source
Expanding the Phenotype of TUFM‐Related Combined Oxidative Phosphorylation Deficiency 4
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier +2 more
wiley +1 more source
TRPM8 genetic variant is associated with chronic migraine and allodynia
The Journal of Headache and Pain, 2019 Background Many single nucleotide polymorphisms (SNPs) have been reported to be associated with migraine susceptibility. However, evidences for their associations with migraine endophenotypes or subtypes are scarce.
Yu-Hsiang Ling +4 more
doaj +1 more source
Defining the Differences Between Episodic Migraine and Chronic Migraine [PDF]
Current Pain and Headache Reports, 2011 Chronic migraine (CM) and episodic migraine (EM) are part of the spectrum of migraine disorders, but they are distinct clinical entities. Population-based studies have shown that those with CM demonstrate higher individual and societal burden because they are significantly more disabled than those with EM and have greater impaired quality of life both ...
Katsarava, Zaza +3 more
openaire +2 more sources
, 2022 Objective This meta-analysis compared pressure pain sensitivity in trigeminal, cervical spine and remote pain-free areas between migraine patients and headache-free controls considering diagnosis (episodic versus chronic) and sex.
Alburquerque-Sendin, Francisco +11 more
core +1 more source