Results 151 to 160 of about 101,301 (311)

Botulinum neurotoxin and chronic migraine: muscle fiber chemodenervation or nociceptic system modulation?

open access: green, 2015
А. Р. Артеменко   +3 more
openalex   +2 more sources

Psilocybin as a novel treatment for chronic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey   +3 more
wiley   +1 more source

Navigating migraine chronicity: the role of environmental risk factors and triggers [PDF]

open access: gold
Hasan Doğan   +8 more
openalex   +1 more source

Consider melatonin for migraine prevention [PDF]

open access: yes, 2017
An effective migraine prevention alternative with minimal adverse effects Melatonin is an accessible and affordable option for preventing migraine headaches in chronic ...
Langner, Shannon   +2 more
core  

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro   +14 more
wiley   +1 more source

General practice [PDF]

open access: yes, 2004
The remarkable rate of development of medical knowledge and pharmacology affects all medical specialties and in particular general practice, since the latter embraces various aspects of different medical fields. Certain areas of medical practice, such as
Abela, Jurgen C.
core  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Early Detection of Lower Adherence to Long‐Term e‐Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?

open access: yesClinical &Experimental Allergy, EarlyView.
Adherence to e‐Diary reporting was investigated in a blended care setting among pollen allergic patients with heterogeneous cultural backgrounds. A stable ‘higher’ and a more variable ‘lower’ adherence cluster were identified. Early identification of lower adherence is possible and might inform early interventions to improve patient adherence. ABSTRACT
S. Dramburg   +55 more
wiley   +1 more source

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