Results 21 to 30 of about 2,804,111 (259)

Galcanezumab for the prevention of high frequency episodic and chronic migraine in real life in Italy: a multicenter prospective cohort study (the GARLIT study)

The Journal of Headache and Pain, 2021
Background The clinical benefit of galcanezumab, demonstrated in randomized clinical trials (RCTs), remains to be quantified in real life. This study aimed at evaluating the effectiveness, safety and tolerability of galcanezumab in the prevention of high-
F. Vernieri, C. Altamura, N. Brunelli, C. Costa, C. Aurilia, G. Egeo, L. Fofi, V. Favoni, G. Pierangeli, C. Lovati, M. Aguggia, F. D’onofrio, A. Doretti, Paola Di Fiore, C. Finocchi, R. Rao, Frances A. Bono, A. Ranieri, M. Albanese, S. Cevoli, P. Barbanti, Chiara Davide Daniele Stefano Francesca Fabio Ottavia Fra Capogrosso Bertuzzo Spitaleri Messina Trogu Fredia, C. Capogrosso, D. Bertuzzo, D. Spitaleri, S. Messina, Francesca Trogu, F. Frediani, Ottavia Baldi, Francesca Schiano di Cola, L. Manzo, A. Pascarella, G. Alfieri   +32 more
semanticscholar   +1 more source

Long-term safety and tolerability of eptinezumab in patients with chronic migraine: a 2-year, open-label, phase 3 trial

BMC Neurology, 2021
Background Eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody recently approved in the United States for preventive treatment of migraine in adults, was found to be well tolerated in double-blind, placebo-controlled studies in ...
D. Kudrow, R. Cady, B. Allan, S. Pederson, J. Hirman, L. Mehta, B. Schaeffler   +6 more
semanticscholar   +1 more source

Efficacy and safety of fremanezumab for chronic migraine prevention: Multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group trial in Japanese and Korean patients

Headache, 2021
To determine the efficacy and safety of fremanezumab administration in Japanese and Korean patients with chronic migraine (CM).
Fumihiko Sakai, N. Suzuki, Byung-Kun Kim, H. Igarashi, K. Hirata, T. Takeshima, X. Ning, Tomoko Shima, Miki Ishida, Katsuhiro Iba, Hiroyuki Kondo, Nobuyuki Koga   +11 more
semanticscholar   +1 more source

Favorable outcome of early treatment of new onset child and adolescent migraine-implications for disease modification. [PDF]

, 2009
There is evidence that the prevalence of migraine in children and adolescents may be increasing. Current theories of migraine pathophysiology in adults suggest activation of central cortical and brainstem pathways in conjunction with the peripheral ...
A Ferrari, A Fox, A Hershey, A Hershey, AI Scher, AI Scher, Alan M. Rapoport, B Bille, B. L. Peterlin, C Waeber, C Wober, D D’Amico, D Loder, D Marcus, DC Haas, Fred D. Sheftell, G Fuller, HF Boardman, I Abu-Arefeh, JA Charles, JA Charles, James A. Charles, JF Fries, JL Brandes, K Ahoen, KMA Welch, L Pageler, L Peterlin, M Fanicullace, MA Kabbouche, Marielle A. Kabbouche, MC Kruit, ME Bigal, NH Raskin, NT Mathew, NT Mathew, P Winner, R Burstein, R Burstein, R Hering-Hanit, R Lipton, R Monastero, R Petrella, S Solomon, SD Silberstein, SD Silberstein, SL Linder, SL Linder, SL Linder, Steven L. Linder, W Split, WF Stewart, WF Stewart   +52 more
core   +1 more source

Efficacy and safety of eptinezumab in patients with chronic migraine

Neurology, 2020
Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti–calcitonin gene-related peptide monoclonal antibody, in the preventive treatment of chronic migraine (CM). Methods The Prevention of Migraine via Intravenous ALD403 Safety and
R. Lipton, P. Goadsby, Jeffrey T. L. Smith, B. Schaeffler, D. Biondi, J. Hirman, S. Pederson, B. Allan, R. Cady   +8 more
semanticscholar   +1 more source

Barriers to care in episodic and chronic migraine: Results from the Chronic Migraine Epidemiology and Outcomes Study

Headache, 2021
To assess rates of and factors associated with traversing fundamental barriers to good medical outcomes and pharmacologic care in individuals with episodic migraine (EM) and chronic migraine (CM), including socioeconomic status and race.
D. Buse, Cynthia E. Armand, Larry Charleston, M. Reed, K. Fanning, A. Adams, R. Lipton   +6 more
semanticscholar   +1 more source

Characteristic oscillatory brain networks for predicting patients with chronic migraine

The Journal of Headache and Pain, 2023
To determine specific resting-state network patterns underlying alterations in chronic migraine, we employed oscillatory connectivity and machine learning techniques to distinguish patients with chronic migraine from healthy controls and patients with ...
Fu-Jung Hsiao, Wei-Ta Chen, Yu-Te Wu, Li-Ling Hope Pan, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Gianluca Coppola, Shuu-Jiun Wang   +8 more
doaj   +1 more source

Functional connectivity of the visual cortex in chronic migraine before and after medication withdrawal therapy

NeuroImage: Clinical, 2023
Acute withdrawal of headache medication in chronic migraine patients with medication overuse may lead to a dramatic reduction in headache frequency and severity.
Veronica Mäki-Marttunen, Dennis A. Kies, Judith A. Pijpers, Mark A. Louter, Nic J. van der Wee, Serge A.R.B. Rombouts, Sander Nieuwenhuis, Mark Kruit, Gisela M. Terwindt   +8 more
doaj   +1 more source

Cerebral venous hemodynamic abnormalities in episodic and chronic migraine [PDF]

, 2016
Alterations of cerebral venous drainage have been demonstrated in chronic migraine (CM), suggesting that cerebral venous hemodynamic abnormalities (CVHAs) play a role in this condition.
Di Biase, A, DI PIERO, Vittorio, Passarelli, F, PETOLICCHIO, BARBARA, Tatulli, D, TOSCANO, MASSIMILIANO, Vicenzini, E, VIGANO', ALESSANDRO   +7 more
core   +1 more source

New players in the preventive treatment of migraine. [PDF]

, 2015
Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed ...
Mitsikostas, Dimos D, Rapoport, Alan M
core   +3 more sources