Results 21 to 30 of about 2,712,287 (341)
Efficacy and safety of eptinezumab in patients with chronic migraine
Objective To evaluate the efficacy and safety of eptinezumab, a humanized anti–calcitonin gene-related peptide monoclonal antibody, in the preventive treatment of chronic migraine (CM). Methods The Prevention of Migraine via Intravenous ALD403 Safety and
R. Lipton+8 more
semanticscholar +1 more source
To assess rates of and factors associated with traversing fundamental barriers to good medical outcomes and pharmacologic care in individuals with episodic migraine (EM) and chronic migraine (CM), including socioeconomic status and race.
D. Buse+6 more
semanticscholar +1 more source
The purpose of this study was to measure the vestibular function and plasma fibrinogen level in the nitroglycerin (NTG)-induced chronic migraine rats, and explore the effect of defibrinogenation on migraine and associated vestibular dysfunction.
Jilei Zhang+6 more
doaj +1 more source
A prospective real-world analysis of erenumab in refractory chronic migraine
Background Clinical trials have shown the safety and clinical superiority of erenumab compared to placebo in chronic migraine (CM). The aim of this analysis is to evaluate the effectiveness and tolerability of erenumab in a real-world setting in patients
G. Lambru+4 more
semanticscholar +1 more source
Mechanism of Action of OnabotulinumtoxinA in Chronic Migraine: A Narrative Review
To review the literature on the mechanism of action of onabotulinumtoxinA in chronic migraine.
R. Burstein+4 more
semanticscholar +1 more source
Update of Neuromodulation in Chronic Migraine [PDF]
Neuromodulation devices have become an attractive alternative to traditional pharmacotherapy for migraine, especially for patients intolerant to medication or who prefer non-pharmacological options. In the past decades, many studies demonstrated the efficacy of neuromodulation devices in patients with episodic migraine (EM).
Hsiangkuo Yuan, Tzu-Ying Chuang
openaire +3 more sources
Characteristic oscillatory brain networks for predicting patients with chronic migraine
To determine specific resting-state network patterns underlying alterations in chronic migraine, we employed oscillatory connectivity and machine learning techniques to distinguish patients with chronic migraine from healthy controls and patients with ...
Fu-Jung Hsiao+8 more
doaj +1 more source
Refractory Migraine and Chronic Migraine: Pathophysiological Mechanisms [PDF]
Migraine is a complex disorder of the brain whose mechanisms are only now being unravelled. It is common, disabling, and economically costly. Brain imaging has suggested a role for the brainstem. While the disorder is almost certainly inherited, the degree to which this contributes to a treatment refractory state is not clear.
Richard Hargreaves, Peter J. Goadsby
openaire +4 more sources
Background erenumab was safe and effective in clinical trials for the prevention of migraine. However, real-life data are still lacking. Here we report the clinical experience from an Italian real-world setting using erenumab in patients with chronic ...
A. Russo+7 more
semanticscholar +1 more source
Phenotypic features of chronic migraine [PDF]
Chronic migraine is a disabling, under-recognized, and undertreated disorder that increases health burdens. The aim of this study was to evaluate phenotypic features and the relevance of accompanying symptoms of migraine attacks in chronic migraine.This study was conducted as part of an ongoing Turkish Headache Database Study investigating the clinical
Yalın, Osman Özgür+5 more
openaire +5 more sources