Results 91 to 100 of about 2,555,654 (307)
Targeting Cannabinoid 1 Receptor in Macrophages Alleviates Psoriatic Skin Inflammation Through the AUF1–NLRP3 Axis
Advanced Science, EarlyView.Macrophage CB1R emerges as a key driver of psoriatic inflammation by suppressing AUF1‐mediated post‐transcriptional control of NLRP3. CB1R inhibition restores AUF1‐dependent NLRP3 mRNA decay, restrains inflammasome activation, and alleviates psoriasis‐like inflammation.Hongseo Choi, Sukyoung Han, Jinho Kim, Ji Hye Han, Eunsu Kim, Yeonjeong Heo, Minju Lee, Jooyoung Lee, Heerim You, Soyoun Lee, Su‐Hee Han, Ilrok Yoon, Sung Anjeon, Hyerim Kang, Seungyeon Ryu, Hyun‐Ji Park, Eunha Kim, Chul Hwan Bang, Ji Hyun Lee, Josephine M. Egan, Jung‐Woong Kim, Eun Kyung Lee, Wook Kim +22 morewiley +1 more sourceChromosomal Abnormalities, Drug Sensitivity and Resistance in Hematological Malignancies: A Comprehensive Overview by the Francophone Group of Hematological Cytogenetics (GFCH)
American Journal of Hematology, EarlyView.ABSTRACT
Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...Florence Nguyen‐Khac, Audrey Bidet, Elise Chapiro, Nathalie Douet‐Guilbert, Jean‐Baptiste Gaillard, Nada Assaf, Nathalie Auger, Hend Chaker, Jasmine Chauzeix, Inge Govaerts, Hippolyte Guérineau, Christine Lefebvre, Pauline Roynard, Hélène Guermouche, Lucienne Michaux, Marie‐Bérengère Troadec, Lauren Véronèse +16 morewiley +1 more sourceAtypical Chronic Myeloid Leukemia (aCML) [PDF]
, 2009 Review on Atypical Chronic Myeloid Leukemia (aCML), with data on clinics, and the genes ...Hernandez, JM, López, L, Arefi, M, Garcia, JL, Villaescusa, T +4 morecore +1 more sourceDiscontinuation of imatinib in Japanese patients with chronic myeloid leukemia
Haematologica, 2012 It was recently recognized that some chronic myeloid leukemia patients with a complete molecular response could sustain that response after discontinuation of imatinib.Naoto Takahashi, Taiichi Kyo, Yasuhiro Maeda, Takashi Sugihara, Kensuke Usuki, Tatsuya Kawaguchi, Noriko Usui, Shinichiro Okamoto, Yokiko Ohe, Shigeki Ohtake, Kunio Kitamura, Masahide Yamamoto, Hirofumi Teshima, Toshiko Motoji, Toshiharu Tamaki, Kenichi Sawada, Kazuma Ohyashiki +16 moredoaj +1 more sourceNilotinib in the Treatment of Chronic Myeloid Leukemia
Future Oncology, 2018 Nilotinib, a second-generation tyrosine kinase inhibitor, was designed to overcome resistance of a wide range of BCR-ABL mutants to imatinib. When used in the first-line treatment in newly diagnosed chronic myeloid leukemia (CML), it induces faster and deeper molecular responses in higher than imatinib percentage of patients.Sacha, Tomasz, Saglio, Giuseppeopenaire +4 more sourcesA certified plasmid reference material for the standardisation of BCR-ABL1 mRNA quantification by real time quantitative PCR [PDF]
, 2014 Serial quantification of BCR–ABL1 mRNA is an important therapeutic indicator in chronic myeloid leukaemia, but there is a substantial variation in results reported by different laboratories.Mitterbauer, G., Kim, D.-W., S McCarron, Polakova, K.M., Hall, V, Preudhomme, C., K M Polakova, Hall, V., Schimmel, Heinz G., Cross, N.CP., L Foroni, Gerrard, G., Waits, Paula S., Cross, N.C.P., Jansson, Mattias,, Polakova, Km, Ozbek, U (Ugur), E O Leibundgut, El Housni, Hakim, R Ganderton, E Gineikienė, G Martinelli, Kizilors, A., White, H., Corbisier, P., Hayette, S, Colomer, D., Ganderton, R., Mueller, M. C., Kim, D-W, Van der Velden, V. H. J., de Lange, T, P Waits, Wilson, G., Mitterbauer Hohendanner, G, Cross, Nicholas C P., J Nomdedéu, Nagar, M, Nagar, M., Merle, P. A., Clench, T, Müller, M.C., Hochhaus, A., Fletcher, L, Deprez, Ludovic, Milner, B., Jurcek, Tomas, Nymoen, D. A., Andrikovics, H., T Sacha, Touloumenidou, Tasoula, Cayuela, J-M, Boeckx, N., Merle, Pauline A., Lange, T, Emons, H, Wang, L., Wang, L, D-W Kim, T Jurcek, Touloumenidou, T, Trapmann, Stefanie, A Aggerholm, Barbany, G., McCarron, S., V Kairisto, Mazoua, S., Schimmel, H, Polakova, K M, S Hayette, White, H, Barbany, G, H White, C Preudhomme, Cayuela, Jm, G Romeo, R Talmaci, Lin, Feng, K Zoi, Aggerholm, A, Lion, T, Akiki, S., Jurcek, T., Kairisto, V, A Kizilors, Aggerholm, A., Van der Velden, Vh, Mueller, MC, F Lin, Colomer, D, Leibundgut, E O, Hochhaus, A, J Farrugia, Müller, Mc, Milner, B, G Mitterbauer-Hohendanner, Trapmann, S., Leibundgut, Eo, U Ozbek, Waits, P., Daraio, Filomena, Farrugia, J., Nomdedéu, J, Kizilors, Aytug, Preudhomme, C, Wilson, Gillian A., Ozbek, U, Lange, Thoralf, H Andrikovics, Andrikovics, H, El Housni, H, Emons, Hendrik, Deprez, L., Kim, Dong-Wook, Lin, F., Wilkinson, E., S Chudleigh, Dulucq, S., Schimmel, H., Izzo, B., D Colomer, Hayette, S., D Wren, Corbisier, Philippe, P Johnels, Cross, Nc, M Nagar, Zoi, K, V H J Van der Velden, N Boeckx, Bench, Anthony J., Aggerholm, Anni, El Housni, H., Gineikienė, E, H El Housni, Catherwood, M., Kairisto, Veli, Nagar, Meital, Catherwood, Mark Alexander, Hall, Victoria J., Wang, Lihui, Pfeifer, H, R Zadro, Milner, Benedict J., Nymoen, Dag André, Zadro, Renata, Leibundgut, E. O., Kim, Dw, S Trapmann, Fletcher, L., Kairisto, V., Daraio, F, Romeo, Giuliana, K Raudsepp, Akiki, S, Lin, F, L Wang, M Catherwood, Van der Velden, V.H.J., Dulucq, S, Wilson, G, M Jansson, Hochhaus, Andreas, Merle, P A, Nickless, Guillermina, Pajič, T, van der Velden, Vincent, Jansson, M, T Clench, Bench, A, T Touloumenidou, Universitat Autònoma de Barcelona. Departament de Medicina, Müller, M C, Deprez, L, Romeo, G, Foroni, L, Raudsepp, K, Mazoua, Stéphane, Wren, Dörte, Hayette, Sandrine, A Hochhaus, Machová Polakova, Katerina Machová, Foroni, L., Mitterbauer-Hohendanner, G, S Mazoua, Catherwood, M, Ziermann, Janine, F Daraio, S Dulucq, Sacha, T, Chudleigh, Sandra, G Gerrard, Chudleigh, S, G Wilson, Gerrard, Gareth, Farrugia, J, B Milner, M C Müller, P A Merle, Wilkinson, E, L Fletcher, Emons, H., Polakova, K. M., V Hall, Van der Velden, V.HJ., Wren, D., Nickless, G, Pajič, T., Sacha, T., Cross, N C P, Merle, Pa, Pfeifer, Heike, Merle, P.A., Ziermann, J, Touloumenidou, T., Zoi, K., Cross, NCP, Lion, Thomas, Trapmann, S, Wren, D, El Akiki, Susanna, McCarron, S, H Pfeifer, Corbisier, P, Wilkinson, Elizabeth, Pfeifer, H., Jurcek, T, Johnels, P., Boeckx, Nancy, Gerrard, G, N C P Cross, Ziermann, J., Leibundgut, O., Zadro, R., Martinelli, G., Colomer, Dolors, Izzo, B, White, Helen E., Romeo, G., T Pajič, Farrugia, Joanna, H Emons, P Corbisier, A Bench, Lange, T., G Barbany, Foroni, Letizia, Ganderton, Rosalind H., Raudsepp, K., Mitterbauer-Hohendanner, G., J Ziermann, Martinelli, G, Waits, P, Clench, Tim, Ganderton, R, Daraio, F., Zadro, R, H Schimmel, Kim, D-W., Johnels, Petra, Fletcher, Linda, G Nickless, D A Nymoen, Chudleigh, S., Talmaci, R., Mazoua, S, Nymoen, Da, Oppliger Leibundgut, Elisabeth, T Lion, Bench, A., Clench, T., Nickless, G., Gineikienė, E., L Deprez, E Wilkinson, Zoi, Katerina, Boeckx, N, Nymoen, D.A., Leibundgut, E.O., T Lange, Nymoen, D A, J-M Cayuela, Johnels, P, Barbany-Bustinza, Gisela, Sacha, Tomasz, Jansson, M., Mitterbauer-Hohendanner, Gerlinde Juliane, Lion, T., Müller, Martin Christian, Van der Velden, VHJ, Cayuela, J-M., B Izzo, Kizilors, A, Van der Velden, V H J, Van der Velden54, V.H.J., Cayuela, Jean Michel, Ozbek, U., Andrikovics, Hajnalka, Talmaci, R, Nomdedéu, J., Cross, N. C. P., S Akiki, Preudhomme, Claude, Ozbek, Ugur, Pajič, Tadej, Wang, L (Liang), Jansson, Mattias, Deprez, Liesbet, Cayuela, Jean-Michel, Johnels, P. (Petra), Polakova, K.M. (K M), HALL Victoria, DARAIO Filomena, Romeo, G. (Giovanni), Nickless G, Nagar, M. (M), Wilkinson, E. (Emily), Farrugia, J. (Joanna), Fletcher L, Preudhomme, C. (C), MARTINELLI Giovanni, CLENCH Tim, Trapmann S, KIZILORS Aytug, White H, WAITS Paula, MÜLLER Martin, Barbany-Bustinza, G. (Gisela), EL HOUSNI Hakim, LIN Feng, CHUDLEIGH Sandra, VAN DER VELDEN Vincent Hj, Barbany, Gisela, Mitterbauer-Hohendanner G, Corbisier P, Hochhaus A, Schimmel, Heinz, Wilson, Gill, Cayuela, J.-M. (Jean-Michel), RAUDSEPP Kadri, TOULOUMENIDOU Tasoula, Jansson M, SACHA Tomasz, PREUDHOMME Claude, Mazoua, S. (Stéphane), Raudsepp, Kadri, Farrugia J, Deprez L, FLETCHER Linda, PAJIČ Tadej, TALMACI Rodica, Daraio, F. (Filomena), Colomer, D. (Dolors), Barbany G, JURCEK Tomas, Ziermann, J. (J), Akiki S, BENCH Anthony, MILNER Ben, Aggerholm A, Catherwood M, BARBANY Gisela, KIM Dong-Wook, Foroni L, Touloumenidou T, LION Thomas, Nickless, G. (G), Lund University., Müller, M.C. (Marcella), LANGE Thoralf, Leibundgut, Elisabeth Oppliger, Hayette S, Hall, V. (Victoria), Van der Velden VH, EMONS Hendrik, Cross, N.C.P. (N C P), GERRARD Gareth, NOMDEDÉU Josep, Raudsepp K, Romeo G, Schimmel, H. (Heinz), Touloumenidou, T. (T), Cayuela JM, Izzo B, Polakova KM, Dulucq, Stephanie, CATHERWOOD Mark, Bench, Anthony, Milner B, Ganderton, Ros, MERLE Pauline A., Van der Velden, Vincent H. J., Talmaci R, ZOI Katerina, Nomdedeu Guinot, Jose Francisco, Milner, Ben, Waits, P. (P), Mitterbauer-Hohendanner, G. (G), WHITE Helen, Nymoen, Dag A., MITTERBAUER-HOHENDANNER Gerlinde, DULUCQ Stephanie, FARRUGIA Joanna, Andrikovics H, Hochhaus, A. (Andreas), JOHNELS Petra, AKIKI Susanna, BOECKX Nancy, FORONI Letizia, Izzo, Barbara, Emons, H. (Hendrik), Gerrard G, Deprez, L. (Liesbet), Nymoen DA, MCCARRON Sarah, Ozbek, U. (Ugur), Dulucq S, Sacha T, Sacha, T. (T), DEPREZ Liesbet, Müller, Martin C., Hayette, S. (Sandrine), Martinelli, G. (Giovanni), McCarron, S. (S), WREN Dörte, ROMEO Giuliana, Nomdedéu, Josep F., COLOMER D, WANG Lihui, Hall V, Talmaci, Rodica, Catherwood, M. (M.), Lin F, Andrikovics, H. (Hajnalka), Jurcek, T. (Tomáš), Daraio F, MACHOVA POLAKOVA Katerina, Merle PA, NYMOEN Dag A., Lin, F.Y. (Fay), Johnels, Petra,, Pajič, T. (T), Jurcek T, Kim DW, White, Helen H.E., Müller MC, Wilson, G. (G), Akiki, Susanna, CAYUELA Jean-Michel, Kizilors A, Trapmann, S. (S), Martinelli G, Leibundgut EO, Zadro R, Corbisier, P. (Philippe), GINEIKIENĖ Eglė, NICKLESS Guillermina, Gerrard, G. (Gareth), HAYETTE Sandrine, Lange T, Nomdedéu, J. (J), Nagar M, Ganderton R, Wilkinson E, ANDRIKOVICS Hajnalka, Gineikienė, Eglė, WILSON Gill, Kim, D.-W. (D-W), Talmaci, R. (R), OZBEK Ugur, Chudleigh S, Waits, Paula, Bench, A. (Anthony), Preudhomme C, Akiki, S. (Susanna), Lion T, Raudsepp, K. (K), Wren D, Dulucq, S. (Serge), AGGERHOLM Annie, Pfeifer H, Clench T, WILKINSON Elizabeth, Kairisto V, Johnels P, McCarron S, OPPLIGER LEIBUNDGUT Elisabeth, ZADRO Renata, GANDERTON Ros, CROSS Nicholas, Nomdedéu J, Mitterbauer-Hohendanner, Gerlinde, White, Helen, Polakova, Katerina Machova, ZIERMANN Janine, Kizilors, A. (Aytug), CORBISIER Philippe, Martinelli, Giovanni, TRAPMANN Stefanie, Schimmel H, Ozbek U, Cross, Nicholas C. P., Boeckx N, Merle, D. (Delphine), Izzo, B. (Barbara), Mazoua S, JANSSON Mattias, NAGAR Meital, Leibundgut, E.O. (Elisabeth), MAZOUA Stephane, IZZO Barbara, El Housni H, SCHIMMEL Heinz, Gineikienė E, Ziermann J, Pajič T, Hall, Victoria, Wilson G, Gineikiene, E. (Egle), Boeckx, N. (Nancy), Catherwood, Mark, PFEIFER Heike, McCarron, Sarah, Emons H, KAIRISTO Veli, Wang L, Velden, V.H.J. (Vincent) van der, Clench, T. (Tim), Wang, L. (L), Zadro, R. (R), Bench A, Wren, D. (Dörte), Cross NC, Nymoen, D.A. (D A), Waits P, Milner, B. (B), El Housni, H. (Hakim), Zoi K, White, H. (H), HOCHHAUS Andreas +539 morecore +2 more sourcesMolecular Biology of Chronic Myeloid Leukemia [PDF]
International Journal of Hematology, 2001 Detailed information on the crystal structure of the pharmacologically targeted domains of the BCR‐ABL molecule and on its intracellular signaling, which are potentially involved in growth, anti‐apoptosis, metabolism and stemness, has made the study of chronic myeloid leukemia the most successful field in tumor biology.openaire +3 more sourcesFinal Analysis of the BRUIN Phase 1/2 Study Assessing the Safety and Efficacy of Pirtobrutinib Monotherapy in Patients With MCL
American Journal of Hematology, EarlyView.ABSTRACT
Pirtobrutinib, a highly selective, non‐covalent Bruton tyrosine kinase inhibitor (BTKi) previously demonstrated durable efficacy and tolerable safety following covalent (c) BTKi therapy in heavily pretreated relapsed/refractory (R/R) mantle cell lymphoma (MCL).Michael L. Wang, Jonathon B. Cohen, Nirav N. Shah, Wojciech Jurczak, Pier Luigi Zinzani, Chan Y. Cheah, Chaitra S. Ujjani, Youngil Koh, Won Seog Kim, Sunita D. Nasta, Ian Flinn, Benoit Tessoulin, Shuo Ma, Alvaro J. Alencar, David J. Lewis, Jennifer A. Woyach, Kami J. Maddocks, Krish Patel, Yucai Wang, Joanna M. Rhodes, Constantine S. Tam, John F. Seymour, Hirokazu Nagai, Julie M. Vose, Bita Fakhri, Marc S. Hoffmann, Francisco Hernandez‐Ilizaliturri, Andrew D. Zelenetz, Anita Kumar, Talha Munir, Donald E. Tsai, Paolo Abada, Minna Balbas, Jian Li, Denise Wang, Lindsey E. Roeker, Toby A. Eyre +36 morewiley +1 more source
