Results 181 to 190 of about 399,367 (396)

5‐Aza combined with VPA reprograms human T lineage acute leukemia Jurkat cells into B‐cell‐like cells by epigenetic activation of PAX5

Biotechnology Progress, EarlyView.
Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi, Guoxu Zheng, Xu Chen, Baile Zuo, Wei Wang, Yufang Li, Chunmei Zhang, Jie Chu, Xiuli Mu, Weihong Wen, Tao Wang, An‐Gang Yang   +11 more
wiley   +1 more source

Chronic myeloid leukemia associated with impairment of hearing. [PDF]

, 1985
Christopher K. Williams, O. Ogan
openalex   +1 more source

Associations of body mass index and waist circumference with incidence of overall and of 27 site‐specific cancers: a population‐based retrospective cohort study

Cancer Communications, EarlyView.
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim, Bongseong Kim, Kyu‐won Jung, Ga Eun Nam, Wonyoung Jung, Junhee Park, Kyung‐Do Han, Dong Wook Shin   +7 more
wiley   +1 more source

Leukemia and risk of stroke: a Mendelian randomization analysis

BMC Neurology
Background Observational studies suggest an association between leukemia and stroke, but causality remains unclear. Certain leukemia types may increase stroke risk, but variations exist in stroke and mortality rates across leukemia subtypes.
Xiaoyao Yi, Jingrui Zhu, Xiang Zhang, Ning Huang, Yuan Cheng   +4 more
doaj   +1 more source

Blastic phase of Ph1-positive chronic myeloid leukemia and t(3;21) [letter] [PDF]

, 1988
Ana Aventín, Cristina Mecucci, Herman Van den Berghe   +2 more
openalex   +1 more source

Highly Sensitive and Disposable DNA‐Based Electrochemical Biosensor for Detection of Daunorubicin

ChemElectroChem, EarlyView.
Herin, a flower‐like porous MnO2‐modified pencil graphite electrode (MnO2‐PGE) is developed for the electrochemical determination of the anticancer drug daunorubicin and its interaction with dsDNA. The developed electrochemical nanobiosensor has some advantages, such as easy‐to‐handle, cost‐effective, portable, less time‐consuming assay and disposable.
Mukerrem Findik, Keziban Atacan, Emine Guler Akgemci   +2 more
wiley   +1 more source

A comparative study of dibromomannitol and busulfan in the treatment of chronic myeloid leukemia. A study of cancer and leukemia group B [PDF]

, 1987
Richard T. Silver, Rosemarie Mick, Robert Cooper, Rose Ruth Ellison, R Levy, Kurt Brunner, Joel M. Schwartz, James F. Holland   +7 more
openalex   +1 more source

Combined Immediate‐Release and Extended‐Release Formulation of Sodium Valproate Provides Stable Plasma Levels for Inhibition of Histone Deacetylation

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja, Susanna Kääriäinen, Zsófia Lovró, Mia Lundblad, Kristina Drott, Elsa Lilienberg, Marica T. Engström, Karla Saukkonen, Mika Scheinin   +8 more
wiley   +1 more source

Does the breakpoint within the major breakpoint cluster region (M-bcr) influence the duration of the chronic phase in chronic myeloid leukemia? An analytical comparison of current literature [see comments] [PDF]

, 1991
Ken Mills, Peter Benn, GD Birnie
openalex   +3 more sources

Induction of Differentiation of Mouse Myeloid Leukemia M1 Cells by Serum of Patients with Chronic Myeloid Leukemia [PDF]

, 1988
Junko Okabe‐Kado, Yoshio Honma, Moriaki Hayashi, Motoo Hozumi, K Sampi, Masaharu Sakurai, Ken‐ichiro Hino, Nobuyoshi Tsuruoka   +7 more
openalex   +1 more source