Results 171 to 180 of about 2,555,654 (307)

JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado, Koustubh Bavdhankar, Divyani Garg, Francesca Magrinelli, Huw R. Morris, Kailash P. Bhatia   +5 more
wiley   +1 more source

Extraocular Muscle Infiltration in Chronic Myeloid Leukemia

, 2008
Leukemic infiltration of ocular tissue has previously been reported in acute myeloid (AML) and lymphoid leukemia (ALL), and very rarely in chronic lymphoid leukemia (CLL).
Sandeep Randhawa; Eve Moscato; Raghu Mudumbai
core  

Introduction to the Review Series. Chronic myeloid leukemia in 2026. [PDF]

Haematologica
Radich J.
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Onset of chronic myeloid leukemia with complex karyotype in a pregnant patient: case report and revision of literature

, 2017
Nicola Sgherza,1 Elisabetta Abruzzese,2 Gianni Perla,1 Maria Marta Minervini,1 Vincenzo Chiello,1 Natale Sciannamè,3 Nicola Cascavilla1 1Hematology, IRCCS “Casa Sollievo della Sofferenza”, San Giovanni Rotondo (FG), 2Hematology, Sant ...
Cascavilla N, Abruzzese E, Minervini MM, Chiello V, Sciannamè N, Perla G, Sgherza N   +6 more
core  

Generic versus branded imatinib in frontline chronic myeloid leukemia: A systematic review and meta-analysis. [PDF]

Hemasphere
Biswas S, Srivastava Y, Tummala N, Hamadttu A.   +3 more
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Longitudinal Single-Cell RNA Sequencing Reveals Evolution of Microstates and Macrostates in Chronic Myeloid Leukemia. [PDF]

Cancer Res
Frankhouser DE, Zhao D, Fu YH, Dey A, Chen Z, Irizarry J, Rangel Ambriz J, Kanesa Ybarra T, Branciamore S, O'Meally D, Sathianathen RS, Trent JM, Forman SJ, MacLean AL, Kuo YH, Sakamoto KM, Zhang B, Rockne RC, Marcucci G.   +18 more
europepmc   +1 more source

The Transformative Journey of Chronic Myeloid Leukemia [PDF]

International Journal of Hematologic Oncology, 2018
Neelakantan, Pratap, Mead, Adam
openaire   +2 more sources

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source