Results 151 to 160 of about 2,555,654 (307)

Bosutinib: a SRC–ABL tyrosine kinase inhibitor for treatment of chronic myeloid leukemia

Pharmacogenomics and Personalized Medicine, 2013
Fuad El Rassi, Hanna Jean KhouryDivision of Hematology, Department of Hematology and Medical Oncology, the Winship Cancer Institute at Emory University, Atlanta, Georgia, USAAbstract: Bosutinib is one of five tyrosine kinase inhibitors commercially ...
El Rassi F, Khoury HJ
doaj  

Early Chidamide Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation in High‐Risk Myeloid Malignancies: A Prospective Cohort With Time‐Dependent External‐Control Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Chidamide is an oral histone deacetylase inhibitor whose use as early maintenance after allogeneic hematopoietic stem cell transplantation (HSCT) remains insufficiently defined. This prospective single‐center Phase 1/2 cohort included all 47 patients enrolled and treated by March 31, 2026.
Haonan Yang, Qiushi Liang, Zhigang Liu, Xinchuan Chen, Pu Kuang, Tian Dong, Ting Liu, Ting Niu, Yuhuan Zheng, Jie Ji   +9 more
wiley   +1 more source

CSRP1 Drives Helicobacter pylori‐Associated Gastric Cancer Progression via IL‐6/JAK2/STAT3‐Mediated Epithelial–Mesenchymal Transition

iNew Medicine, EarlyView.
Helicobacter pylori infection‐associated chronic gastritis induces CSRP1 upregulation in gastric cancer cells. Elevated CSRP1 activates the IL‐6/JAK2/STAT3 signaling pathway by promoting IL‐6 expression, JAK2 phosphorylation, and STAT3 nuclear translocation.
Chao Li, Wanjing Chen, Yawei He, Yida Lu, Gang Yu, Ruqiong Wei, Raquel Alarcón Rodríguez, Zhengguang Wang   +7 more
wiley   +1 more source

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

Journal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário, T. M. Fucase, P. J. Spencer, J. M. Sciani, J. Clarêncio, G. Rádis‐Baptista, L. L. Casais‐e‐Silva, R. S. El‐Bachá   +7 more
wiley   +1 more source

A Semi‐Automated Microfluidic Platform Employing Machine Learning Analysis to Study Adhesion Kinetics in Acute Myeloid Leukemia

Microscopy Research and Technique, EarlyView.
We have developed a semi‐automated shear flow platform using bright‐field optics and a machine‐learning analysis algorithm to dissect tumor‐microenvironment interactions. The algorithm quantifies the extent of adhesion at the single‐cell level and delivers consistent results within minutes instead of hours, facilitating high‐throughput analysis ...
Driti Ashok, Dennis Raith, Gabriel Kalweit, Maria Kalweit, Anusha Klett, Justus Duyster, Jonas Bermeitinger, Tanja Nicole Hartmann   +7 more
wiley   +1 more source

Development and targeted use of nilotinib in chronic myeloid leukemia

, 2008
Carmen Fava, Hagop Kantarjian, Jorge Cortes, Elias JabbourDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, USAAbstract: The development of imatinib has resulted in sustained hematologic and cytogenetic remissions
Carmen Fava, Hagop Kantarjian, Elias Jabbour, Jorge Cortes   +3 more
core  

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Chronic myeloid leukemia

HemaSphere, 2019
openaire   +3 more sources

Medicaid utilization in children: Condition‐specific incidence and spending

Journal of Hospital Medicine, EarlyView.
Abstract Medicaid insures over half of US children, yet gaps remain in understanding how funds are allocated across the care of nonchronic conditions, the care of chronic conditions, and preventative services. We conducted a retrospective analysis of 7.2 million Medicaid‐enrolled children from 12 states in the 2022 Medicaid Marketscan database. Only 78.
Madelyn Hall, Jay G. Berry, Samir S. Shah, Vineeta Mittal, Matt Hall, Henry T. Puls, Jessica L. Markham   +6 more
wiley   +1 more source

Successful desensitization to bosutinib in chronic myeloid leukemia. [PDF]

Leuk Res Rep
Guedes C, Geraldes R, Regalo S, Alves M, Lopes J, Todo-Bom A, Ribeiro C.   +6 more
europepmc   +1 more source