Results 241 to 250 of about 399,367 (396)

SETD2 loss of function is a recurrent event in advanced-phase chronic myeloid leukemia and contributes to genomic instability: SETD2 loss in Chronic Myeloid Leukemia. [PDF]

open access: yesClin Transl Med
Mancini M   +17 more
europepmc   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre   +5 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said   +10 more
wiley   +1 more source

Machine learning driven dashboard for chronic myeloid leukemia prediction using protein sequences. [PDF]

open access: yesPLoS One
Ahmad W   +5 more
europepmc   +1 more source

Malignancies and immunoglobulin G4‐related disease

open access: yesRheumatology &Autoimmunity, EarlyView.
Immunoglobulin G4‐related disease (IgG4‐RD) is associated with increased cancer risk. Malignancies affect both IgG4‐RD involved organs, such as the lung, pancreas, bile duct, and prostate, and noninvolved organs, such as the gastrointestinal duct. B‐cell neoplasms constitute a proportion of the malignancies linked to this disease.
Jingna Li, Wen Zhang
wiley   +1 more source

Plasmonic Mesoporous Gold‐Based SERS Biosensor for Ovarian Cancer‐Derived Extracellular Vesicles

open access: yesSmall, EarlyView.
The nanoengineered mesoporous gold (mAu)‐based SERS platform enables rapid, sensitive detection of PLAP‐positive extracellular vesicles (EVs) in ovarian cancer (OC), with detection limits as low as 100 EVs mL−1. Achieving over 80% sensitivity and 98% specificity in clinical samples, this cost‐effective, non‐invasive tool shows promise for early cancer ...
Javeria Bashir   +16 more
wiley   +1 more source

Severe Aortic Stenosis and Chronic Myeloid Leukemia: Considerations for Valve Management. [PDF]

open access: yesJACC CardioOncol
Cunningham R   +5 more
europepmc   +1 more source

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