CAR‐T therapy is evolving across four interconnected dimensions: functional engineering, manufacturing innovation, alternative cell sources, and in vivo CAR programming. Together, these advances address limitations in therapeutic efficacy, safety, manufacturing complexity, scalability, and accessibility, providing complementary paths toward the next ...
Yukimi Sakoda
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Editor's Note: Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1-BCR-ABL-JAK2 Complex. [PDF]
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Development of Colonic Polyposis in a Woman With Chronic Myeloid Leukemia Treated With Dasatinib. [PDF]
Pelaez G +8 more
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Clonal and genomic determinants of e1a2 <i>BCR::ABL1</i> chronic myeloid leukemia: A Fi-LMC study. [PDF]
Podvin B +25 more
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A Current Overview of Quality-of-Life Research in Chronic Myeloid Leukemia (CML). [PDF]
Deneberg S.
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Imatinib Resistance in Chronic Myeloid Leukemia Is Associated with Distinct Metabolic, Oxidative, and Autophagic Adaptations in K562-Derived Cell Sublines. [PDF]
Rachid E +5 more
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Effectiveness and Safety of Imatinib and Nilotinib in Chronic Myeloid Leukemia: A Single-Center Study From Southern Morocco. [PDF]
El Mousadik M +9 more
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Chronic Myeloid Leukemia: Historical Perspective, Pathophysiology, and Treatment Advances.
Tungjitviboonkun S, Daran L, Unsuwan S.
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Over the past twenty years, clinical and laboratory studies have led to important new insights into the biology of chronic myeloid leukemia. Basic science has defined the molecular pathogenesis of chronic myeloid leukemia (CML) as unregulated signal transduction by the Bcr-Abl tyrosine kinase.
Charles Sawyers
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