Results 271 to 280 of about 399,367 (396)

Work Ability in Patients with Chronic Myeloid Leukemia: A Danish Nationwide Cohort Study. [PDF]

Cancers (Basel)
Maksten EF, Jensen JF, Thomsen G, Zenas DR, Jørgensen MP, Udby L, Fonager K, Severinsen MT.   +7 more
europepmc   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

Neutrophilic eccrine hidradenitis following dasatinib initiation in a patient with chronic myeloid leukemia. [PDF]

JAAD Case Rep
Watson A, Roberts N, Noble C, Badon H, Cruse A.   +4 more
europepmc   +1 more source

BCR-ABL expression in different subpopulations of functionally characterized Ph+ CD34+ cells from patients with chronic myeloid leukemia [PDF]

, 1996
Véronique Maguer‐Satta, AL Petzer, AC Eaves, CJ Eaves   +3 more
openalex   +1 more source

Twin pregnancy during treatment with asciminib for chronic myeloid leukemia - a case report. [PDF]

Ann Hematol
Gutierrez de Moraes Pereira GBGM, Rocha VA, Barbosa PVR, Cralcev C, de Jesus AV, Spadoni MB, Pereira TVV, Magalhães JPC, Duarte GO, Duffles G, Maia FS, Surita F, Guida JPS, de Souza CA, Costa ML, Pagnano KBB.   +15 more
europepmc   +1 more source

Chronic myeloid leukemia with minor-bcr breakpoint developed hybrid type of blast crisis

, 1998
Tatsuharu Ohno, Shigefusa Hada, Tateo Sugiyama, Takashi Mizumoto, Hiroo Furukawa, Kenichi Nagai   +5 more
openalex   +1 more source

Diagnosis of unexpected acute myeloid leukemia and chronic lymphocytic leukemia: A case report demonstrating the perils of restricted panels in flow cytometric immunophenotyping [PDF]

, 2000
Xiu Yan Xie, Armando Filie, Gregory A. Jasper, Paula Fukushima, Maryalice Stetler‐Stevenson   +4 more
openalex   +1 more source

Imatinib decreases germ cell survival and germline stem cell proliferation in rodent testis ex vivo and in vitro

Andrology, EarlyView.
Abstract Background Imatinib and dasatinib are tyrosine kinase inhibitors (TKIs) increasingly used to treat several diseases in both children and adults at fertile age. We have previously shown that imatinib has adverse effects on developing testis, and imatinib‐treated male patients have been reported to have reduced sperm counts.
Anna Eggert, Sini Laasanen, Mirja Nurmio, Aida Wahlgren, Kirsi Jahnukainen, Kim Eerola, Miisael Nieminen, Opeyemi Olotu, Noora Kotaja, Juho‐Antti Mäkelä, Jorma Toppari   +10 more
wiley   +1 more source

A non‐hormonal reversible contraceptive targeting GSK3α, a protein kinase, essential for epididymal sperm maturation

Andrology, EarlyView.
Abstract Background and objectives Epididymal transit renders key competence to mammalian spermatozoa for fertilizing eggs. Generally, the two paralogs of glycogen synthase kinase 3, GSK3α and GSK3β, functionally overlap except in testis and sperm. We showed that GSK3α is essential for epididymal sperm maturation and fertilization.
Mustfa Kabi, Aditi Khamamkar, Kwaku Kyei‐Baffour, Michel Weïwer, Srinivasan Vijayaraghavan, Souvik Dey   +5 more
wiley   +1 more source

Prevalence of Asymptomatic Premalignant Oesophageal Lesions in Patients With Fanconi Anaemia

Alimentary Pharmacology &Therapeutics, EarlyView.
Clinically relevant endoscopic findings in asymptomatic Fanconi Anemia patients. ABSTRACT Fanconi anaemia (FA), a rare genetic disorder of DNA repair, predisposes to squamous cell carcinomas of head, neck and oesophagus. We assessed the value of screening esophagogastroduodenoscopy (EGD) in 20 asymptomatic adults (median age 23.5, 65% female) with FA ...
Joshua A. Sloan, Nicha Wongjarupong, Vikram Christian, Nabeel Azeem, Kevin O. Turner, C. Prakash Gyawali, Margaret L. MacMillan, John E. Wagner   +7 more
wiley   +1 more source