Results 11 to 20 of about 6,002,276 (336)

Pathogenesis of Chronic Obstructive Pulmonary Disease [PDF]

Clinics in Chest Medicine, 2005
Abstract The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different in susceptible smokers and involves a predominance of CD8+ T lymphocytes,
Macnee, W
openaire   +6 more sources

Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The ISOLDE trial [PDF]

British medical journal, 2000
Objectives To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease.
Spencer, S, Spencer, Sally, Calverley, Peter MA, Jones, Paul W, Jones, PW, Maslen, TK, Burge, P Sherwood, Burge, PS, Calverley, PMA, Maslen, T K, Anderson, JA, Spencer, Sally; id_orcid, Anderson, Julie A   +12 more
core   +2 more sources

Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis

The Lancet Respiratory Medicine, 2022
Summary Background Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity, disability, and mortality worldwide. We aimed to estimate global, regional, and national COPD prevalence and risk factors to guide policy and
D. Adeloye, Peige Song, Yajie Zhu, H. Campbell, Aziz Sheikh, I. Rudan   +5 more
semanticscholar   +1 more source

Global Burden of Chronic Obstructive Pulmonary Disease Through 2050

JAMA Network Open, 2023
Key Points Question What will the global and regional burden of COPD be in terms of cases and prevalence by 2050? Findings In this modeling study, global COPD prevalence was projected to approach 600 million cases worldwide by 2050, which represents a ...
E. Boers, Meredith A Barrett, Jason G. Su, A. Benjafield, Sanjeev Sinha, Leanne Kaye, Heather J. Zar, V. Vuong, Daniela Téllez, R. Gondalia, Mary B. Rice, Carlos M. Nunez, Jadwiga A. Wedzicha, A. Malhotra   +13 more
semanticscholar   +1 more source

Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

The Lancet, 2022
Executive summary Despite substantial progress in reducing the global impact of many non-communicable diseases, including heart disease and cancer, morbidity and mortality due to chronic respiratory disease continues to increase.
D. Stolz, T. Mkorombindo, D. Schumann, A. Agustí, S. Ash, M. Bafadhel, Chunxue Bai, J. Chalmers, G. Criner, S. Dharmage, F. Franssen, Urs Frey, M. Han, N. Hansel, N. Hawkins, R. Kalhan, Melanie Konigshoff, F. Ko, T. Parekh, P. Powell, M. R. Mölken, J. Simpson, D. Sin, Yuanlin Song, B. Suki, T. Troosters, G. Washko, T. Welte, M. Dransfield   +28 more
semanticscholar   +1 more source

Role of clinical questionnaires in optimizing everyday care of chronic obstructive pulmonary disease. [PDF]

, 2011
: Chronic obstructive pulmonary disease (COPD) is a leading cause of disability in all its stages, and death in patients with moderate or severe obstruction.
van der Molen, T, Jones PW, Jones, P., van der Molen, T., Price, D, Price, David, Jones, PW, van der Molen, Thys, Jones, Paul W., Price D, van der Molen T, Price, D.   +11 more
core   +2 more sources

The Impact of Anxiety and Depression in Chronic Obstructive Pulmonary Disease

Advances in Respiratory Medicine, 2023
Highlights Chronic obstructive pulmonary disease (COPD) patients experience a higher level of psychological distress than the general population, including anxiety and/or depression.
M. S. Rahi, B. Thilagar, S. Balaji, Siva Prabhakaran, M. Mudgal, Suganiya Rajoo, P. Yella, Palak Satija, Alsu Zagorulko, K. Gunasekaran   +9 more
semanticscholar   +1 more source

Guidelines of Integrated Traditional Chinese and Western Medicine for Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (2025 Edition) [PDF]

Zhongguo quanke yixue
Chronic obstructive pulmonary disease(COPD) poses a serious threat to human health, making it one of the major global public health burdens. In 2023, an expert consensus group was established to address key clinical questions in the integrated Chinese ...
Guideline Working Group of Integrated Traditional Chinese and Western Medicine Management for Chronic Obstructive Pulmonary Disease
doaj   +1 more source

Prevalence and Risk Factors of COPD in Nepal: A Systematic Review and Meta-Analysis

Journal of Nepal Health Research Council, 2022
Background: Chronic Obstructive Pulmonary Disease is a common, preventable, and treatable disease. Here, we conducted a systematic review of Chronic Obstructive Pulmonary Disease and its risk factors in Nepal for the last two decades.
Pravash Budhathoki, Dhan Bahadur Shrestha, Yub Raj Sedhai, Ramkaji Baniya, Ayush Bhatt, Kabita Chaudhary, Astutee Acharya, Ruja Rajkarnikar, Madan Basnet, Alok Atreya   +9 more
doaj   +1 more source

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta(2)-agonists for chronic obstructive pulmonary disease (Review) [PDF]

, 2011
BackgroundLong-acting bronchodilators comprising long-acting beta(2)-agonists and the anticholinergic agent tiotropiumare commonly used, either on their own or in combination, for managing persistent symptoms of chronic obstructive pulmonary disease ...
Christopher J Cates, Karner, C, Cates, CJ, Charlotta Karner   +3 more
core   +1 more source