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The LancetChronic pancreatitis is a progressive fibroinflammatory disease primarily caused by a complex interplay of environmental and genetic risk factors. It might result in pancreatic exocrine and endocrine insufficiency, chronic pain, reduced quality of life, and increased mortality.
Goosenberg E, Lappin SL.
europepmc +4 more sources
Trimetazidine has Promising Preventive Effects on Experimental Chronic Pancreatitis Rat Model
The Turkish Journal of Gastroenterology, 2022 Background: It was aimed to evaluate the preventive efficacy of trimetazidine in an experimental chronic pancreatitis rat model. Methods: Chronic pancreatitis model was accomplished with caerulein and alcohol administration.
Mustafa Kaplan +6 more
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Case Reports in Gastroenterology, 2023 When the etiology of pancreatitis cannot be determined despite sufficient investigation, recurrence and progression to chronic pancreatitis often involve genetic mutations.
Susumu Horitani +18 more
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Recent advances in the diagnosis and management of chronic pancreatitis [PDF]
The Korean Journal of Internal Medicine, 2019 Chronic pancreatitis is a chronic condition characterized by pancreatic inflammation that causes fibrosis and the destruction of exocrine and endocrine tissues. Chronic pancreatitis is a progressive disease, and no physiological treatment is available to
Chang-Il Kwon +6 more
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Histomorphological Changes in Pancreas and Liver among Chronic Alcoholics- An Autopsy Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: The clinical and pathological association between pancreatitis and alcohol abuse is well recognised, however the concurrence of prevalence of alcoholic related pancreatitis and liver disease is less well studied. Aim: To evaluate frequency
Danish S Shaikh +2 more
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Early diagnosis of chronic pancreatitis
Alʹmanah Kliničeskoj Mediciny, 2023 Chronic pancreatitis is one of the most challenging disorders from the perspective of its early diagnosis and effective treatment. Within the last decade, the diagnosis of early chronic pancreatitis has been firmly introduced into the practice of ...
Igor E. Khatkov +7 more
doaj +1 more source
Is altered central pain processing related to disease stage in chronic pancreatitis patients with pain? An exploratory study. [PDF]
PLoS ONE, 2013 BackgroundThe most dominant feature in chronic pancreatitis is intense abdominal pain. Changes in spinal and/or supraspinal central nervous system pain processing due to visceral nociceptive input play an important role in this pain.
Stefan A W Bouwense +5 more
doaj +1 more source
Longer‐term outcome of acute pancreatitis: 5 years follow‐up
JGH Open, 2021 Background and Aim Following an index episode of acute pancreatitis, sometimes the inflammation subsides completely, but sometimes inflammation persists and progresses to chronic pancreatitis, which may be or may not be preceded by recurrent acute ...
Partha Sarathi Patra, Kshaunish Das
doaj +1 more source
The role of mast cells in the pathogenesis of pain in chronic pancreatitis
BMC Gastroenterology, 2005 Background The biological basis of pain in chronic pancreatitis is poorly understood. Mast cells have been implicated in the pathogenesis of pain in other conditions. We hypothesized that mast cells play a role in the pain of chronic pancreatitis.
Willis William D +5 more
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Clinical pathomorphism of chronic opisthorchosis pancreatitis
Бюллетень сибирской медицины, 2004 192 patients with chronic opisthorchosis pancreatitis (117 women (60,9%) and 75 men (39,1%) being under observation in Tomsk regional hepatologic center from 1970 till 2000) have been included in the protocol of retrospective cohort study.
B. I. Alperovich +2 more
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