R116C mutation of cationic trypsinogen in a Turkish family with recurrent pancreatitis illustrates genetic microheterogeneity of hereditary pancreatitis [PDF]
, 2001 Hereditary pancreatitis is due to heterozygosity for gain-of-function mutations in the cationic trypsinogen gene which result in increased levels of active trypsin within pancreatic acinar cells and autodigestion of the pancreas.
Dertinger, S. +5 more
core +1 more source
Clinical pathomorphism of chronic opisthorchosis pancreatitis
Бюллетень сибирской медицины, 2004 192 patients with chronic opisthorchosis pancreatitis (117 women (60,9%) and 75 men (39,1%) being under observation in Tomsk regional hepatologic center from 1970 till 2000) have been included in the protocol of retrospective cohort study.
B. I. Alperovich +2 more
doaj +1 more source
Post-surgical Pancreatitis Masquerading as Recurrent Neuroendocrine Cancer [PDF]
, 2010 Neuroendocrine tumours of the pancreas can have a spectrum of behaviour from relatively benign to aggressive. Resection can result in cure although metastatic disease is described.
Oniscu, Anca +5 more
core +1 more source
Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss
Cellular Physiology and Biochemistry, 2017 Background/Aims: Chronic pancreatitis is an inflammatory disease of the pancreas characterized by progressive tissue destruction and fibrogenesis. The development of chronic pancreatitis is associated with immune cell dysregulation.
Luguang Chen +6 more
doaj +1 more source
Proteomics portrait of archival lesions of chronic pancreatitis. [PDF]
PLoS ONE, 2011 Chronic pancreatitis is a chronic inflammatory disorder of the pancreas. The etiology is multi-fold, but all lead to progressive scarring and loss of pancreatic function.
Sheng Pan +7 more
doaj +1 more source
Pancreatic islet autotransplantation with total pancreatectomy for chronic pancreatitis [PDF]
, 2013 Achieving pain relief and improving the quality of life are the main targets of treatment for patients with chronic pancreatitis. The use of total pancreatectomy to treat chronic pancreatitis is a radical and in some ways ideal strategy.
Adachi, Tomohiko +5 more
core +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Delayed diagnosis of chronic pancreatitis with cystic fibrosis and pancreas divisium
Medicine Science, 2017 The incidence of pancreatitis in children and adolescents has increased in recent years. The etiology of pancreatitis is more diverse in children compared to adults.
Burcu Volkan +3 more
doaj +1 more source
Health disparities in chronic liver disease
Hepatology, EarlyView., 2022 Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian +3 more
wiley +1 more source
Pathophysiology of acute experimental pancreatitis: Lessons from genetically engineered animal models and new molecular approaches [PDF]
, 2005 The incidence of acute pancreatitis is growing and worldwide population-based studies report a doubling or tripling since the 1970s. 25% of acute pancreatitis are severe and associated with histological changes of necrotizing pancreatitis. There is still
Burkhard Göke +5 more
core +1 more source